Rhinorrhea Recurrence After Posterior Nasal Nerve Cryoablation: A Multicenter Cohort Study.

Background: Posterior nasal nerve (PNN) cryoablation improves chronic rhinitis (CR) symptoms in 70-80% of cases, including clear thin rhinorrhea (CTR). This study's purpose was to determine time to and degree of CTR recurrence following cryoablation.

Methods: A multicenter retrospective cohort study was conducted on patients who underwent PNN cryoablation to treat CR-related CTR refractory to ipratropium bromide nasal spray (IBNS).

A Rare Case of a Primary Non-parasitic Splenic Cyst Removed via Laparoscopic Intervention.

Splenic cysts are differentiated into primary and secondary cysts based on epithelial lining. Primary non-parasitic epithelial splenic cysts are extremely rare. We report a case of a 24-year-old male with left hypochondrial swelling with no history of abdominal trauma.

Postoperative dizziness after cochlear implant surgery: can it be caused by air?

Objectives: Multiple studies have described the onset and variable incidence of postoperative acute vertigo following cochlear implant (CI) surgery. However, postoperative imaging has not yet been specifically evaluated with special focus on vertigo. The aim of this study is to assess the incidence and causes of new-onset, acute postoperative vertigo following CI surgery using cone beam computed tomography (CBCT).

Nasal Rehabilitation in a Patient After Basal Cell Carcinoma and Radiotherapy: A Case Report.

Nasal rehabilitation following basal cell carcinoma (BCC) and radiotherapy presents significant challenges due to the intricate balance between aesthetic and functional restoration. This case report discusses the rehabilitation of a 73-year-old male who underwent surgical excision and radiotherapy for BCC located on the left ala of the nose. Post-treatment, the patient experienced dissatisfaction with his facial appearance, negatively impacting his quality of life.

The Rodent Electronic Nicotine Delivery System: Description and Validation of an Apparatus for Nose-Only E-Cigarette Aerosol Inhalation in Freely Moving Rats.

Tobacco use is the leading cause of death globally and in the U.S. After decades of decline, driven by decreases in combusted tobacco use, nicotine product use has increased due to Electronic Nicotine Delivery Systems (ENDS), also known as e-cigarettes or vapes.

MultiSpace Deep Fascial Infection in the Head and Neck Patient Complicated with Guillain-Barre Syndrome: Case Report with a Literature Review.

Guillain-Barre syndrome (GBS) is the most prevalent and severe form of acute paralytic neuropathy, commonly triggered by infections and characterized by an abnormal autoimmune response. Reports of multispace deep fascial infection (DFI) in the head and neck complicated by GBS are exceedingly rare. We report a 69-year-old woman with DFI who developed postoperative limbs weakness.

PEGylated solid lipid nanoparticles for the intranasal delivery of combination antiretroviral therapy composed of Atazanavir and Elvitegravir to treat NeuroAIDS.

Intranasal drug administration offers a promising strategy for delivering combination antiretroviral therapy (cART) directly to the central nervous system to treat NeuroAIDS, leveraging the nose-to-brain route to bypass the blood-brain barrier. However, challenges such as enzymatic degradation in the nasal mucosa, low permeability, and mucociliary clearance within the nasal cavity must first be addressed to make this route feasible. To overcome these barriers, this study developed solid lipid nanoparticles (SLNs) with varying PEGylation levels (0 %, 5 %, 10 %, and 15 % w/w of PEGylated lipid), co-encapsulated with Elvitegravir (EVG) and Atazanavir (ATZ) as an integrase and protease inhibitor, respectively.

Impact of sinus surgery on nasal discharge in chronic rhinosinusitis: A systematic review and meta-analysis.

Background: Nasal discharge is one of the cardinal symptoms of chronic rhinosinusitis, impacting over 50% of patients. For patients with symptoms refractory to standard medical therapy, endoscopic sinus surgery is an option. The objective of this study is to characterize how nasal discharge improves after surgery in patients with chronic rhinosinusitis.

Drought responsive transcriptional regulations and expressional marker genes of Japanese cedar, Cryptomeria japonica (L.f.) D.Don.

The selection of plant genotypes characterized by wellness and stable growth under drought-stress conditions amid ongoing climate change is an important challenge in forest tree breeding. The introduction of molecular markers will enable efficient selection of breeding materials that are resistant to drought stress in forest trees as well as in crop species. Japanese cedar, Cryptomeria japonica, the most dominant forest species in Japan, grows well on mesic sites and is characterized by intraspecific variation in its drought-stress response.

Gene Analysis of Biostimulators: Poly-L-Lactic Acid Triggers Regeneration While Calcium Hydroxylapatite Induces Inflammation Upon Facial Injection.

Background: Injectable biostimulator treatments stimulate endogenous collagen in aging skin, but whether they act through similar pathways is unknown. This study evaluates two biostimulatory agents' effects on genes, expressed proteins, and respective pathways as potential aging biomarkers and treatment outcomes.

Methods: This 13-week, randomized, single-center, comparative study compared volume change and gene expression stimulated by poly-L-lactic acid (PLLA-SCATM) and calcium hydroxylapatite (CaHA-R) via punch biopsy in the nasolabial fold (NLF).

