Biochip-Based Identification of Mycobacterial Species in Russia.

Infections caused by nontuberculous mycobacteria (NTM) are rising globally throughout the world. The number of species isolated from clinical samples is steadily growing, which demands the implementation of a robust diagnostic method with wide specificity. This study was carried out in in 2022-2024 in three clinical antituberculosis centers in the biggest cities of Russia: Moscow, Saint Petersburg, and Novosibirsk.

Modeling of Mycobacterium tuberculosis dormancy in bacterial cultures.

The currently available methods are unable to directly detect dormant forms of Mycobacterium tuberculosis (Mtb) in vivo. The persistence of Mtb in the host body is detectable only in an indirect manner via the immunological response to Mtb-specific antigens. It is commonly recognized that the pathogen prevalently exists in the human body in a latent stage.

[Patients with newly diagnosed benign prostatic hyperplasia].

Unlabelled: The study aimed to characterize patients with newly diagnosed benign prostatic hyperplasia (BPH) and identify patterns that lead to late diagnosis of the disease.

Study Design: Simple open retrospective non-comparative study.

Material And Methods: To determine the frequency of requests for medical care for BPH, the study analyzed medical records of 3544 patients who sought outpatient urological care at the municipal polyclinic # 26 in Novosibirsk in 2013.

Endobronchial valve treatment of destructive multidrug-resistant tuberculosis.

Background: In accordance with the existing hypothesis, the application of an endobronchial valve (EbV) leads to selective curative atelectasis of the affected part of the lung, contributing to early closure of cavities.

Objective: To assess the effect of EbV treatment on the course of tuberculosis (TB).

Methods: We compared the efficacy of EbV treatment and complex second-line treatment in treating patients with destructive pulmonary multidrug-resistant TB (MDR-TB).

Spectrum of urogenital tuberculosis.

Urogenital tuberculosis (UGTB) plays an important role because its complications may be fatal, it significantly reduces quality of life, and it is often associated with AIDS. Diagnosis of UGTB is often delayed. We analyzed 131 case histories of UGTB patients from the years 2009-2011.