Clinical Outcomes of a Modified Technique Combining Submucosal Turbinectomy and Extended Neural Targeting in Chronic Rhinitis Management.

Background/aim: This study evaluated the outcomes of combining submucosal turbinectomy with extensive disruption of the pterygopalatine ganglionic efferent nerve fibers through a minimucosal incision in patients with intractable rhinitis, irrespective of their dependency on the posterior nasal nerve.

Patients And Methods: We describe an endoscopic extended neurectomy procedure performed via a minimucosal pocket. The primary outcome measures included the Total Nasal Symptom Score (TNSS), Visual Analog Scale (VAS) score, and runny nose and nasal obstruction subdomains of the Sino-Nasal Outcome Test-22 (SNOT-22), which were assessed pre-procedure and at 3 and 6 months post-procedure.

Self-reported chronic rhinosinusitis diagnoses and symptoms in World Trade Center-exposed and non-World Trade Center-exposed United States firefighters.

Background: Greater World Trade Center (WTC) exposure levels have been associated with chronic rhinosinusitis (CRS) diagnoses and symptoms. We aimed to determine whether self-reported CRS is elevated in WTC-exposed Fire Department of the City of New York (FDNY) firefighters when compared with non-WTC-exposed/non-FDNY firefighters and with the general population.

Methods: The study included male WTC-exposed (N = 7840) and non-WTC-exposed (N = 2771) firefighters who were employed on 9/11/2001 and later completed a health survey.

Skin necrosis after autologous fat grafting for augmentation rhinoplasty: a case report and review of the literature.

Background: Autologous fat transplantation has gained increasing attention in the field of cosmetic surgery. However, a series of complications can occur after fat transplantation.

Case Presentation: A 24-year-old woman presented at our Hospital with nasal skin necrosis and ulceration.

Adherence to implementing physical distancing and other COVID-19 preventive measures and its barriers among adults in Arba Minch town, Southwest Ethiopia: A lesson learned from the pandemic.

Background: Globally, as of March 2024, the number of confirmed Coronavirus Disease 2019 (COVID-19) cases and deaths were over 774 million and seven million, respectively. Since there are no proven treatment in place against the disease, controlling strategy mainly rely on preventive measures. However, data on the extent of implementing physical distancing and other preventive measures during the pandemic of COVID-19 were inadequate in the study setting.

Matrix metalloproteinase-12 by M2 macrophages induced epithelial to mesenchymal transition in chronic rhinosinusitis with nasal polyps.

Th2 inflammation and epithelial-mesenchymal transition (EMT) play crucial roles in the pathophysiology of chronic rhinosinusitis with nasal polyps (CRSwNP). This study aimed to investigate the hypothesis that MMP-12, produced by M2 macrophages, induces EMT in nasal epithelial cells, thereby contributing to airway inflammation and remodeling in CRSwNP. The expression levels of MMP-12 were measured by RT-PCR in CRS nasal mucosa and THP-1 cells.

Profiling endogenous airway proteases and antiproteases and modeling proteolytic activation of Influenza HA using in vitro and ex vivo human airway surface liquid samples.

Imbalance of airway proteases and antiproteases has been implicated in diseases such as COPD and environmental exposures including cigarette smoke and ozone. To initiate infection, endogenous proteases are commandeered by respiratory viruses upon encountering the airway epithelium. The airway proteolytic environment likely contains redundant antiproteases and proteases with diverse catalytic mechanisms, however a proteomic profile of these enzymes and inhibitors in airway samples has not been reported.

Computing nasalance with MFCCs and Convolutional Neural Networks.

Nasalance is a valuable clinical biomarker for hypernasality. It is computed as the ratio of acoustic energy emitted through the nose to the total energy emitted through the mouth and nose (eNasalance). A new approach is proposed to compute nasalance using Convolutional Neural Networks (CNNs) trained with Mel-Frequency Cepstrum Coefficients (mfccNasalance).

Retrospective evaluation of computed tomographic-guided Tru-Cut biopsies in 16 dogs and 14 cats with nasal cavity mass lesions.

Background: Approximately 80% of nasal masses in dogs and 91% of nasal masses in cats are reported to be malignant, but the currently reported diagnostic rate of neoplasia is 54% using blind or rhinoscopic biopsy techniques.

Hypothesis/objectives: Describe the technique of computed tomography (CT)-guided Tru-Cut (Tru-Cut biopsy needle, Merit Medical Systems, Utah, USA) nasal biopsies in cats and dogs to determine the diagnostic rate of neoplasia on the first round of sampling and to evaluate the safety of the technique.

Animals: Thirty client-owned animals, 16 dogs and 14 cats, that had CT-guided nasal biopsies performed to investigate nasal masses.

A deep learning based smartphone application for early detection of nasopharyngeal carcinoma using endoscopic images.

Nasal endoscopy is crucial for the early detection of nasopharyngeal carcinoma (NPC), but its accuracy relies heavily on the clinician's expertise, posing challenges for primary healthcare providers. Here, we retrospectively analysed 39,340 nasal endoscopic white-light images from three high-incidence NPC centres, utilising eight advanced deep learning models to develop an Internet-enabled smartphone application, "Nose-Keeper", that can be used for early detection of NPC and five prevalent nasal diseases and assessment of healthy individuals. Our app demonstrated a remarkable overall accuracy of 92.

Changes in relative peripheral refraction after implantable collamer lenses implantation.

Purpose: This study aimed to measure the changes in refraction difference value (RDV) in different parts of the retina before and after implantable collamer lenses (ICL) surgery.

Design: Prospective study.

