Treated wastewater reuse for irrigation: A feasibility study in Portugal.

In an increasing water scarcity and climate-vulnerable global context, treated wastewater represents a vital alternative water source, thereby enhancing resource sustainability. Despite its potential, only roughly 2.5 % of the treated wastewater is reused in the European Union, with Portugal's reuse rate being only 1.

Additively Manufactured Zirconia for Dental Applications with Color Gradation Control.

The current process for creating zirconia reconstructions for teeth is time-consuming, expensive, and results in tool wear and raw material waste. An alternative method, near-net shape additive manufacturing capable of producing samples with color gradient is presented as an innovative and more efficient solution. A low-cost robocasting system, which enabled the co-extrusion of two different ceramic inks, was designed and developed.

Nondestructive Testing of 3D Printed Fiber-Reinforced Polymeric Composites: An Experimental Critical Comparison.

Polymer matrix composite (PMC) materials produced by additive manufacturing are a promising solution with several applications in industry. The presence of defects due to fabrication could undermine the performance of the component structure. PMC performance has been extensively studied using destructive tests, but reliable nondestructive testing (NDT) techniques are essential.

Impact of Fe/Polyphenol Ratio in Iron-gall Ink on Superoxide Formation: Rationalizing Historic Recipes from a Kinetic Study.

Iron-gall inks, a vital part of our written cultural heritage, are at risk of complete loss due to degradation, a potential loss that we must urgently address. These inks are based on Fe-complexes with phenolic compounds, which grow to form a complex network of iron oxyhydroxides. Over time, these black inks turn into brownish tones, with extensive degradation in paper support leading to extensive breaking.

Material Performance Evaluation for Customized Orthoses: Compression, Flexural, and Tensile Tests Combined with Finite Element Analysis.

Orthoses are commonly used for treating injuries to improve the quality of life of patients, with customized orthoses offering significant benefits. Additive manufacturing, especially fused deposition modelling, enhances these benefits by providing faster, more precise, and more comfortable orthoses. The present study evaluates nine polymeric materials printed in horizontal and vertical directions by assessing their performance through compressive, flexural, and tensile tests.

Generic FPGA Pre-Processing Image Library for Industrial Vision Systems.

Currently, there is a demand for an increase in the diversity and quality of new products reaching the consumer market. This fact imposes new challenges for different industrial sectors, including processes that integrate machine vision. Hardware acceleration and improvements in processing efficiency are becoming crucial for vision-based algorithms to follow the complexity growth of future industrial systems.

Adsorption of Carbon Dioxide and Nitrogen in Co(ndc)(dabco) Metal-Organic Framework.

Metal-organic frameworks (MOFs) are promising materials for processes such as carbon dioxide (CO) capture or its storage. In this work, the adsorption of CO and nitrogen (N) in Co(ndc)(dabco) MOF (ndc: 2,6-naphthalenedicarboxylate; dabco: 1,4-diazabicyclo[2.2.

Numerical Fatigue Crack Growth on Compact Tension Specimens under Mode I and Mixed-Mode (I+II) Loading.

This study focused on standard Compact Tension (CT) specimens and two loading modes during the numerical analyses carried out, namely: pure mode I and mixed-mode loading (Modes I+II). Numerical stress intensity factors, K, were calculated using Abaqus 2022 and compared with those given analytically under pure mode I loading, showing very good agreement. Additionally, K, K, and K results obtained from Abaqus were presented for mixed-mode loading, analyzing crack growth and variation through the thickness of the CT specimen.

Ionic Liquid Crystals as Chromogenic Materials.

Ionic liquid crystals (ILCs), a class of soft matter materials whose properties can be tuned by the wise pairing of the cation and anion, have recently emerged as promising candidates for different applications, combining the characteristics of ionic liquids and liquid crystals. Among those potential uses, this review aims to cover chromogenic ILCs. In this context, examples of photo-, electro- and thermochromism based on ILCs are provided.

Functionally Graded Materials and Structures: Unified Approach by Optimal Design, Metal Additive Manufacturing, and Image-Based Characterization.

