New Drug Treats Pediatric Achondroplasia.

The Food and Drug Administration has granted accelerated approval to vosoritide (Voxzogo) to treat children ages five years and older with achondroplasia who still have open epiphyses.Children prescribed vosoritide should have a meal and 240 to 300 mL of fluid in the hour prior to drug administration to prevent hypotensive episodes.

An Update of Nucleic Acids Aptamers Theranostic Integration with CRISPR/Cas Technology.

The clustered regularly interspaced short palindromic repeat (CRISPR)/Cas system is best known for its role in genomic editing. It has also demonstrated great potential in nucleic acid biosensing. However, the specificity limitation in CRISPR/Cas has created a hurdle for its advancement.

New Naloxone Concentration Treats Opioid Overdose.

The Food and Drug Administration has approved another injectable form of naloxone in the effort to control opioid deaths. Zimhi is a single-dose prefilled syringe containing 5 mg/0.5 mL of naloxone.

FDA Warns Against Using Needle-Free Injection Devices For Dermal Fillers.

The Food and Drug Administration (FDA) has issued a safety communication to warn the public and health care professionals not to use needle-free devices for injection of dermal fillers. These devices are not approved by the FDA. FDA-approved dermal fillers are for prescription use only with a syringe and either a needle or cannula.

A Systematic Review of Global Health Assessment for Education in Healthcare Professions.

Objective: Emphasis on global health education is growing, with schools/colleges developing relevant courses, areas of concentration, and other didactic content. Organizations such as the Consortium of Universities for Global Health (CUGH) provide guidance for competencies in global health, but evaluation strategies are lacking. Accordingly, the purpose of this study was to identify methods and tools utilized to assess knowledge, skills, and attitudes in global health courses for health science students.

Galactagogues and Lactation: Considerations for Counseling Breastfeeding Mothers.

Development of a milk supply is a complex process that is not always understood by women who are breastfeeding. Galactagogues are substances commonly used by breastfeeding women who perceive that they have an insufficient milk supply. They can be herbal substances or pharmaceuticals.

Systematic Review of Predictors of Success for the North American Pharmacist Licensure Examination.

Studies have examined possible predictors of success on the North American Pharmacist Licensure Examination (NAPLEX). This systematic review investigated the literature on potential predictors of success on the NAPLEX. Articles were included in the review if they studied student characteristics and academic performance as independent variables and NAPLEX scores and/or pass rates as an outcome.

New Drug Treats Cervical Cancer.

Tisotumab vedotin-tftv (Tivdak) has received accelerated approval to treat adults with recurrent or metastatic cervical cancer with disease progression on or after chemotherapy.Ocular adverse effects occurred in 60% of patients in clinical trials. To minimize this risk, nurses should follow the guidelines for premedication and required eye care.

New Indication for Cabozantinib.

Cabozantinib (Cabometyx) is now approved to treat locally advanced or metastatic differentiated thyroid cancer that has progressed following prior vascular endothelial growth factor receptor-targeted therapy.

New Indication for Ruxolitinib.

The kinase inhibitor ruxolitinib (Jakafi) is now approved to treat chronic graft-vs-host disease.

A study of students' use of restraint systems in school transportation services in primary and secondary schools in northern Iran: an observational study.

Background: Traffic accidents are one of the leading causes of death and severe injury among child occupants of vehicles in most countries. This has led to the consideration of how to use restraint systems for students in school buses. The purpose of the present study was to determine the percentage of students' use of restraint systems in school transportation services in 2020.

Utilization of an emotional intelligence workshop to enhance student pharmacists' self-awareness.

Background And Purpose: This study evaluated the impact of an emotional intelligence (EI) workshop as a tool to improve student pharmacists' self-awareness. The primary objectives were to assess the change in student pharmacists' self-awareness as measured by the Self-Awareness Outcomes Questionnaire (SAOQ) and identify trends in their self-reflection.

Educational Activity And Setting: A four-hour EI workshop was delivered in a first-year required student pharmacist leadership course.

Design and implementation of a pilot student wellness program at a school of pharmacy.