Methods: This study included 40 eyes of 40 patients who underwent ICL implantation for myopia.

0.5T MRI as a competitor to CT for sinus imaging.

The goal of this study was to determine how radiologists' rating of image quality when using 0.5T Magnetic Resonance Imaging (MRI) compares to Computed Tomography (CT) for visualization of pathology and evaluation of specific anatomic regions within the paranasal sinuses. 42 patients with clinical CT scans opted to have a 0.

Detection of the methicillin-resistant gene encoding in nasal swabs of cats in Surabaya, Indonesia.

Background: The most susceptible group of people to spread methicillin-resistant (MRSA) among domestic cats is their owners' relatives.

Aim: Considering the aforementioned, research at the Surabaya City Animal Hospital is necessary to determine whether the A gene may be detected in cat nasal swabs.

Methods: Samples were taken using a sterile cotton swab, and the transport medium was buffered peptone water.

Description of tissue profiles, thalamic location, and recommended penetrating captive bolt placement in cadaver heads from domesticated 24- to 48-mo-old male yaks ().

Yaks are a domesticated species utilized for meat, fiber, and transportation in many countries. In the United States, yak meat is growing in popularity due to its classification as a "healthy" meat. Penetrating captive bolt (PCB) is an approved method of preslaughter stunning and euthanasia for cattle.

A Rare Case of Nasal myiasis following Kidney Transplantation.

In this case report, we present a 63-year-old man with a history of diabetes mellitus and kidney transplantation who was diagnosed with nasal myiasis. The patient presented with symptoms of nasal myiasis infestation, including epistaxis, nasal obstruction, nasal discharge, and the presence of larvae. The patient had risk factors for poor wound healing, such as hyperglycemia, and the presence of diabetes mellitus, hypertension, and kidney transplantation indicated the presence of predisposing factors for myiasis.

Sinonasal Leiomyoma: A Case Report and a Review of the Literature.

Sinonasal leiomyoma is an exceptionally rare neoplasm arising from smooth muscle cells within the sinonasal tract. This abstract presents a case study of a 43-year-old male patient diagnosed with sinonasal leiomyoma, a distinctive and challenging entity in otolaryngology. The patient presented with a complex clinical history, including a 2-year interval between initial evaluation and definitive diagnosis.

Economic Burden of Multimorbidity and Polypharmacy Among Geriatric Patients: A Single-Center Experience From Odisha, India.

Background Multimorbidity and polypharmacy are common in older adults and pose a considerable challenge to the health and social care system. They are complex and interrelated concepts in geriatric care that require early detection and patient-centered shared decision-making by multidisciplinary, team-led comprehensive geriatric assessment (CGA) across all health and social care settings. The primary objective of this study is to investigate the economic burden of multimorbidity and polypharmacy among geriatric patients.

Utilization of Integrated Ayushman Bharat - Pradhan Mantri Jan Arogya Yojana and Mahatma Jyotirao Phule Jan Arogya Yojana at a Tertiary Care Center in Solapur, India: An Epidemiological Study.

Background: The Integrated Ayushman Bharat - Pradhan Mantri Jan Arogya Yojana (AB-PMJAY) and Mahatma Jyotirao Phule Jan Arogya Yojana (MJPJAY) is a public-funded health insurance scheme in the state of Maharashtra. The scheme provides end-to-end cashless services for identified diseases through a network of hospitals from both the government sector as well as the private sector, covered under the scheme. AB-PMJAY is a scheme of the government of India.

A Rare Presentation of Synchronous Thyroglossal Cyst and Branchial Cyst in an Adult Male Patient.

The most common congenital cervical masses are thyroglossal cysts followed by branchial cleft anomalies. However, their synchronous presentation is uncommon. A man in his early thirties visited our ear, nose, and throat (ENT) outpatient department (OPD) with complaints of a three-month history of right-side neck swelling.

Association Between Caregiver Burden and Treatment Adherence in Japanese Children With Allergic Rhinitis Receiving Sublingual Immunotherapy.

Background: Sublingual immunotherapy (SLIT) leads to the long-term remission of allergic rhinitis and requires long-term daily adherence. There are limited studies on the treatment burden or satisfaction of SLIT among caregivers of children treated using SLIT. We aimed to evaluate the association between the treatment burden and satisfaction for pediatric allergic rhinitis caregivers and the clinical factors of their children's SLIT.

From Quackery to Super-Specialization: A Brief History of Aesthetic Surgery.

From time immemorial, human beings have always tried to decorate themselves to look more beautiful and attractive to an onlooker, in turn improving their own self-esteem. Thus, in India and in Egypt, written thousands of years ago, mention a variety of cosmetics being used for the same. However, operative interventions were mainly reconstructive and any improved aesthetics was a by-product only (e.

A new scoring in differential diagnosis: multisystem inflammatory syndrome or adenovirus infection?

Background/aim: Differentiating multisystem inflammatory syndrome in children (MIS-C) from adenovirus infection (AI) can be challenging due to similar clinical and laboratory findings. This study aimed to identify distinguishing characteristics and develop a scoring system to facilitate accurate diagnosis.

Materials And Methods: A comprehensive review of medical records was undertaken for 108 MIS-C patients and 259 patients with confirmed AI.

[Issues of auditory implant in children with cochlear nerve deficiency].

Cochlear nerve deficiency（CND） is a rare inner ear malformation characterized by a hypoplastic or absent cochlear nerve, resulting in variable hearing loss or total deafness, depending on the quantity of nerve fibers present. About 18% of congenital hearing loss are associated with CND. It is a disease of uncertain cause.