Enhancing nutritional status, growth, and fruit quality of dried figs using organic fertilizers in rain-fed orchards: A case study in Estahban, Iran.

The majority of Iranian fig production is exported, making it one of the world's most well-known healthy crops. Therefore, the main objective of the current experiment was to investigate the effects of various types of organic fertilizers, such as animal manure (cow and sheep), bird manure (partridge, turkey, quail, and chicken), and vermicompost, on the nutritional status of trees, vegetative and reproductive tree characteristics, fruit yield, and fruit quality traits in dried fig cultivar ("Sabz"). According to the findings, applying organic fertilizers, particularly turkey and quail, significantly improves vegetative and reproductive characteristics.

Evaluation of Re- IBA as a novel radiopharmaceutical for bone marrow ablation.

In this study, Ibandronate as a third generation of bisphosphonates was labeled with rhenium-188 radionuclide. Production and quality control of Re-IBA radiopharmaceutical was investigated. The radiation absorbed dose of this radiopharmaceutical was evaluated for adult male based on biodistribution data in mice using the RADAR and Sparks and Aydogan methodologies.

Noninvasive PET imaging of tumor PD-L1 expression with Cu-labeled Durvalumab.

Breast cancer (BrCa) ranks as the most prevalent malignant neoplasm affecting women worldwide. The expression of programmed death-ligand 1 (PD-L1) in BrCa has recently emerged as a biomarker for immunotherapy response, but traditional immunohistochemistry (IHC)-based methods are hindered by spatial and temporal heterogeneity. Noninvasive and quantitative PD-L1 imaging using appropriate radiotracers can serve to determine PD-L1 expression in tumors.

Internal absorbed dose calculation in body organs due to injection of Rhenium-188 labeled to Mu-9 antibody.

The use of radiopharmaceuticals has gained a special place in the diagnosis and treatment of cancers and evaluation of the function of different organs of the body. In this study, the absorbed dose distribution of organs after injection of Re-Mu-9 has been investigated using MIRD method and MCNP-4C simulation code. The Re-Mu-9 labeled was injected the mouse body and the amount of Re-labeled accumulation was evaluated after 1, 4 and 2 4 h.

Enhanced production of withaferin A from the hairy root culture of Withania somnifera via synergistic effect of Methyl jasmonate and β-cyclodextrin.

Due to low amounts of withanolides produced in some plants and high demand for various applications, their biotechnological production is widely researched. The effects of two explant types (i.e.

Development of [64Cu]Cu-NODAGA-RGD-BBN as a Novel Radiotracer for Dual Integrin and GRPR-targeted Tumor PET Imaging.

Background: In this study, [64Cu]Cu-NODAGA-RGD-BBN was prepared and its preclinical assessments were evaluated for PET imaging of GRPR overexpressing tumors.

Methods: NODAGA-RGD-BBN heterodimer peptide was successfully labeled with cyclotronproduced copper-64 at optimized conditions. The radiochemical purity of the radiotracer was checked by HPLC and RTLC methods.

Radiolabeled florescent-magnetic graphene oxide nanosheets: probing the biodistribution of a potential PET-MRI hybrid imaging agent for detection of fibrosarcoma tumor.

Purpose: Radiolabeled graphene oxide (GO) nanosheets has been one of the most extensively studied nanoplatform for in vivo radioisotope delivery. Herein, we describe the functionalization of the surface of GO nanosheets with FeO magnetic nanoparticles, cysteine amino acid as an interface ligand, and cadmium telluride quantum dots.

Materials And Methods: To enable In vivo PET imaging, the GO@FeO-cys-CdTe QDs were labeled with Ga to yield [Ga] Ga-Go@ FeO-Cys-CdTe QDs.

Comparative assessment of direct and indirect cold atmospheric plasma effects, based on helium and argon, on human glioblastoma: an in vitro and in vivo study.

