A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionh5ngfs6p1pj2alre99h69a3m4qjfovr0): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

Nuclear and Energy Research Institute[A... Publications | LitMetric

222 results match your criteria: "Nuclear and Energy Research Institute[Affiliation]"

A new thioglycolic ester β-cyclodextrin/PdCl in water: An accessible catalyst for the Suzuki-Miyaura coupling reaction.

Carbohydr Polym

February 2023

Organic Department, Chemistry Institute, Federal University of Bahia, Rua Barão do Jeremoabo, Ondina Campus, 40170-115 Salvador, Bahia, Brazil; Interdisciplinary Center for Energy and Environment (CIENAM), Federal University of Bahia, Ondina Campus, 40170-280 Salvador, Bahia, Brazil. Electronic address:

A novel, easily prepared and accessible water-soluble supramolecular catalyst for the Suzuki-Miyaura CC coupling reaction was synthesized and characterized by FTIR, NMR, XRD, SEM, and HR-TEM. An inexpensive Pd(II) source added to the resulting aqueous solution of thioglycolic ester β-cyclodextrin (1-TGA-SH-β-CD/PdCl) showed Pd nanoclusters and efficient catalytic activity for Suzuki-Miyaura CC coupling reactions of aryl halides with aryl boronic acids, employing KCO as base, in an environmentally benign aqueous solution prepared in open flasks. Organic aryl halides including chlorides can produce moderate to excellent yields with aryl boronic acids and a small catalytic amount (0.

View Article and Find Full Text PDF

Periodic mesoporous organosilicas containing naphthalenediimides as organic sensitizers for sulfadiazine photodegradation.

J Hazard Mater

February 2023

Department of Chemical Engineering, University of São Paulo, Av. Prof. Luciano Gualberto, tr. 3, São Paulo 380, SP, Brazil. Electronic address:

In this work, periodic mesoporous organosilicas (PMO) functionalized with the organic sentisizer naphthalenediimide (NDI) were employed as heterogeneous catalysts for the photodegradation of the antibiotic sulfadiazine (SDZ), taken as a model for contaminants of emerging concern (CECs). The catalysts, designated as PMONDI, were prepared by surfactant-directed co-condensation of the precursor N,N'-bis(3-triethoxysilylpropyl)- 1,4,5,8-naphthalenediimide with tetraethoxysilane. The synthesized PMONDI were characterized using transmission electron microscopy, nitrogen adsorption isotherms and small and large angle x-ray scattering.

View Article and Find Full Text PDF

Effects of Notch signaling pathway inhibition by dibenzazepine in acute experimental toxoplasmosis.

Tissue Cell

December 2022

Laboratory of Immunopathology, Institute of Biomedical Sciences, Federal University of Uberlândia, Av. Pará 1720, 38400-902 Uberlândia, Minas Gerais, Brazil. Electronic address:

Notch signaling pathway plays a crucial role in cellular fate across species, being important for the differentiation and development of several cell types. The aim of this study was to evaluate the effect of Notch inhibition pathway by dibenzazepine (DBZ) in histological and inflammatory alterations and, tissue parasitism in acute Toxoplasma gondii infection. For this, C57BL/6 mice were treated with DBZ before infection with T.

View Article and Find Full Text PDF

Stability of fatigued and aged ZTA compared to 3Y-TZP and AlO ceramic systems.

J Mech Behav Biomed Mater

November 2022

Department of Prosthodontics and Periodontology, University of São Paulo, Bauru School of Dentistry, Bauru, SP, Brazil.

To evaluate the effect of fatigue and aging on the crystalline content and reliability of a zirconia-toughened-alumina (ZTA) composite compared to its individual counterpart materials (3Y-TZP and AlO). Thirty-six disc-shaped specimens per group were obtained to comply with ISO 6872:2015. Crystalline content, microstructure and reliability of experimental groups were evaluated in four stages: 1) immediate; 2) aged; 3) fatigued; 4) aged + fatigue.

View Article and Find Full Text PDF

Snakebite envenomation is considered a neglected tropical disease, affecting tens of thousands of people each year. The recommended treatment is the use of antivenom, which is composed of immunoglobulins or immunoglobulin fragments obtained from the plasma of animals hyperimmunized with one (monospecific) or several (polyspecific) venoms. In this review, the efforts made in the improvement of the already available antivenoms and the development of new antivenoms, focusing on snakes of medical importance from sub-Saharan Africa and Latin America, are described.

View Article and Find Full Text PDF

Mucoadhesive Polymers and Their Applications in Drug Delivery Systems for the Treatment of Bladder Cancer.

Gels

September 2022

Nuclear and Energy Research Institute, IPEN-CNEN/SP-University of São Paulo, Av. Prof. Lineu Prestes, No. 2242, Cidade Universitária, São Paulo 05508-000, Brazil.

Bladder cancer (BC) is the tenth most common type of cancer worldwide, affecting up to four times more men than women. Depending on the stage of the tumor, different therapy protocols are applied. Non-muscle-invasive cancer englobes around 70% of the cases and is usually treated using the transurethral resection of bladder tumor (TURBIT) followed by the instillation of chemotherapy or immunotherapy.

