11,420 results match your criteria: "Nosocomial Pneumonia"
BMJ Open Qual
December 2024
Department of Microbiology, All India Institute of Medical Sciences, Patna, Bihar, India.
Background: Ventilator-associated pneumonia (VAP) is a prevalent nosocomial infection in the intensive care unit (ICU), significantly increasing patient morbidity, mortality, and healthcare costs. Effective management is essential, particularly in the context of antimicrobial resistance and the frequent use of antibiotics in ICUs.
Methods: This prospective pre-post interventional study was conducted in the medical ICU of a tertiary care centre, over 6 months.
Arch Orthop Trauma Surg
December 2024
Department of Orthopedic Surgery, University of Miami Miller School of Medicine, NW 14th Street, Miami, FL, 33136, USA.
Objective: What is the effect of surgical or conservative treatment on the in-hospital outcomes of patients with combined fractures of the clavicle and ribs?
Design: Retrospective cohort study.
Setting: Two level-1 trauma centers and academic teaching hospitals in Boston, Massachusetts.
Patients: All adult patients with a clavicle fracture and ≥3 rib fractures admitted from 2016 to 2021.
Eur J Intern Med
December 2024
Unit of Geriatrics, Department of Internal Medicine, Azienda Ospedaliera S. Giovanni-Addolorata, Rome, Italy.
Background: High-income countries are currently decreasing length of hospital stay (LOS), with the aim of improving resource utilization. Little is known about the contribution of LOS to short-term post-discharge mortality in older patients with pneumonia.
Aim: to identify factors independently associated with LOS and to determine whether LOS predicts 3-month post-discharge death in older patients hospitalized for pneumonia.
Einstein (Sao Paulo)
December 2024
Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Objective: To evaluate the risk factors for healthcare-related infections during the COVID-19 pandemic in intensive care units, to investigate the impact of COVID-19 on Central Line-Associated Bloodstream Infection, Catheter-Associated Urinary Tract Infection, and ventilator-associated pneumonia, and to describe healthcare-associated infections in the waves of the COVID-19 pandemic.
Methods: This nested case-control study was conducted in a 137-bed adult medical/surgical intensive care unit at a private hospital in São Paulo, Brazil, between January 11, 2019, and May 21, 2022. Case patients were identified using the Nosocomial Infection Control Committee database and control patients were identified using the intensive care unit's EPIMED system.
PeerJ
December 2024
Department of Critical Care Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Objective: To evaluate the efficacy and safety of prophylactic nebulized antibiotics in preventing intensive care unit (ICU)-acquired pneumonia through a meta-analysis.
Methods: Randomized controlled trials (RCTs) investigating the potential reduction in the incidence of ICU-acquired pneumonia through prophylactic nebulized antibiotics were collected by searching the PubMed, Embase, and Cochrane Library databases from their inception to January 23, 2024. The primary endpoint was the incidence of ICU-acquired pneumonia, while the secondary endpoints included mortality, length of ICU stay, mechanical ventilation days, and nebulization-related side effects.
Diagnostics (Basel)
December 2024
Institute of Forensic Medicine Timisoara, 300041 Timisoara, Romania.
Background: Patients with traumatic injuries often represent the best hosts for healthcare-associated infections, especially pneumonia or bronchopneumonia. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic raised serious problems in the diagnosis and treatment of patients that had a SARS-CoV-2 infection and associated nosocomial bacterial bronchopneumonia. In forensic medicine, these aspects need to be considered when establishing the cause of death and the distinction between the two types of bronchopneumonia is of particular importance.
View Article and Find Full Text PDFInt J Infect Dis
December 2024
Department of Pulmonary and Critical Care Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. Electronic address:
Objectives: Imipenem/cilastatin/relebactam (IMI/REL) is a β-lactam/β-lactamase inhibitor combination effective against gram-negative pathogens. Efficacy and safety of IMI/REL were studied in critically ill adults with hospital-acquired bacterial pneumonia (HABP) or ventilator-associated bacterial pneumonia (VABP).
Methods: In this phase III, double-blind, multinational, randomized trial (NCT03583333), adults with HABP/VABP were randomized 1:1 to receive intravenous IMI/REL (500 mg/250 mg) or piperacillin/tazobactam (PIP/TAZ; 4000 mg/500 mg) every 6 h for 7-14 days.
Pneumologie
December 2024
EVK Hattingen, Praxis für Logopädie, Hattingen, Deutschland.
Aspiration pneumonia (AP) may present as gross aspiration of large gastric contents or as a consequence of silent aspiration of contaminated oropharyngeal secretions.AP due to silent aspiration is caused by dysphagia and, in some instances, impaired cough reflex. Factors favouring the development of pneumonia include advanced age as well as severe comorbidity and impaired functional status.
