External root temperature and its relationship with dentin thickness during gutta-percha removal procedures with ultrasound. An ex vivo study.

Introduction: This study aims to evaluate the temperature rise on the external root surface during gutta-percha removal with two types of ultrasonic tips, and its relationship with the root dentin thickness.

Methods: 56 single-rooted teeth were prepared for gutta-percha removal procedures, conducted for 40 seconds using two types of ultrasonic tips at depths of 6 mm and 11 mm. The temperature generated was measured using a type K thermocouple at three measurement points.

How Argentinian Consumers Perceive the Safety of Irradiated Foods.

Food irradiation is a process used for various purposes, the main function of which is food safety. Although food irradiation has been used to ensure food safety, most consumers are unaware of the basic concepts of irradiation, misinterpreting information and showing a negative perception towards food treated with ionizing radiation. This research aimed to develop the cross-cultural adaptation and validation of the Awareness Scale on Consumption of Irradiated Foods (ASCIF) for the Argentine population and culture.

Element contents in edible seaweeds and assessment of human health from their consumption.

Seaweed, traditionally part of the daily diet of Asian countries, has become a common dish in Western countries. In Brazil, although contributing to lesser amounts, seaweed consumption has been incorporated into the population eating habits. It is well established that seaweed contains (1) several biologically active components and (2) the ability to accumulate minerals and trace elements, both of which are essential and potentially toxic.

Microplastics in Santos São Vicente estuarine - Hotspot in sediments caused by low energy hydrodynamic events in strongly populated areas.

Microplastics (MPs) have emerged as a significant class of contaminants due to their widespread presence in various environmental compartments. The ingestion of these particles poses a risk to both human health and the local biota. The investigation of the Santos estuary reveals the abundance of microplastics in the mangrove sediment.

Comparing solution blow spinning and electrospinning methods to produce collagen and gelatin ultrathin fibers: A review.

Ultrathin fibers have been used to design functional nanostructured materials for technological and biomedical applications. Combining the use of renewable and compatible sources with the emerging alternative SBS (solution blow spinning) technique opens new opportunities for material applications. In this review, we introduce the benefits of SBS over the classical electrospinning technique by following studies that use collagen or gelatin.

Morphodynamics drive the transport and accumulation of anthropogenic microparticles in tropical coastal depositional systems in southeastern Brazil.

A significant limitation in current coastal pollution research is that microplastics (<5 mm) comprise only a fraction of all anthropogenic microparticles (AMP, <5 mm) scale residues. Comprehensive AMP assessments, including those comprising semisynthetic, and modified natural compositions, are lacking. For instance, the accumulation of AMP in different coastal morphological features within a depositional system remains poorly known, fueling long-lasting debates about the distribution process of microparticles.

Heterobivalent Dual-Target Peptide for Integrin-αβ and Neuropeptide Y Receptors on Breast Tumor.

Heterodimer peptides targeting more than one receptor can be advantageous, as tumors can simultaneously express more than one receptor type. For human breast cancer, a promising biological target is tumor angiogenesis through αβ integrin expression. Another promising target is Neuropeptide Y receptors, considering YR is overexpressed in 90% of human breast tumors.

High-performance plasmonics nanostructures in gas sensing: a comprehensive review.

Plasmonic nanostructures have emerged as indispensable components in the construction of high-performance gas sensors, playing a pivotal role across diverse applications, including industrial safety, medical diagnostics, and environmental monitoring. This review paper critically examines seminal research that underscores the remarkable efficacy of plasmonic materials in achieving superior attributes such as heightened sensitivity, selectivity, and rapid response times in gas detection. Offering a synthesis of pivotal studies, this review aims to furnish a comprehensive discourse on the contemporary advancements within the burgeoning domain of plasmonic gas sensing.

Recognizing microplastic deposits on sandy beaches by altimetric positioning, μ-Raman spectroscopy and multivariate statistical models.