View Article and Find Full Text PDF

Melanoma is a highly aggressive skin cancer that requires new approaches for its management. Low-level laser therapy, currently named photobiomodulation therapy (PBM), has been used to improve different conditions but its effects and safe use on melanoma remain unexplored. Herein, we investigated the PBM impact on melanoma cells differing by pigmentation using near-infrared (NIR) and red lasers in vitro.

View Article and Find Full Text PDF

Several diseases or conditions cause dermatological disorders that hinder the process of skin repair. The search for novel technologies has inspired the combination of stem cell (SC) and light-based therapies to ameliorate skin wound repair. Herein, we systematically revised the impact of photobiomodulation therapy (PBM) combined with SCs in animal models of skin wounds and quantitatively evaluated this effect through a meta-analysis.

View Article and Find Full Text PDF

Aplastic anemia (AA) is a rare and serious disorder of hematopoietic stem cells (HSCs) that results in the loss of blood cells due to the failure of the bone marrow (BM). Although BM transplantation is used to treat AA, its use is limited by donor availability. In this sense, mesenchymal stem cells (MSCs) can offer a novel therapeutic approach for AA.

View Article and Find Full Text PDF

The detailed dose analysis at the extremities remains a challenge, without affecting operators' mobility and their tactile sense. Using films loaded with optically stimulated luminescence (OSL) crystals have been studied in order to overcome some of these challenges in 2D dosimetry. In this work, we investigated flexible polymeric films loaded with MgB4O7:Ce,Li to acquire a better understanding of the dependence of the dosimetric signal characteristics on the production process and the influence of using different powder grain sizes.

View Article and Find Full Text PDF

Heavy metals are natural and essential elements of the environment and living beings, produced from natural (e.g. volcanic activity and cosmic ray-induced spallation) and anthropogenic processes (e.

View Article and Find Full Text PDF

Protocol for reducing radiation exposure during pediatric thoracic radiography.

J Med Imaging Radiat Sci

September 2022

Federal University of Health Care Sciences of Porto Alegre, Sarmento Leite Street, 245 - Centro Histórico, Porto Alegre, RS 90050-170, Brazil; Institute of Cardiology, University Foundation of Cardiology of Rio Grande do Sul, Princesa Isabel Avenue, 395 - Santana, Porto Alegre, RS 90040-371, Brazil; São Camilo University, Nazaré Avenue, 1501 - Ipiranga, São Paulo, SP 04263-200, Brazil.

Introduction: This work aims to assess if the anode position during chest radiography of pediatric patients with heart congenital disease (HCD) influences medical image results. The approach is to reverse the orientation of the x-ray tube, with the anode end directed towards the patient's face (anode-heel effect).

Methods: Five specialists analyzed 48 images, 24 from the control group (CG) and 24 with the anode end directed towards the patients' face (experimental group, EC).

View Article and Find Full Text PDF

Background: Tissue hypoxia is a pathological condition characterized by reducing oxygen supply. Hypoxia is a hallmark of tumor environment and is commonly observed in many solid tumors. Non-invasive imaging techniques like positron emission tomography (PET) are at the forefront of detecting and monitoring tissue hypoxia changes in vivo.

View Article and Find Full Text PDF

Use of Sugar Cane Bagasse as Solid Extraction Phase Sorbent to Analyze Hormones from Industrial Effluent.

ACS Omega

March 2022

Center of Chemistry and Environmental (CQMA), Nuclear and Energy Research Institute (IPEN), Avenida Prof. Lineu Prestes 2242, Cidade Universitária, São Paulo, São Paulo 05508-000, Brazil.

Sugar cane bagasse (SCB) is an abundant byproduct of sugar and bioethanol mills. It has been effectively used as a low-cost biosorbent to remove hazardous chemical compounds from a variety of effluent sources. Herein, we report on the preparation of SCB and its use as a solid phase extraction (SPE) sorbent to retain synthetic hormones (ethinylestradiol, drospirenone, and levonorgestrel) from industrial pharmaceutical plant effluent samples prior to LC-MS/MS quantitative analysis.

View Article and Find Full Text PDF

The health care application of ionizing radiation has expanded worldwide during the last several decades. While the health impacts of ionizing radiation improved patient care, inaccurate handling of radiation technology is more prone to potential health risks. Therefore, the present study characterizes the bone dose response using bovine femurs from a slaughterhouse.

View Article and Find Full Text PDF

Organogels (ORGs) are remarkable matrices due to their versatile chemical composition and straightforward preparation. This study proposes the development of ORGs as dual drug-carrier systems, considering the application of synthetic monoketonic curcuminoid (m-CUR) and lidocaine (LDC) to treat topical inflammatory lesions. The monoketone curcuminoid (m-CUR) was synthesized by using an innovative method via a NbCl-acid catalysis.