Recent research has highlighted the promising potential of cold atmospheric plasma (CAP) in cancer therapy. However, variations in study outcomes are attributed to differences in CAP devices and plasma parameters, which lead to diverse compositions of plasma products, including electrons, charged particles, reactive species, UV light, and heat. This study aimed to evaluate and compare the optimal exposure time, duration, and direction-dependent cellular effects of two CAPs, based on argon and helium gases, on glioblastoma U-87 MG cancer cells and an animal model of GBM.

Gene Networks Analysis of Reveals New Insights on Key Genes Involved in Response to Low Water Activity.

Background: When , a foodborne bacterium, is exposed to osmotic stress, cellular adaptations increase virulence severity and cellular survival.

Objectives: The aim of the gene network analysis of was to provide insights into the various interactions between the genes involved in cellular survival under low water activity (a).

Materials And Methods: We performed a gene network analysis to identify the gene clusters and hub genes of using Cytoscape in three food samples subjected to a stress after 72 hours.

as fungicide and symbiont: is it safe for human and animals?

species are considered as biological control agents against numerous phytopathogenic fungi. They are also helpful for plants as plant symbiont. This study aimed to identify harmful effects of in laboratory animals.

Defect detection enhancement using Gaussian Sparse Models.

Detecting defects is critical in industrial fabrication, such as pipe welding, where radiography testing (RT) is the gold standard as a non-destructive method for monitoring weld quality and weld corrosion. The extraction of seamless information from radiographic images is critical for this approach. Image processing techniques can improve the quality of radiographic images by enhancing image contrast, especially in flawed regions.

Unleashing the power of colloidal gold immunochromatographic assays for plant virus diagnostics.

The colloidal gold immunochromatographic assay (GICA) has become a popular method for the rapid detection of plant viruses. This assay format uses antibodies labeled with colloidal gold to capture and detect specific viral antigens in plant samples. GICA offers several advantages over traditional laboratory-based methods, including speed, ease of use, cost-effectiveness, and accessibility, making it an attractive option for plant virology diagnostics.

Runaway electrons and their interaction with tungsten wall: a comprehensive study of effects.

Runaway electrons are a notable phenomenon occurring during the operation of a tokamak. Proper material selection for the tokamak's first wall structure and plasma facing components, particularly in large sizes tokamaks like ITER and DEMO, is crucial due to the energy deposition of runaway electrons on plasma facing components during collision events, resulting in severe heat transfer and material damage in the form of melting, corrosion, and fracture. These runaway electrons also contribute to the production of photoneutrons through (γ, n) nuclear reactions, lead to material activation and require remote handling.

Inhibitory effects of cold atmospheric plasma on population growth of the carob moth, Ectomyelois ceratoniae (Lepidoptera: Pyralidae) in laboratory.

Potential sterilizing effects of the atmospheric cold plasma on the carob moth, Ectomyelois ceratoniae Zeller (Lepidoptera: Pyralidae) was studied under laboratory conditions by means of life history experimentation. The results showed that the population growth parameters of the carob moth decreased in all periods of 15 to 60 sec of plasma treatments applied on 1 -day-old eggs. Overall, 19.

Astatine-211 Radiopharmaceuticals; Status, Trends, and the Future.

The low range of alpha particles provides an opportunity to better target cancer cells theoretically leading to the introduction of interesting alpha emitter radiopharmaceuticals including Ac, Pb, etc. The combination of high energy and short range of alpha emitters differentiates targeted radiotherapy from other methods and reduces unwanted cytotoxicity of the cells around the tumoral tissue. Among interesting alpha emitters candidates for targeted therapy, At, one of the radioisotopes with the best optimal decay properties, shows great promise for targeted radiotherapy in some animal prostate cancer xenograft studies and bone micro tumors with significant effects compared to other beta and alpha emitters and also demonstrates interesting properties for clinical applications.

Molecular and biological investigating of tea plant necrotic ring blotch virus as a worldwide threat.

