595 results match your criteria: "Nutrition and Food Security Research Center[Affiliation]"

Association between Mediterranean diet and metabolic health status among adults was not mediated through serum adropin levels.

BMC Public Health

January 2025

Department of Community Nutrition, School of Nutrition and Food Science, Nutrition and Food Security Research Center, Isfahan University of Medical Sciences, PO Box 81745-151, Isfahan, Iran.

Background: Prevalence of metabolic disorders has been increased in recent years around the world. The relationship between Mediterranean diet (MD) with metabolic health status and serum adropin levels has been less examined in Iranian adults. We investigated the association between MD compliance with metabolic health status and adropin hormone in Iranian adults.

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Prediabetes with a considerable progression rate is a primary risk factor for type 2 diabetes, if left untreated. Dietary interventions examining the health effects of prebiotic consumption on health status have been studied in subjects with prediabetes but the results are controversial. This study aimed to investigate whether prebiotic consumption can favorably alter metabolic status as well as anthropometric features in subjects with prediabetes.

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Background: Increased levels of inflammation in cancer patients and survivors can make them more prone to muscle wasting and sarcopenia. Diet can be an appropriate treatment for alleviating patient complications. Therefore, this study was performed to determine the association between sarcopenia and its components with the dietary inflammatory index (DII) among breast cancer survivors.

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Background: Spontaneous abortion (SA) is reported to be associated with Fat Mass And Obesity-Associated FTO genotype and dietary intake of selenium. This research assessed the potential interactions between the risk of SA, dietary selenium intake, and the FTO rs9939609 polymorphism.

Methods: This case-control study encompassed 192 women who experienced SA and 347 control participants.

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The well-established calcineurin inhibitor, tacrolimus, as an immunosuppressive agent, is widely prescribed after organ transplantation. Cytochrome P450 (CYP 450) isoforms are responsible for the metabolism of many features associated with food parameters like phytochemicals, juices, and fruits. This review article summarizes the findings of previous studies to help predict the efficacy or side effects of tacrolimus in the presence of food variables.

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This study investigated the antioxidant and antimicrobial properties, as well as the volatile compounds, of Lactobacillus bulgaricus (L. bulgaricus) postbiotics (at concentration of 150 and 300 mg/L) and their combination with chitosan coatings (0.5% and 1%) on sausage quality (with 100 ppm nitrite) during 40 days of cold storage.

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Article Synopsis
  • Hemodialysis patients often face issues like malnutrition and skin problems, leading researchers to investigate whether zinc supplementation could help improve these conditions.
  • In a double-blind study with 87 participants, those receiving zinc gluconate showed increased appetite and reduced skin itching after 12 weeks, while no major side effects were reported.
  • However, the supplementation did not significantly affect body composition, strength, or other skin abnormalities compared to the placebo group.
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The Associate between Energy-Adjusted Dietary Inflammatory Index and Periodontal Disease: A Cross-Sectional Study.

Int J Prev Med

October 2024

Nutrition and Food Security Research Center and Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Previous studies have shown that the dietary inflammatory index (DII) is associated with different health outcomes. However, few studies have investigated the relationship between DII and oral health. We aimed to assess the association between energy-adjusted dietary inflammatory index (E-DII) and periodontal disease.

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Background: This systematic review and meta-analysis examine the effects of okra consumption on cardiometabolic risk factors in individuals with prediabetes and diabetes. Okra is a widely consumed vegetable with potential health benefits, and understanding its impact on metabolic parameters in these populations is important.

Methods: A comprehensive search of the literature was conducted up to May 2024 in PubMed/Medline, Scopus, and Web of Science to find relevant randomized clinical trials (RCTs) by using following keyword: ("okra" OR "okras" OR "") AND ("intervention" OR "controlled trial" OR "randomized" OR "randomized" OR "randomly" OR "clinical trial" OR "trial" OR "randomized controlled trial" OR "randomized clinical trial" OR "RCT" OR "blinded" OR "placebo" OR "Cross-Over" OR "parallel").

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Introduction: The positive impact of prunes on body measurements and blood pressure has been suggested in previous research.

Purpose: The purpose of this extensive meta-analysis and systematic review was to examine the effects of adult consumption of prunes on anthropometric parameters and blood pressure.

Methods: To identify relevant randomized controlled trials (RCTs) (till August 9th, 2024), databases from ISI Web of Science, Scopus, and PubMed/Medline were searched.

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Purpose: Although total dietary protein intake has been associated with bladder cancer (BC) risk, the effect of the origin (plant or animal) and the substitutions remain to be understood. This study aimed to investigate the effect of total dietary protein, animal-based protein, plant-based protein, and their substitutions with each other on the risk of BC using a pooled analysis of 10 cohort studies.

Methods: The study was conducted within the "BLadder cancer Epidemiology and Nutritional Determinants" (BLEND) study, including 10 prospective cohort studies from several European countries, the United Kingdom, and the United States.

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Investigation of adherence to DASH diet components and reduction of heart failure risk in adults: A case-control study.

ARYA Atheroscler

January 2024

Department of Clinical Nutrition, School of Nutrition and Food Science, Nutrition and Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Heart failure (HF), or congestive Heart failure (CHF), is a heart disorder with a number of symptoms caused by the heart's inability to pump blood. Our aim in conducting this study is to investigate the adherence to dietary approaches to stop hypertension (DASH) diet components and the risk of HF in Iranian adult women and men.

Methods: In this hospital-based, case-control study, we included 340 participants (194 men and 146 women) aged 30-70 years who were recently (less than 6 months) diagnosed with HF.

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Ultra-processed food intake in relation to metabolic health status in Iranian adolescents with overweight and obesity.