Functionally Graded Materials (FGMs) can outperform their homogeneous counterparts. Advances in digitalization technologies, mainly additive manufacturing, have enabled the synthesis of materials with tailored properties and functionalities. Joining dissimilar metals to attain compositional grading is a relatively unexplored research area and holds great promise for engineering applications.

Evaluation of Biotechnological Active Peptides Secreted by with Potential Skin Benefits.

Biotechnological active peptides are gaining interest in the cosmetics industry due to their antimicrobial, anti-inflammatory, antioxidant, and anti-collagenase (ACE) effects, as well as wound healing properties, making them suitable for cosmetic formulations. The antimicrobial activity of peptides (2-10 kDa) secreted by Ethanol-Red was evaluated against dermal pathogens using broth microdilution and challenge tests. ACE was assessed using a collagenase activity colorimetric assay, antioxidant activity via spectrophotometric monitoring of nitrotetrazolium blue chloride (NBT) reduction, and anti-inflammatory effects by quantifying TNF-α mRNA in lipopolysaccharides (LPS)-exposed dermal fibroblasts.

Polyhydroxyalkanoates production from cheese whey under near-seawater salinity conditions.

Treating saline streams presents considerable challenges due to their adverse effects on conventional biological processes, thereby leading to increased expenses in managing those side streams. With this in consideration, this study explores into the potential for valorizing fermented cheese whey (CW), a by-product of the dairy industry, into polyhydroxyalkanoates (PHA) using mixed microbial cultures (MMC) under conditions of near-seawater salinity (30 g/L). The selection of a PHA-accumulating MMC was successfully achieved using a sequential batch reactor operated under a feast and famine regime, with a hydraulic retention time of 14.

A conversational agent for enhanced Self-Management after cardiothoracic surgery.

Background: Enhanced self-management is crucial for long-term survival following cardiothoracic surgery.

Objectives: This study aimed to develop a conversational agent to enhance patient self-management after cardiothoracic surgery.

Methodology: The solution was designed and implemented following the Design Science Research Methodology.

High resolution analysis of proteolytic substrate processing.

Members of the widely conserved high temperature requirement A (HtrA) family of serine proteases are involved in multiple aspects of protein quality control. In this context, they have been shown to efficiently degrade misfolded proteins or protein fragments. However, recent reports suggest that folded proteins can also be native substrates.

Non-invasive and real-time monitoring of polyhydroxyalkanoates production using two-dimensional fluorescence spectroscopy.

Bioplastics are a sustainable and environmental-friendly alternative to the conventional petroleum-based plastics, namely due to their source (biobased) and due to their biodegradability or both. Polyhydroxyalkanoates (PHA) stand out among the bioplastics group by being intracellular biobased, biodegradable and biocompatible polymers. PHA production has been highly investigated during the last decades.

Assessment of oxidative stress biomarkers in Palaemon varians exposed to deep eutectic systems.

In recent years, there has been extensive research within the scientific community on deep eutectic systems due to their remarkable versatility in solubilizing diverse substances and serving as effective solvents in catalytic processes. While initially regarded as non-toxic, a comprehensive toxicological assessment is essential to comprehend their behavior within organisms. In this study, seven distinct systems, composed of N,N,N-triethyl-N-(2,3-dihydroxypropyl)ammonium chloride (N00Cl) and glycerol-derived ethers with alkyl chains of varying lengths (100, 200, 3F00, 300, 3i00, and 400), in a 1:2 molar ratio were investigated for their aquatic toxicity in shrimp (Palaemon varians).

Inferring Diagnostic and Prognostic Gene Expression Signatures Across WHO Glioma Classifications: A Network-Based Approach.

Tumor heterogeneity is a challenge to designing effective and targeted therapies. Glioma-type identification depends on specific molecular and histological features, which are defined by the official World Health Organization (WHO) classification of the central nervous system (CNS). These guidelines are constantly updated to support the diagnosis process, which affects all the successive clinical decisions.

