5 results match your criteria: "Nouvel Hôpital Civil-Strasbourg University Hospital[Affiliation]"

Prospective cholestanol screening of cerebrotendinous xanthomatosis among patients with juvenile-onset unexplained bilateral cataracts.

Orphanet J Rare Dis

December 2022

Reference Center for Lysosomal Diseases, Neuro-Metabolism Unit, Neurology Department, Pitié-Salpêtrière University Hospital, APHP, 47-83 Boulevard de l'Hôpital, 75013, Paris, France.

Background: Cerebrotendinous xanthomatosis (CTX) is a rare genetic disorder related to CYP27A1 biallelic mutations, leading to decreased synthesis of bile acids and increased cholestanol. Juvenile bilateral cataracts are one of the most common findings in the disease, frequently occurring before the onset of neurological manifestations. While early treatment with chenodeoxycholic acid can prevent the onset of neurological impairment, poor awareness of CTX accounts for a markedly delayed diagnosis.

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Venous thromboembolism in non-critically ill patients with COVID-19 infection.

Thromb Res

September 2020

Division of Cardiovascular Medicine, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France; INSERM (French National Institute of Health and Medical Research), UMR 1260, Regenerative Nanomedicine, FMTS, Strasbourg, France. Electronic address:

Article Synopsis
  • VTE is a common issue among patients with COVID-19, affecting 17.0% of those studied in a single-center research.
  • The study found that not using thromboprophylaxis and having high white blood cell counts (leukocytosis) are significant risk factors for developing VTE.
  • Additionally, VTE is linked to poorer results during the patients' hospital stays.
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Objective: To reduce the iodine load required for CT Transcatheter Aortic Valve Replacement (TAVR) planning on a 320-row scanner by acquiring the two CT TAVR steps (ECG-gated aortic root CTA and non-gated aorto-ilio-femoral CTA) within a single contrast media bolus injection.

Methods: 50 consecutive patients (82.6±6.

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Objective: Current clinical classification of superficial femoral artery (SFA) occlusions as defined by TASC II guidelines is limited to length and calcifications analysis on 2D angiograms, while state-of-the-art cross-sectional imaging like computed tomography angiography (CTA) and magnetic resonance angiography (MRA) provides much more detailed anatomical information than traditional invasive angiography: quantitative morphological analysis of these advanced imaging techniques could therefore be the basis of a refined classification.

Methods And Results: Forty-six patients (65% men, 68±11.6 years) that underwent lower limb CTA were retrospectively included, totalizing 60 SFA occlusions.

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