Nutr Metab (Lond)

December 2024

Department of Community Nutrition, School of Nutrition and Food Science, Nutrition and Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Many studies have explored the association between food intake and metabolic health. However, research on the association of consuming ultra-processed foods (UPFs) and metabolic health in children and adolescents remains unclear. The objective of our study was to investigate the relation between UPFs consumption and metabolic health status in Iranian adolescents with overweight/obesity.

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Article Synopsis
  • Spontaneous abortion (SA) is a common complication in pregnancy influenced by genetic factors and maternal nutrition.
  • A study analyzed 192 women with a history of SA versus 347 healthy women, examining the impact of dietary carotenoids and specific gene polymorphisms on the occurrence of SA.
  • The findings revealed that higher intake of β-cryptoxanthin might protect against SA only in women with the TT genotype of the related gene, while no significant links were found for other carotenoids.
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Background: One of the most challenging aspects of treating patients facing primary ovarian insufficiency, especially those eligible for controlled ovarian hyperstimulation (COH), is the assessment of ovarian function and response to stimulatory protocols in terms of the number of oocytes retrieved. The lack of consistency between studies regarding the best parameter for response evaluation necessitates a comprehensive statistical analysis of the most commonly utilized ovarian reserve markers (ORM). This systematic review and meta-analysis aims to establish the optimal metric for assessing ovarian reserve among COH candidates.

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Context: Clinical investigation has shown that the addition of saffron or crocin to standard antidiabetic medications improves a patient's metabolic profile, oxidative stress (OS), and inflammatory response. Despite a large number of studies examining the impact of saffron supplementation on OS, inflammation, and renal and liver function parameters, no systematic review or meta-analysis has been conducted to compile the outcomes in patients with type 2 diabetes mellitus (T2DM).

Objective: The current systematic review and meta-analysis was performed to investigate the effect of saffron or crocin intake on OS, inflammation, and renal and liver function parameters in patients with T2DM.

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Gastric ulcer (GU) is the most common health concern that occurs due to an imbalance between gastric protective mucosal and aggressive factors. Ethanol-induced GU in animal models resembles the pathophysiology of human ulcers. Natural products with fewer side effects are highly requested to attenuate their GU effects.

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The association between consumption of dairy products and risk of type 2 diabetes.

Cardiovasc Endocrinol Metab

March 2025

Department of Community Nutrition, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran.

Background: The effects of dairy products on type 2 diabetes mellitus (T2DM) are unclear. Some studies have revealed the beneficial effects, whereas others found harmful effects of dairy products on the risk of T2DM. The objective of the present study was to investigate the association of different types of dairy products with risk of T2DM in Iranian adults.

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Article Synopsis
  • Saffron, derived from Crocus sativus flowers, contains crocin, a compound with potential anti-inflammatory and antioxidant effects, although research results have varied.
  • A meta-analysis of 13 randomized clinical trials found that crocin supplementation significantly lowered levels of inflammatory markers like CRP, TNF-α, and IL-6 while increasing total antioxidant capacity (TAC).
  • The most pronounced effects were observed with doses of 30 mg or more per day over at least 12 weeks, though crocin did not significantly impact erythrocyte sedimentation rate (ESR) or malondialdehyde (MDA) levels.
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Article Synopsis
  • * Herbal medicine, particularly curcumin from turmeric, shows promise as a source of anti-cancer products due to its various health benefits, including antioxidant and anti-inflammatory properties.
  • * Recent research indicates that curcumin can influence noncoding RNAs (like lncRNAs and circRNAs) in cancer, suggesting a mechanism by which it supports tumor suppression and may guide future cancer therapies.
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Purpose: Dietary factors might contribute to the risk of lung cancer by increasing the concentration of inflammatory markers. The literature-derived Dietary Inflammatory Index (DII) has been established to evaluate the inflammatory potential of diet correlated with inflammatory markers. The association between DII scores and the risk of lung cancer has been conflicting.

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The potential protective effects and mechanisms of fasting on neurodegenerative disorders: A narrative review.

Brain Res

November 2024

Center for Global Health Research, Saveetha Medical College & Hospitals, Saveetha Institute of Medical & Technical Sciences, Saveetha University, Chennai, India; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran; Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address:

Article Synopsis
  • - The study reviews the neuroprotective effects of fasting on neurodegenerative disorders and identifies mechanisms like changes in brain structure/function and gut microbiota modulation.
  • - Preclinical research in animal models reveals that fasting influences metabolic pathways, improves cell survival in CNS tumors, and interacts with circadian rhythms and immune responses through gut microbiome changes.
  • - While fasting shows potential as a non-drug treatment for neurodegenerative conditions, more research is needed to support these initial findings and develop effective clinical practices.
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Reply to Kawada: The meta-analysis of nut intake and prostate cancer risk.

Nutr Metab Cardiovasc Dis

October 2024

Nutrition and Food Security Research Center, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address:

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Comparison of food tolerance among bariatric surgery procedures: a systematic review.

Surg Obes Relat Dis

October 2024

Department of General Surgery, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran; Clinical Research Development Unit, Shahid Bahonar Hospital, Kerman University of Medical Sciences, Kerman, Iran. Electronic address:

Article Synopsis
  • - This study aimed to compare the effects of three types of bariatric surgeries—gastric banding (GB), sleeve gastrectomy (SG), and Roux-en-Y gastric bypass (RYGB)—on food tolerance (FT) post-surgery, based on a review of 27 studies involving 4366 adults.
  • - Findings indicated that GB patients had the lowest food tolerance, while SG and RYGB patients showed similar levels of FT, with RYGB patients demonstrating better tolerance for protein-rich foods.
  • - The study assessed food tolerance over a timeframe of 1 to 5 years after surgery, revealing that SG and RYGB patients generally had better food tolerance levels after the first postoperative year, particularly with
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