View Article and Find Full Text PDFPLoS One
December 2024
Department of Acute and Critical Care Nursing, School of Nursing, Sapporo City University, Sapporo, Hokkaido, Japan.
Oral hygiene care is important for ventilator-associated pneumonia prevention. However, the optimal oral hygiene care approach remains unclear. A network meta-analysis was conducted to compare the efficacy of various oral hygiene care methods for ventilator-associated pneumonia prevention in critically ill patients, and the methods were ranked.
View Article and Find Full Text PDFFront Pharmacol
November 2024
Center for Evidence-Based Medicine, Affiliated Hospital of Chengdu University, Chengdu, Sichuan, China.
Objective: This study aims to conduct a systematic review and network meta-analysis to evaluate the efficacy and safety of specific corticosteroids, including but not limited to hydrocortisone, methylprednisolone, prednisolone, and dexamethasone, in the treatment of severe community-acquired pneumonia (SCAP). Efficacy will be assessed using specific outcomes, such as 30-day mortality and the requirement for mechanical ventilation. Safety evaluations will include adverse events like gastrointestinal bleeding and healthcare-associated infections.
View Article and Find Full Text PDFJ Antimicrob Chemother
December 2024
Department of Medicine, Yale School of Medicine, New Haven, CT, USA.
Background: Empiric antibiotics active against Pseudomonas aeruginosa are recommended by professional societies for certain infections and are commonly prescribed for hospitalized patients. The effect of this practice on mortality is uncertain.
Methods: A systematic literature search was conducted using Embase, Medline, PubMed, Web of Science, Cochrane, Scopus and Google Scholar from earliest entry through 9 October 2023.
Cureus
November 2024
Nephrology, SRM Medical College Hospital and Research Centre, Chennai, IND.
Catheter-related bloodstream infections (CRBSIs) add to the morbidity and mortality of hemodialysis patients. is an extremely resistant, gram-negative, non-lactose-fermenting nosocomial bacterium that contributes significantly to mortality and morbidity. This bacterium is predominantly associated with community-acquired pneumonia, bacteremia, eye afflictions, biliary sepsis, urinary tract infection, skin and soft tissue infection, and very rarely chronic enteritis with colonic ulcers.
View Article and Find Full Text PDFInfection
December 2024
Infectious Diseases Unit, Department of Clinical and Experimental Medicine, Azienda Ospedaliera Universitaria Pisana, University of Pisa, Pisa, Italy.
Purpose: To describe the clinical characteristics and outcomes of patients with nosocomial pneumonia (NP) caused by carbapenem-resistant Gram-negative bacilli (CR-GNB) and to compare them to patients with NP caused by carbapenem-susceptible (CS)-GNB.
Methods: Prospective observational multicenter study including patients with bacteremic NP caused by GNB from the ALARICO Network (June 2018-January 2020). The primary outcome measure was 30-day mortality.
Infect Drug Resist
November 2024
Department of Nosocomial Infection Management, Ganzhou People's Hospital, Ganzhou, Jiangxi, People's Republic of China.
PLoS Negl Trop Dis
December 2024
Department of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, China.
Turk Kardiyol Dern Ars
December 2024
Almazov National Medical Research Centre, St. Petersburg, Russia.
Afr J Infect Dis
October 2024
Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
J Infect Dev Ctries
October 2024
Department of Infectious Diseases and Clinical Microbiology, Izmir Katip Celebi University, Izmir, Turkiye.
Semin Respir Crit Care Med
December 2024
CIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain.
Cureus
October 2024
Department of Microbiology, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, IND.
Microb Pathog
January 2025
Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, School of Basic Medical Sciences, Guangdong Pharmaceutical University, 280 Wai Huan Dong Road, Guangzhou Higher Education Mega Center, Guangzhou, 510006, PR China; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, PR China. Electronic address:
J Infect
December 2024
Big Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, UK; The National Institute for Health Research Oxford Biomedical Research Centre, University of Oxford, Oxford, UK; Department of Infectious Diseases and Microbiology, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK; The National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance at the University of Oxford, Oxford, UK. Electronic address:
Sci Rep
November 2024
Faculty of Medicine, Clinical Department of Anesthesiology and Intensive Therapy, Wroclaw Medical University, Wroclaw, 50-556, Poland.
Diagn Microbiol Infect Dis
February 2025
Department of Infectious Diseases, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China. Electronic address:
J Clin Med
November 2024
Operative Research Unit of Anesthesia and Intensive Care, Fondazione Policlinico Universitario Campus Bio-Medico, 00127 Roma, Italy.