Tea plant necrotic ring blotch virus (TPNRBV) has emerged as a significant threat to tea plantations, primarily in China. Since 2020, similar symptoms have been observed in tea plants in northern Iran, raising concerns about the spread of this viral infection. In this study, we conducted an extensive investigation involving approximately 70 samples collected from both symptomatic and asymptomatic tea plants.

Environmental and geographical conditions influence color, physical properties, and physiochemical composition of pomegranate fruits.

The highest quality pomegranate necessitates a tropical or subtropical environment for proper growth and development. This study evaluated two pomegranate cultivars including Rabab Poost Ghermez Neyriz (RPGN) and Makhmal Malas Shahreza (MMS) for physical traits, biochemical properties, and juice quality in their native locations as well as other warm and arid regions during two growing seasons (2019-2020 and 2020-2021) in Iran. The results showed that cultivars with the maximum redness (a*) were more likely to originate in cooler climates, and the cultivar's responses to changing climates were also different.

Exploring the potential of cold plasma therapy in treating bacterial infections in veterinary medicine: opportunities and challenges.

Cold plasma therapy is a novel approach that has shown significant promise in treating bacterial infections in veterinary medicine. Cold plasma possesses the potential to eliminate various bacteria, including those that are resistant to antibiotics, which renders it a desirable substitute for traditional antibiotics. Furthermore, it can enhance the immune system and facilitate the process of wound healing.

Preparing metallic bulk samples for transmission electron microscopy analysis via laser ablation in an acidic liquid.

The laser ablation process has been presented as a state-of-the-art and robust method for eliminating surface layers of metallic bulk materials on the micro/nanoscale with considerable accuracy and speed. These capabilities make it an ideal instrument for the primary step of metallic bulk sample preparation for transmission electron microscopy (TEM) analysis with minimal damage to the crystal structure of the sample. This work prepared a pure aluminum plate by fiber laser scanning immersed in a 5 % perchloric acid and 95 % ethanol (by volume) solution.

Use of X-Irradiations in Reducing the Waste of Aflatoxin-Contaminated Pistachios and Evaluation of the Physicochemical Properties of the Irradiated Product.

This study investigates the effects of electron beam irradiation (0, 1, 2, 4, and 6 kGy) on , aflatoxin B1 (AFB1), and the physicochemical properties of pistachios. The findings suggested that e-beam significantly reduced the spore population of and the concentration of AFB1 at doses of 4 and 6 kGy. Three AFB1 degradation products were detected via LC-MS analysis and their structures were presented.

Synthesis and Radiolabeling of Glu-Urea-Lys with Tc-Tricarbonyl-Imidazole-Bathophenanthroline Disulfonate Chelation System and Biological Evaluation as Prostate-Specific Membrane Antigen Inhibitor.

The Glu-Urea-Lys (EUK) pharmacophore as prostate-specific membrane antigen (PSMA)-targeted ligand was synthesized, radiolabeled with Tc-tricarbonyl-imidazole-BPS chelation system, and biological activities were evaluated. The strategy [2 + 1] ligand is applied for tricarbonyl labeling. (5-imidazole-1-yl)pentanoic acid as a monodentate ligand and bathophenanthroline disulfonate (BPS) as a bidentate ligand formed a chelate system with Tc-tricarbonyl.

Genetic diversity in Sickleweed (Falcaria vulgaris) and using stepwise regression to identify marker associated with traits.

One of the well-known medicinal plants in the Falcaria genus is Sickleweed. Falcaria species exhibit a high degree of genetic variability, posing challenges in the examination of genetic diversity due to the significant potential for hybridization and introgression among them. Utilizing morphological traits and molecular markers may prove to be a valuable approach in evaluating and harnessing germplasm, considering the current obstacles faced in breeding this medicinal herb.

A systems biology approach to pathogenesis of gastric cancer: gene network modeling and pathway analysis.

Background: Gastric cancer (GC) ranks among the most common malignancies worldwide. This study aimed to find critical genes/pathways in GC pathogenesis.

Methods: Gene interactions were analyzed, and the protein-protein interaction network was drawn.