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Frequency of V1016I and F1534C mutations in the voltage-gated sodium channel gene in Aedes aegypti in Venezuela.

Pest Manag Sci

June 2015

Universidad Autonoma de Nuevo Leon, Facultad de Ciencias Biologicas, San Nicolas de los Garza, Mexico; Universidad de los Andes, Nucleo Universitario Rafael Rangel. Villa Universitaria Pampanito, estado Trujillo, 3102, Venezuela.

Background: The V1016I and F1534C mutations in the voltage-gated sodium channel gene have been associated with resistance to pyrethroids and DDT in Aedes aegypti mosquitoes. A study was carried out to determine the frequency of I1016 and C1534 by real-time PCR in five natural populations of Ae. aegypti in Venezuela during 2008, 2010 and 2012, as well as in a strain selected with 0.

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