45 results match your criteria: "Nottingham NHS Treatment Centre[Affiliation]"

Article Synopsis
  • Autofluorescence-Raman microspectroscopy (AF-Raman) is a fast, non-invasive technology that helps detect remaining basal cell carcinoma (BCC) in tissue specimens without the need for extensive sample preparation.
  • In a study involving 130 patients undergoing Mohs micrographic surgery, the AF-Raman tool correctly identified BCC margins with a sensitivity of 67% and specificity of 73%, indicating its potential effectiveness.
  • The method showed some limitations, such as false-negatives caused by occlusion or poor contact during measurement, but overall, it provides a promising approach for intraoperative evaluations of BCC excisions.
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Clinical integration of fast Raman spectroscopy for Mohs micrographic surgery of basal cell carcinoma.

Biomed Opt Express

April 2021

School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, United Kingdom.

We present the first clinical integration of a prototype device based on integrated auto-fluorescence imaging and Raman spectroscopy (Fast Raman device) for intra-operative assessment of surgical margins during Mohs micrographic surgery of basal cell carcinoma (BCC). Fresh skin specimens from 112 patients were used to optimise the tissue pre-processing and the Fast Raman algorithms to enable an analysis of complete Mohs layers within 30 minutes. The optimisation allowed >95% of the resection surface area to be investigated (including the deep and epidermal margins).

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A self-report questionnaire to detect hand dermatitis in nurses.

Occup Med (Lond)

December 2020

Occupational Health Service, Guy's and St Thomas' NHS Foundation Trust/Faculty of Life Sciences and Medicine, King's College London, London, UK.

Background: Hand dermatitis is highly prevalent among nurses due to their frequent exposure to wet work. Providing cost-effective dermatological health surveillance for this occupational group presents a challenge to health service providers.

Aims: To ascertain the predictive value of nurses' self-assessment of whether they had current hand dermatitis using a screening questionnaire when compared with the assessment made by a dermatologist of the nurses' hand photographs.

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Regarding: "A Challenging Defect of the Nasal Ala".

Dermatol Surg

July 2021

Department of Dermatology, Nottingham NHS Treatment Centre, Nottingham University Hospitals, Nottingham, United Kingdom.

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Background: Dermatological services in Laos, South East Asia are limited mainly to the capital and patch testing is currently not available, so no data exists regarding the common cutaneous allergens in this population.

Objectives: The aim of this study was to document common allergens in paediatric patients with atopic dermatitis attending the allergy clinic in the capital, Vientiane.

Patients/materials/methods: Fifty paediatric patients with atopic dermatitis were patch tested using TRUE Test® panels 1 to 3 (35 allergens).

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Background: Occupational hand dermatitis poses a serious risk for nurses.

Objectives: To evaluate the clinical and cost-effectiveness of a complex intervention in reducing the prevalence of hand dermatitis in nurses METHODS: This was a cluster randomized controlled trial conducted at 35 hospital trusts, health boards or universities in the UK. Participants were (i) first-year student nurses with a history of atopic conditions or (ii) intensive care unit (ICU) nurses.

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Background: Dermatological services in Laos, South East Asia are limited to the capital and patch testing is currently not available, so no data exists regarding the common cutaneous allergens in this population.

Objectives: The aim of this study was to document positive patch tests in medical students without evidence of contact dermatitis in Laos.

Patients/materials/methods: One hundred and fifty medical students were patch tested using TRUE Test® panels 1 to 3 (35 allergens).

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Consent must be undertaken prior to any dermatological procedure; however, in doing this, the clinician needs to ensure consent is valid and satisfies the principles of determining material risk. We aimed to assess variations in obtaining consent in the UK and understanding of material risk through a nationally distributed survey to members of the British Society for Dermatological Surgery and British Association of Dermatologists. Of 165 responses, we found that written consent was being obtained for all procedures in 73.

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Background: Although strategies have been developed to minimise the risk of occupational hand dermatitis in nurses, their clinical effectiveness and cost-effectiveness remain unclear.

Objectives: The Skin Care Intervention in Nurses trial tested the hypothesis that a behaviour change package intervention, coupled with provision of hand moisturisers, could reduce the point prevalence of hand dermatitis when compared with standard care among nurses working in the NHS. The secondary aim was to assess the impact of the intervention on participants' beliefs and behaviour regarding hand care, and the cost-effectiveness of the intervention in comparison with normal care.

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Objectives: We aimed to conduct a large audit of routine care for patients with ANCA-associated vasculitis.

Methods: We invited all 34 hospitals within one health region in England to undertake a retrospective case note audit of all patients newly diagnosed or treated with CYC or rituximab (RTX) for ANCA-associated vasculitis from April 2013 to December 2014. We compared clinical practice to the British Society for Rheumatology guidelines for the management of adults with ANCA-associated vasculitis and the use of RTX with the National Health Service (NHS) England commissioning policy and National Institute for Health and Care Excellence (NICE) technology appraisal.

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Background: Neck of femur fractures is the most common fractures associated with low-velocity injury in the elderly. Some patients may require further histological examination of the femoral head due clinical suspicion of malignance as a cause of fracture.

Objectives: To review whether standard screening question(s) could be used to identify patients that require histological examinations following neck of femur fracture.

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Background: The shoulder is the least constrained of all joints of the body and is more susceptible to injury including dislocation. The rate of recurrent instability following primary stabilization procedure at 10 years of follow-up ranged from 3.4 to 20%.

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