Use of Bovine Xenografts for Nasal Defects After Mohs Micrographic Surgery.

Background: Nasal defects after skin cancer excision can often be healed by second intention in certain circumstances.

Objective: We aim to demonstrate the utility of bovine collagen xenografts in supplementing second-intention healing of a variety of nose surgical defects.

Results: Thirty-nine patients underwent Mohs micrographic surgery of the nasal tip (33%), ala (23%), dorsum (31%), sidewall (10%), and root (3%) with the application of bovine collagen xenograft.

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis.

Acupuncture Point Embedding Therapy is a comprehensive treatment method that combines modern biomaterials with acupuncture techniques. Acupoint catgut embedding (ACE) not only avoids the adverse reactions associated with Western medicine but also incorporates the benefits of traditional acupuncture, extending the duration of its therapeutic effects. Allergic rhinitis (AR) is a condition known for its challenging treatment and tendency to persist.

Acute Focal Bacterial Nephritis and Bacteremia Due to Staphylococcus simulans Following an Upper Respiratory Infection in a Child: A Case Report.

Coagulase-negative (CoNS) is a rare cause of UTIs in children and is often regarded as a contaminant in urine samples. We report a case of acute focal bacterial nephritis (AFBN) and bacteremia caused by following an upper respiratory infection in a pediatric patient. The patient, a four-year-old girl, presented with fever, cough, and a runny nose two days before being referred to our hospital due to persistent fever and poor oral intake.

Phaeohyphomycosis of the Eyelid: A Case Report.

Phaeohyphomycosis is a fungal infection caused by dematiaceous fungi that presents as a superficial, cutaneous, subcutaneous, or systemic infection. Subcutaneous phaeohyphomycosis is the most common manifestation and presents as a subcutaneous nodule or cystic lesions and abscesses. It usually results from traumatic implantation of the saprophytic fungus from soil and vegetative matter; therefore, the commonest sites of infection are the extremities.

A cross-sectional study to correlate nasal profile and chin position with cephalometric lip profile.

Objective: To determine the effect of the nose and chin on the cephalometric lip profile.

Methods And Material: The pre-treatment lateral cephalograms of 177 adult patients with no history of orthodontic treatment were manually traced. The sample size was divided into three vertical and horizontal groups using angle ANB and MMA to assess the difference in nose and chin forms.

Decoding the effects of brining time on the sensory quality, physicochemical properties and flavor characteristics of marinated grass carp meat.

This study aimed to explore the effects of different brining times on the sensory, physicochemical properties, and volatile organic compounds (VOCs) of marinated grass carp (MGC). The results showed that different brining time changed the sensory quality, color and texture. The moisture content increased significantly with the extension of brining time, while the salt content, protein content, thiobarbituric acid reactive substances (TBARS), and total volatile basic‑nitrogen (TVB-N) decreased ( 0.

Effects of exogenous selenium application on quality characteristics, selenium speciation, and in vitro bioaccessibility of rice pancakes.

Selenium is an essential trace element for human health. To date, a hotspot of functional foods is strengthening the content of organic Se in food using biological Se enrichment. Herein, Se-enriched rice pancakes were produced by directly adding different sodium selenite concentrations into the fermentation process.

Quantification of intraepithelial canine melanocytes in different somatic areas.

Background: In humans, the presence of an even distribution of melanocytes within the epidermal basal layer allows for uniform pigmentation in healthy and young individuals. Moreover, despite high variability in skin colours and tones, interindividual melanocyte density variability is low. However, dogs display a high intraindividual pigmentary variability in different anatomical areas.

Detection and analysis of enzootic nasal tumor virus 2 in China.

Enzootic nasal tumor virus 2 (ENTV2), the etiologic agent of enzootic nasal adenocarcinoma (ENA) in goats, is highly prevalent in China and causes significant economic losses to the goat industry. Here we describe the occurrence of ENA on a Dazu black goat farm in Chongqing City. At autopsy, nasal cavity masses were observed within the nose of an affected goat; histologically, the tumor was a nasal adenocarcinoma.

Clinical Presentation of Frontal Sinus Squamous Cell Carcinoma in the Dog and Response to Treatment With Radiation Therapy in Eight Dogs.

Primary frontal sinus squamous cell carcinoma (PFSSCC) represents a rare disease in dogs, and there is a general paucity of information in the current veterinary literature regarding its presentation and response to radiation therapy. The objective of this retrospective observational study was to describe a series of dogs diagnosed with PFSSCC and report their response to radiation therapy. Medical records of dogs with a diagnosis of PFSSCC were reviewed.

Diagnosis, treatment, surgical practices and review of the literature in rare coagulation factor deficiencies.

Background: Rare bleeding disorders (RBDs) include fibrinogen (Factor I), prothrombin (Factor II), Factor V(FV), combined Factor V and Factor VIII, Factor VII, Factor X, Factor XI, Factor XII, and Factor XIII deficiencies. This group accounts for 3-5% of all factor deficiencies. Different symptoms may occur, ranging from mild or moderate bleeding to serious and life-threatening bleeding, which may not be related to the factor level.