1 results match your criteria: "OH (Drs Oria and Peiro); University of Cincinnati Medical College[Affiliation]"
Creation of a novel synthetic amniotic fluid for use in fetal therapy with in vitro testing on human amniotic membranes.
Am J Obstet Gynecol MFM
September 2023
Center for Fetal and Placental Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH (Drs Forde and Oria, Ms Lampe, Mr Martin, and Dr Peiro); Division of Pediatric Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH (Drs Oria and Peiro); University of Cincinnati Medical College, Cincinnati, OH (Drs Forde, Oria, and Peiro).
Background: Normal saline or lactated Ringer's solutions are usually infused at the time of fetal interventions; however, the effect of these fluids on the amniotic membranes has never been assessed. Given both the significant differences between the composition of normal saline solution, lactated Ringer's solution, and amniotic fluid and the significant risk of prematurity after fetal interventions, an investigation is warranted.
Objective: This study aimed to evaluate the effect of current amnioinfusion fluids on the human amnion compared with a novel synthetic amniotic fluid.