View Article and Find Full Text PDF

New forms of cancer treatment, which are effective, have simple manufacturing processes, and easily transportable, are of the utmost necessity. In this work, a methodology for the synthesis of radioactive Gold-198 nanoparticles without the use of surfactants was described. The nuclear activated Gold-198 foils were transformed into HAuCl by dissolution using aqua regia, following a set of steps in a specially designed leak-tight setup.

View Article and Find Full Text PDF

In view of the intense interest in applications of silver nanoparticles in products for the medical field and in food preservation packaging due to their antimicrobial properties, the ecotoxicology of silver nanocomposites was evaluated in films. Test with the sea urchin , to evaluate embryonic development and contamination by the action of silver and titanium nanoparticles in polyethylene nanocomposite films presents new results. The silver nanoparticle's stability in polymeric materials can be enhanced by adding carriers, such as titanium dioxide and montmorillonite clay (MMT) without to producing one unfriendly material.

View Article and Find Full Text PDF

The aim of this study was to evaluate surface wear, presence of microcracks and surface irregularities of WaveOne (WO) and WaveOne Gold (WOG) instruments before and after multiple uses. Eight Primary instruments of the WO and WOG systems were evaluated, each one was used to prepare six mesial canals of extracted human mandibular molars. The surface of the instruments was evaluated before use (T0), after instrumentation of three (T1) and six (T2) root canals.

View Article and Find Full Text PDF

Direct conversion of methane to C compounds by oxidative and nonoxidative coupling reactions has been intensively studied in the past four decades; however, because these reactions have intrinsic severe thermodynamic constraints, they have not become viable industrially. Recently, with the increasing availability of inexpensive "green electrons" coming from renewable sources, electrochemical technologies are gaining momentum for reactions that have been challenging for more conventional catalysis. Using solid-state membranes to control the reacting species and separate products in a single step is a crucial advantage.

View Article and Find Full Text PDF

Impact of Resin Composite Viscosity and Fill-technique on Internal Gap in Class I Restorations: An OCT Evaluation.

Oper Dent

September 2021

Regina Maria Puppin-Rontani, DDS, MS, PhD, State University of Campinas (UNICAMP), Piracicaba Dental School, Department of Pediatric Dentistry, Piracicaba, SP, Brazil.

The aim of this in vitro study was to quantitatively evaluate the internal gap of resin composites of high-and low-viscosity used in single- and incremental-fill techniques in Class I cavities exposed to thermal cycling (TC) using optical coherence tomography (OCT). Cavities of 4-mm depth and 3-mm diameter were prepared in 36 third molars randomly distributed into four groups, according to viscosity of restorative resin-based composite (high or low viscosity, all from 3M Oral Care) and technique application (bulk or incremental fill) used (n=9): RC, high-viscosity, incremental-fill, resin-based composite (Filtek Z350 XT Universal Restorative); BF, high-viscosity, bulk-fill, resin-based composite (Filtek One Bulk Fill); LRC, lowviscosity, incremental-fill, resin-based composite (Filtek Z350 XT Flowable Universal Restorative); and LBF, low-viscosity, bulk-fill, resin-based composite (Filtek Flowable Restorative). Single Bond Universal Adhesive system (3M Oral Care) was used in all the experimental groups.

View Article and Find Full Text PDF

Polymeric nanoparticles acting as sources of selenium (Se) are currently an interesting topic in cancer chemotherapy. In this study, polyglycerol dendrimer (DPGLy) was functionalized with seleno-methyl-selenocysteine (SeMeCys) by means of Steglich esterification with 4-dimethylaminopyridine/(l-ethyl-3-(3-dimethylaminopropyl)carbodiimide) (EDC/DMAP) and cerium chloride as cocatalyst in acetonitrile at quantitative yields of 98 ± 1%. The SeMeCys coupling DPGLy efficiency vs.

View Article and Find Full Text PDF

The pore-forming activity of sticholysin I is enhanced by the presence of a phospholipid hydroperoxide in membrane.

Toxicon

December 2021

Centro de Estudio de Proteínas, Facultad de Biología, Universidad de La Habana, CP, 10400, La Habana, Cuba. Electronic address:

Sticholysin I (StI) is a pore-forming toxin (PFT) belonging to the actinoporin protein family characterized by high permeabilizing activity in membranes. StI readily associates with sphingomyelin (SM)-containing membranes originating pores that can lead to cell death. Binding and pore-formation are critically dependent on the physicochemical properties of membrane.

View Article and Find Full Text PDF

A pre-formulation study of tetracaine loaded in optimized nanostructured lipid carriers.

Sci Rep

November 2021

Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Rua Monteiro Lobato 255, Campinas, SP, 13083862, Brazil.

Tetracaine (TTC) is a local anesthetic broadly used for topical and spinal blockade, despite its systemic toxicity. Encapsulation in nanostructured lipid carriers (NLC) may prolong TTC delivery at the site of injection, reducing such toxicity. This work reports the development of NLC loading 4% TTC.

View Article and Find Full Text PDF