17 results match your criteria: "OBEMET Center for Obesity and Metabolic Health[Affiliation]"

Lactate to albumin ratio has limited prognostic value for complications in children under five with burn injuries.

Sci Rep

January 2025

Unidad de Investigación Para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, Av. la Fontana 550, la Molina 15024, Lima, Peru.

Evaluate the prognostic performance of the lactate-to-albumin ratio (LAR) for complications in children 5 years of age or younger with second and/or third degree burn injuries during hospitalization in the intensive care unit of a hospital in Lima, Peru. In this retrospective cohort study, we conducted prognostic tests by analyzing the medical records of children aged ≤ 5 years who suffered second- and/or third-degree burn injuries and were subsequently admitted to the ICU of a Lima-based hospital between 2017 and 2022. The LAR was calculated using lactate and albumin values measured within the first 48 h post-burn.

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Background: The global burden of metabolic diseases is increasing, but estimates of their impact on primary liver cancer are uncertain. We aimed to assess the global burden of primary liver cancer attributable to metabolic risk factors, including high body mass index (BMI) and high fasting plasma glucose (FPG) levels, between 1990 and 2021.

Methods: The total number and age-standardized rates of deaths and disability-adjusted life years (DALYs) from primary liver cancer attributable to each metabolic risk factor were extracted from the Global Burden of Disease Study 1990-2021.

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Examining adverse life experiences, disordered eating behaviors and cognitions and weight loss treatment in Peru.

Eat Behav

November 2024

OBEMET Center for Obesity and Metabolic Health, Lima, Peru; Universidad San Ignacio de Loyola, Lima, Peru; Nutrition and Health Innovation Research Institute, School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia.

Article Synopsis
  • - This study investigates how everyday discrimination, childhood trauma, and verbal abuse related to weight affect disordered eating behaviors in individuals in Peru, focusing on those seeking weight loss treatment versus those not seeking it.
  • - The research included 420 participants who completed measures assessing their disordered eating, experiences of discrimination, and childhood traumas.
  • - The findings reveal that those seeking weight loss treatment exhibited higher levels of disordered eating and that discrimination and childhood abuse are linked to these eating issues, indicating a need to address these psychosocial factors in treatment settings.
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Article Synopsis
  • - Obesity is a major global health concern, with a significant rise in deaths and disability-adjusted life years (DALYs) linked to high body mass index (BMI) from 1990 to 2021, notably increasing by over 2.5 times for both genders.
  • - The main health issues associated with high BMI in 2021 included diabetes, heart disease, and stroke, with low-middle socio-demographic index (SDI) countries experiencing the largest increase in disease burden.
  • - The findings call for urgent monitoring and intervention efforts to address the growing health impact of high BMI from 1990 to 2021, especially given the stable death rates for women and rising rates for men.
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Article Synopsis
  • Exposure to domestic violence can negatively impact mental health and increase substance abuse risks, particularly alcohol abuse among women.
  • The study focused on Peruvian women, analyzing data from over 19,900 participants to examine the link between interparental violence (father’s violence towards mother) and alcohol abuse.
  • Results showed that women who experienced interparental violence had more than double the odds of alcohol abuse, even after adjusting for various confounding factors.
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Association between the presence of and the development of de novo anemia in adults undergoing sleeve gastrectomy.

SAGE Open Med

August 2024

Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, Lima, Peru.

Background: Sleeve gastrectomy has gained prominence in obesity treatment, yet it is not without complications, such as the development of anemia in the medium term. Given the high prevalence of infection in Peru, it is imperative to explore its potential association with this postoperative complication.

Objective: To evaluate the association between the presence of and the development of anemia 12 months after sleeve gastrectomy.

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Global burden of metabolic diseases, 1990-2021.

Metabolism

November 2024

MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China; Key Laboratory of Diagnosis and Treatment for the Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, Zhejiang, China. Electronic address:

Background: Common metabolic diseases, such as type 2 diabetes mellitus (T2DM), hypertension, obesity, hypercholesterolemia, and metabolic dysfunction-associated steatotic liver disease (MASLD), have become a global health burden in the last three decades. The Global Burden of Disease, Injuries, and Risk Factors Study (GBD) data enables the first insights into the trends and burdens of these metabolic diseases from 1990 to 2021, highlighting regional, temporal and differences by sex.

Methods: Global estimates of disability-adjusted life years (DALYs) and deaths from GBD 2021 were analyzed for common metabolic diseases (T2DM, hypertension, obesity, hypercholesterolemia, and MASLD).