Understanding the extent and implications of microplastic (MP) pollution along the São Paulo State coastline in southeastern Brazil is crucial, considering the significant environmental burden imposed by industrial and port activities in this region. This research aims to understand the complex dynamics of MP deposition on sandy beaches, which poses severe environmental risks to coastal ecosystems, marine organisms, and humans. Using a comprehensive five-step methodology-geodetic surveys, sediment collection, μ-RAMAN spectrometry for polymer identification, and multivariate statistical models-we analyzed the distribution of MPs across six coastal compartments (C1 to C6).

Green Nanotechnology Through Papain Nanoparticles: Preclinical in vitro and in vivo Evaluation of Imaging Triple-Negative Breast Tumors.

Background: Recent advancements in nanomedicine and nanotechnology have expanded the scope of multifunctional nanostructures, offering innovative solutions for targeted drug delivery and diagnostic agents in oncology and nuclear medicine. Nanoparticles, particularly those derived from natural sources, hold immense potential in overcoming biological barriers to enhance therapeutic efficacy and diagnostic accuracy. Papain, a natural plant protease derived from , emerges as a promising candidate for green nanotechnology-based applications due to its diverse medicinal properties, including anticancer properties.

A Rare Case of Pulmonary Artery Trunk Aneurysm.

Background: Pulmonary artery trunk aneurysm (PATA) is a rare and complex vascular anomaly characterized by the abnormal dilation of the initial portion of the pulmonary artery, posing significant diagnostic and therapeutic challenges.

Purpose: This clinical case report aims to describe the follow-up of a patient with PATA, emphasizing the role of imaging in diagnosis and monitoring, as well as discussing potential associations with other conditions.

Research Design: The study is designed as a clinical case report, detailing the longitudinal follow-up of a single patient with PATA.

Influence of carbon content and irradiation modes on the antibiotic removal from water using VIS-activated TiO/expanded graphite composite photocatalysts.

TiO/expanded graphite (TiO/EG) composite films were applied to water treatment for sulfadiazine (SDZ) degradation in a continuous flat plate photochemical reactor. The films were synthesized by sol-gel method and deposited on borosilicate glass by airbrush spray coating technique, forming a TiO/C heterojunction. Increasing the amount of carbon promoted more efficient photocatalytic removal of SDZ under simulated sunlight, which increased from 9.

Experimental toothpastes containing β-TCP nanoparticles functionalized with fluoride and tin to prevent Erosive Tooth Wear.

Objectives: The present study aimed to synthesize toothpastes containing Beta- TriCalcium Phosphate (β-TCP) nanoparticles, functionalized with fluoride and tin, and test their ability to reduce erosive tooth wear (ETW).

Methods: Toothpastes were synthesized with the following active ingredients: 1100 ppm of fluoride (as sodium fluoride, F), 3500 ppm of tin (as stannous chloride, Sn), and 800 ppm of β-TCP (Sizes a - 20 nm; and b - 100 nm). Enamel specimens were randomly assigned into the following groups (n = 10): 1.

Primary Motor Area Activity in Phantom Limb Imagery of Traumatic Unilateral Lower Limb Amputees With Phantom Limb Pain.

Introduction: Estimates of the worldwide increase in amputees raises the awareness to solve long-standing problems. Understanding the functional brain modifications after a lower limb amputation (LLA) is one of the first steps towards proposing new rehabilitation approaches. Functional modifications in the central nervous system due the amputation could be involved in prosthesis use failures and Phantom Limb Pain (PLP), increasing costs and overwhelming the health services.

Photodynamic therapy offers a novel approach to managing miltefosine-resistant cutaneous leishmaniasis.

Cutaneous leishmaniasis (CL) is a neglected disease caused by Leishmania parasites. The oral drug miltefosine is effective, but there is a growing problem of drug resistance, which has led to increasing treatment failure rates and relapse of infections. Photodynamic therapy (PDT) combines a light source and a photoactive drug to promote cell death by oxidative stress.