Background And Purpose: In response to concerns about student stress and well-being, a volunteer wellness task force was formed to promote a culture of wellness at the school of pharmacy (SOP). The purpose of this paper is to describe the development and implementation of this pilot wellness program.

Educational Activity And Setting: A task force was formed to design and implement a pilot wellness program for pharmacy students.

New Indications and Approvals for Anticancer Drugs.

Several anticancer drugs have received new indications; new drug approvals; or regular approvals to replace previous accelerated, conditional approvals.

Rethinking the Pharmacy Workforce Crisis by Exploring Unconventional and Emerging Career Pathways and Training.

Given the limited availability of conventional pharmacy positions, pharmacy programs face a challenge in ensuring that all graduates obtain jobs that fulfill their goals and ambitions. Thus, it is imperative to explore and discuss unconventional but promising positions, specifically regarding their availability and needs. In exploring these positions, it is important to recognize technical and nontechnical skill sets that pharmacy graduates possess at graduation, identify unique pathways to help students explore job alternatives, and educate faculty and students about employment opportunities beyond the traditional setting if desired or necessary.

Evidence and Strategies for Including Emotional Intelligence in Pharmacy Education.

This integrative review summarizes the literature addressing emotional intelligence among health care professionals and students to better define and incorporate it into the pharmacy curricula. Emotional intelligence is an essential attribute for relationship building, stress management, and self-regulation. Pharmacy students must develop and improve their emotional intelligence to support their development of successful relationships with patients, pharmacy colleagues, and other health care providers.

New Drug for Mismatch Repair Deficient Endometrial Cancer and Solid Tumors.

The Food and Drug Administration (FDA) has granted accelerated approval to dostarlimab-gxly (Jemperli) for the treatment of adults with mismatch repair deficient recurrent or advanced endometrial cancer and solid tumors.

New Type 2 Diabetes Drug AIMS to Reduce Risk of Diminished Kidney Function and Cardiovascular Complications.

Finerenone (Kerendia) has been approved to reduce the risk of sustained estimated glomerular filtration rate decline, end-stage kidney disease, cardiovascular death, nonfatal myocardial infarction, and hospitalization for heart failure in adults with chronic kidney disease associated with type 2 diabetes.

Statins No Longer Contraindicated in Pregnancy.

The labeling of statins has been revised to remove the contraindication for use during pregnancy.For a select few women at high risk for cardiovascular events, statins may provide more benefit than risk, even during pregnancy. Most women do not have this high risk, however, and should still avoid statins during pregnancy.

Eua for Regen-Cov Now Includes COVID-19 Postexposure Prophylaxis.

The emergency use authorization for REGEN-COV (a combination of two monoclonal antibodies, casirivimab and imdevimab) has been revised to include postexposure prophylaxis of COVID-19 in adults and children 12 years of age and older who, if they become COVID-19 positive, are at high risk for severe disease.Prophylaxis with REGEN-COV is not a substitute for vaccination against COVID-19.

Sex and Age Differences in Activity Budgets in a Population of Captive African Penguins (Spheniscus demersus).

The African penguin () is an endangered species that continues to experience population decline. Understanding the behavior of this species is a critical step in the conservation efforts to prevent their extinction. A comprehensive activity budget of this species has yet to be conducted in any captive population, which are critical for the Species Survival Plan (SSP) breeding programs.

Controversial Approval of New Drug to Treat Alzheimer's Disease.

Aducanumab (Aduhelm), the first new drug to treat Alzheimer's disease since 2003, has received accelerated approval from the Food and Drug Administration (FDA).This drug's approval has been highly contentious in the medical and scientific community owing to contradictory study findings and the FDA's advisory panel not recommending its approval.

Rural young males' acceptance & receptiveness to technology-based interventions for dating violence prevention: A qualitative descriptive study.

Introduction: Rural youth are twice as likely as urban youth to experience some forms of teen dating violence (TDV), and significant barriers to accessing support services for physical, psychological, sexual violence. However, rural youth remain understudied and undersampled. Rural young men, in particular, are at risk for experiencing or perpetrating dating violence influenced by regional and sociocultural risk factors that promote male supremacy ideals while also impeding male help-seeking.