Functional Assessment of >18 Years Old Patients at Internal Medicine Ward-Relationship with In-Hospital and 30-Day Mortality.

Objective: To evaluate the connection between the items included in the AVD-DezIs score (a questionnaire about basic and instrumental activities of daily living and other topics related to social and personal life) and in-hospital and 30-day mortality after discharge.

Methods: Prospective cohort study of hospitalizations in the Internal Medicine ward from 2014 to 2020, including >18 years old patients with a fully completed AVD-DezIs. To identify in-hospital and 30 days mortality, univariate and multivariate logistic models were applied, including random effects if justified.

Eddy Currents Probe Design for NDT Applications: A Review.

Eddy current testing (ECT) is a crucial non-destructive testing (NDT) technique extensively used across various industries to detect surface and sub-surface defects in conductive materials. This review explores the latest advancements and methodologies in the design of eddy current probes, emphasizing their application in diverse industrial contexts such as aerospace, automotive, energy, and electronics. It explores the fundamental principles of ECT, examining how eddy currents interact with material defects to provide valuable insights into material integrity.

Liquid-liquid phase inclusion bodies in acute and persistent parainfluenaza virus type 5 infections.

Cytoplasmic inclusion bodies (IBs) are a common feature of single-stranded, non-segmented, negative-strand RNA virus (Mononegavirales) infections and are thought to be regions of active virus transcription and replication. Here we followed the dynamics of IB formation and maintenance in cells infected with persistent and lytic/acute variants of the paramyxovirus, parainfluenza virus type 5 (PIV5). We show that there is a rapid increase in the number of small inclusions bodies up until approximately 12 h post-infection.

Current clinical framework on nitric oxide role in periodontal disease and blood pressure.

Objectives: In this review, we explored potential associations between NO and its derivatives, nitrite and nitrate, with periodontal and cardiovascular diseases, with special emphasis on the former. By providing a state-of-the-art and integrative understanding of this topic, we aimed to shed light on the potential role of these three nitrogen oxides in the periodontitis-hypertension nexus, identify knowledge gaps, and point out critical aspects of the experimental methodologies.

Materials And Methods: A comprehensive literature review was conducted on human salivary and plasma concentrations of nitrate and nitrite, and their impact on periodontal and cardiovascular health.

Impregnation of different lanthanides in a covalent organic framework (RIO-55) to a chemical determination of dopants substances.

Ionic Covalent Organic Frameworks are a special subgroup that has risen as promising materials for innovative applications. In parallel, some of the so-called Reticular Innovative Organic compounds (RIOs), which are ionic and non-ionic porous materials have been used with great versatility, for several purposes. In this work, the ionic dye-based RIO-55 was chosen to capture a series of lanthanides (Eu, Gd, Dy, and Tb) from water, observing their affinity with the lattice and the performance of the adsorbent.

Extraction of pesticides from soil using direct-immersion SPME LC-Tips followed by GC-MS/MS: Evaluation and proof-of-concept.

A new method was evaluated and developed for the analysis of pesticides in sandy-loam soil by direct-immersion solid phase microextraction (DI-SPME) followed by gas chromatography tandem-mass spectrometry (GC-MS/MS) determination. Ten pesticides were selected based on a literature survey of the compounds reported to be present in EU soils. The extraction was performed using SPME LC-Tips, a new SPME configuration with the coated fibers attached to a disposable and easy-to-handle micropipette tip, which was immersed into a soil slurry made by the addition of an aqueous solution to the soil sample.

Effect of mono- and dinuclear thiosemicarbazone platinacycles in the proliferation of a colorectal carcinoma cell line.

Herein, we describe the synthesis and characterization of a series of thiosemicarbazone platinacycles. Their activity towards HCT116 and A2780 cancer cell lines as well as normal fibroblasts was explored and conclusions about the influence of their structures were drawn based on the results. Ligands L1-3, tetranuclear compounds L1-3, L1-3, and L1-L3, and phosphine derivatives, were deemed unpromising owing to their lack of activity.