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Objective: To evaluate the association between GGT/HDL-C ratio and resolution of MetS in adults after sleeve gastrectomy (SG).

Methods: We conducted a retrospective cohort study using secondary data from a Peruvian bariatric center. The study population consisted of adults aged 18 and above who underwent laparoscopic SG and were diagnosed with MetS prior to the surgery.

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Factors associated with poor adherence to medication in patients with diabetes and hypertension in Peru: findings from a pooled analysis of six years of population-based surveys.

Public Health

June 2024

OBEMET Center for Obesity and Metabolic Health, Lima, Peru; Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Vicerrectorado de Investigación, Universidad San Ignacio de Loyola, Lima, Peru; Nutrition and Health Innovation Research Institute, School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia.

Objective: To evaluate the factors associated with poor medication adherence in patients with DM and HTN in Peru.

Study Design: A cross-sectional study.

Methods: We analyzed data from the Peruvian Demographic and Family Health Survey from 2014 to 2019.

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Hypertension subtypes at high altitude in Peru: Analysis of the Demographic and Family Health Survey 2016-2019.

PLoS One

April 2024

Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, Lima, Peru.

Background: The prevalence of hypertension in Peru has increased over the years. Approximately one third of the Peruvian population lives at high altitudes. This population presents particular physiological, genetic and environmental characteristics that could be related to the prevalence of hypertension and its subtypes.

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Tuberculosis in pregnancy and adverse neonatal outcomes in two peruvian hospitals.

Eur J Obstet Gynecol Reprod Biol X

June 2024

Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, Lima, Peru.

Article Synopsis
  • Tuberculosis (TB) is a major global health concern and can complicate pregnancies by causing symptoms that mimic normal pregnancy changes, potentially leading to serious maternal and neonatal risks.
  • A study in two public hospitals in Lima, Peru focused on pregnant women to assess the impact of pulmonary TB on adverse neonatal outcomes like low birth weight (LBW), prematurity, and small for gestational age (SGA).
  • The results indicated that pregnant women with pulmonary TB face a significantly increased risk (3.52 times higher) of having babies with these adverse outcomes compared to those without TB, highlighting the severity of this health issue.
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Diagnostic performance of the GGT/HDL-C ratio for NAFLD in adults with obesity undergoing bariatric surgery.

Diabetes Res Clin Pract

May 2024

OBEMET Center for Obesity and Metabolic Health, Lima, Peru; Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, Lima, Peru; Nutrition and Health Innovation Research Institute, School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia. Electronic address:

Background: Non-alcoholic fatty liver disease (NAFLD) has become the most frequent liver disease, closely related with metabolic risk factors such as obesity, insulin resistance, dyslipidemia, diabetes mellitus, and metabolic syndrome. In this context, γ-Glutamyl transpeptidase (GGT) and high-density lipoprotein cholesterol (HDL-C) have shown correlations with steatosis severity and metabolic syndrome, respectively. This positions the GGT/HDL-C ratio as a potential diagnostic indicator for NAFLD.

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Background: Intimate partner violence (IPV) in Peru represents a significant public health challenge. IPV can influence women's reproductive and social behaviors, undermining fertility control, and exacerbating unintended pregnancies. Our objective was to assess the association between IPV and pregnancy intention among Peruvian women of reproductive age.

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Determinants of non-institutional childbirth: Evidence from the Peruvian demographic and health survey.

Eur J Obstet Gynecol Reprod Biol X

December 2023

Unidad para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, Lima, Peru.

Objective: We aimed to evaluate the determinants of non-institutional delivery among women of childbearing age in Peru.

Methods: We conducted a secondary analysis of data from the Peru 2019 Demographic and Family Health Survey (ENDES). This multi-stage survey sampling is representative at the urban-rural, regional, and national levels.

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Diagnostic Performance of 2D Shear Wave (2D-SWE) for Liver Fibrosis in Adults Undergoing Bariatric Surgery.

Obes Surg

October 2023

Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, Av. La Fontana 750, 15024, Lima, Peru.

Background: Among the most recent methods to diagnose liver fibrosis is 2D shear wave elastography (2D-SWE). However, the evidence in the Latin population is limited, and there is no consensus on the cutoff points for each stage of fibrosis.

Aim: To evaluate the diagnostic performance of 2D-SWE for liver fibrosis in adults with obesity who underwent bariatric surgery (BS).

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