Evaluation of the Inhibitory Potential of Synthetic Peptides Homologous to CDR3 Regions of a Monoclonal Antibody against Bothropic Venom Serine Proteases.

Snakebite accidents, neglected tropical diseases per the WHO, pose a significant public health threat due to their severity and frequency. Envenomation by genus snakes leads to severe manifestations due to proteolytic enzymes. While the antibothropic serum produced by the Butantan Institute saves lives, its efficacy is limited as it fails to neutralize certain serine proteases.

Evaluation of micronuclei, cytomorphometric and cytologic changes of the oral mucosa in hookah and cigarette smokers.

Objective: To analyze the effect of hookah and cigarettes on the oral mucosa of smokers through the use of exfoliative cytology.

Study Design: Smear samples were collected by exfoliative cytology from the tongue of 33 hookah smokers, 22 cigarette smokers, and 30 non-smokers. The selected analyses include micronuclei (MN), metanuclear anomalies, epithelial maturation, and cytomorphology (nuclear area [NA], cytoplasmic area [CA], and NA/CA ratio).

Development of ZTA (80% AlO/20% ZrO) pre-sintered blocks for milling in CAD/CAM systems.

The present work aims to develop a production method of pre-sintered zirconia-toughened-alumina (ZTA) composite blocks for machining in a computer-aided design and computer-aided manufacturing (CAD-CAM) system. The ZTA composite comprised of 80% AlO and 20% ZrO was synthesized, uniaxially and isostatically pressed to generate machinable CAD-CAM blocks. Fourteen green-body blocks were prepared and pre-sintered at 1000 °C.

Cancer mortality in workers at risk of occupational exposure to ionizing radiation in a company in the nuclear sector headquarters in São Paulo.

Objective: To compare cancer mortality among workers exposed to gamma and X radiation and the general population of the city of São Paulo, as well as that of the subgroup monitored with those not monitored for gamma and X radiation in a work unit with ionizing radiation based in the city of São Paulo.

Methods: Between 2016 and 2021, a retrospective open cohort study was carried out with workers who were employed from 08/31/1956 to 12/31/2016 based on data collected at the company and in official institutions. Standardized mortality ratios (SMR) were calculated by sex, age and calendar period of cancers grouped according to type, risk factor and organ system in two analyses: in the external analysis, the mortality of the study population was compared with that of the general population of the city of São Paulo; In the internal analysis, the mortality of the monitored subgroup was compared with that of the subgroup not monitored for gamma and X radiation.

Radioactive Seed Localization for Nonpalpable Breast Lesions: Systematic Review and Meta-Analysis.

Background: This study is a systematic review with meta-analysis comparing radioactive seed localization (RSL) versus radio-guided occult lesion localization (ROLL) and wire-guided localization (WGL) for patients with impalpable breast cancer undergoing breast-conserving surgery and evaluating efficacy, safety, and logistical outcomes. The protocol is registered in PROSPERO with the number CRD42022299726.

Methods: A search was conducted in the Embase, Lilacs, Pubmed, Scielo, Web of Science, and clinicaltrials.

Novel resin-based material containing β-tricalcium phosphate nanoparticles for the reduction of dentin permeability.

Objectives: To synthesize and characterize a novel dentin adhesive containing Beta-Tricalcium Phosphate (β-TCP) nanoparticles and test its ability to reduce dentin permeability (dP).

Methods: Experimental adhesives were prepared by mixing Bis-GMA, TEGDMA, HEMA (50/25/25 wt.%), photo-initiators, and inhibitors.

Sub-10 nm Nanoparticle Detection Using Multi-Technique-Based Micro-Raman Spectroscopy.

Microplastic pollution is a growing public concern as these particles are ubiquitous in various environments and can fragment into smaller nanoplastics. Another environmental concern arises from widely used engineered nanoparticles. Despite the increasing abundance of these nano-sized pollutants and the possibility of interactions with organisms at the sub cellular level, with many risks still being unknown, there are only a few publications on this topic due to the lack of reliable techniques for nanoparticle characterization.