169,711 results match your criteria: "Nose & Throat Clinic[Affiliation]"

Purpose: The maxillary tuberosity, a critical anatomical landmark in dentistry and maxillofacial surgery, is burdened by terminological confusion. This inconsistency hampers clinical practice and communication across disciplines.

Method: Different resources were used to argue for the necessity of standardising the terminology related to maxillary tuberosity to enhance diagnostic precision and ultimately improve patient outcomes.

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Diagnostic Accuracy of Breath Tests to Detect Pulmonary Tuberculosis: A Systematic Review.

Lung

January 2025

Department of Medicine, National University Hospital, NUHS Tower Block, Level 10, 1E Kent Ridge Road, Singapore, 119228, Singapore.

Purpose: Tuberculosis (TB) is a highly contagious infection and one of the world's leading causes of death from a single infectious agent. Currently, TB diagnosis can be established via mycobacterial cultures, Acid Fast Bacilli smear and molecular studies. In the ever-evolving landscape of medical advancements, breath tests have shown considerable promise.

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Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer, with considerable variability in its clinical presentation and prognosis. Recent studies have focused on the relationship between its clinicopathological characteristics and inflammatory biomarkers, particularly the preoperative neutrophil-to-lymphocyte ratio (NLR). Our aim was to investigate the correlation between NLR and the clinicopathological features of PTC.

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Pediatric-type follicular lymphoma (PTFL) is an extremely rare B-cell lymphoma that primarily affects children and young adults, typically in individuals under 25 years old, with a median age of 15 years. Here, we report a rare case of PTFL in a 27-year-old adult male who presented with a slow-growing mass near his left ear. Initial CT scans of the neck revealed two oval-shaped, smooth, well-defined, homogeneously enhancing soft tissue density lesions in the superficial lobe of the left parotid gland.

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Background: Uncontrolled severe eosinophilic chronic rhinosinusitis (eCRS) is associated with elevated levels of Th2 cells and raised immunoglobulin concentrations in nasal polyp tissue. eCRS is characterized by high eosinophilic infiltration and type 2 inflammation. Gαi1/3 proteins participate in allergic inflammation by regulating immune cells.

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Arising of autoimmune gastritis after eradication in an elderly female patient.

Oxf Med Case Reports

January 2025

Department of Pathology, Okayama Saiseikai General Hospital, 1-17-18 Ifuku-Cho, Kita-Ku, Okayama-shi, Okayama 700-8551, Japan.

Autoimmune gastritis (AIG) is a chronic condition in which the body's immune system mistakenly attacks the stomach lining, specifically targeting parietal cells that produce stomach acid and intrinsic factors. After the infection was eradicated, AIG developed in an elderly woman with symptoms of the disease. 1.

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Analysis of pulmonary sequestration cases, based on the 11-year birth defects surveillance data of Changsha hospitals.

Sci Rep

January 2025

Office of the National Agency for Drug Clinical Trials, Changsha Hospital for Maternal, Child Health Care of Hunan Normal University, 416 Chengnan Dong Rd, Yuhua, Changsha, 410007, Hunan, China.

Pulmonary sequestration (PS) is a rare congenital malformation that is characterized by the absence of a connection between a portion of the lung tissue and the tracheobronchial tree, with blood supply from arteries throughout the body. Abnormal lung tissue cannot perform the normal gas exchange function. In the absence of timely diagnosis and early intervention, some cases may need labor induction, and some of the infants who survive may develop symptoms in childhood.

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Background: Children with end-stage heart failure listed for cardiac transplantation may require mechanical ventilation and/or circulatory support whilst awaiting transplantation. A subgroup of these patients is unable to wean off mechanical ventilator support and undergo tracheostomy to enhance quality of life and allow de-escalation of intensive care. There is limited evidence of the use of tracheostomy associated with pediatric cardiac transplantation.

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The objective of this study was to evaluate the flavor profiles of water-boiled pork meatballs at different ultrasonic powers (0, 150, 300, 450, 600, and 750 W) using solid-phase microextraction gas chromatography-mass spectrometry (SPME-GC-MS) combined with electronic nose (E-nose). A total of 36 volatile compounds were determined by SPME-GC-MS, including alcohols, aromatic hydrocarbons, aldehydes, terpenes, alkanes, phenols, ketones, and other. With the appropriate ultrasound treatment, the type and relative content of volatile compounds were significantly increased (P < 0.

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Pyrimidinergic P2Y1-Like Nucleotide Receptors Are Functional in Rat Conjunctival Goblet Cells.

Invest Ophthalmol Vis Sci

January 2025

Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States.

Purpose: To investigate the presence of uridine-5'-triphosphate (UTP)-activated P2Y1-like nucleotide receptors (P2Y2R, P2Y4R, and P2Y6R) in conjunctival goblet cells (CGCs) and determine if they increase intracellular Ca2+ concentration ([Ca2+]i) and induce mucin secretion.

Methods: Adult, male rat conjunctiva was used for culture of CGCs. To investigate the expression of P2YRs, mRNA was extracted from CGCs and used for reverse transcription PCR (RT-PCR) with commercially obtained primers specific to P2Y2R, P2Y4R, and P2Y6R.

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Improved Annotation of Asthma Gene Variants with Cell Type Deconvolution of Nasal and Lung Expression-Quantitative Trait Loci.

Am J Respir Cell Mol Biol

January 2025

University of Groningen, University Medical Center Groningen, Department of Pulmonology and Pediatric Allergy, Beatrix Children's Hospital, Groningen, Netherlands.

Asthma is a genetically complex inflammatory airway disease associated with over 200 Single nucleotide polymorphisms (SNPs). However, the functional effects of many asthma-associated SNPs in lung and airway epithelial samples are unknown. Here, we aimed to conduct expression quantitative trait loci (eQTL) analysis using a meta-analysis of nasal and lung samples.

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Sap Anthropometric Landmark: A Morphometric Orientation Point of the Nasal Tip.

J Craniofac Surg

January 2025

Department of Oral and Maxillofacial Surgery, Azerbaijan Medical University, Baku, Azerbaijan.

The aim of the present study is to introduce a new anthropometric landmark (sap), parameter (sap-sap) for measuring a width of nasal tip and 7 new proportion indexes. For determinate data mean with standard deviation, 200 healthy individuals (100 men and 100 women) were included in the study. The authors determined and pointed 9 paired cranio-facial anthropometric landmarks: sap, al, ac, mf, en, ex, zy, ch, go.

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Viral infections are characterized by dispersal from an initial site to secondary locations within the host. How the resultant spatial heterogeneity shapes within-host genetic diversity and viral evolutionary pathways is poorly understood. Here, we show that virus dispersal within and between the nasal cavity and trachea maintains diversity and is therefore conducive to adaptive evolution, whereas dispersal to the lungs gives rise to population heterogeneity.

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Background: Age-related hearing loss and mild cognitive impairment (MCI) independently increase dementia risk. The Ageing and Cognitive Health Evaluation in Elders randomised controlled trial (RCT) found hearing aids reduce cognitive decline in high-risk older adults with poor hearing.

Methods: This pilot RCT in London memory clinics randomised people with MCI (aged ≥55, untreated hearing loss defined as Pure Tone Average 0.

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Design Principles From Natural Olfaction for Electronic Noses.

Adv Sci (Weinh)

January 2025

Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Boston, MA, 02134, USA.

Natural olfactory systems possess remarkable sensitivity and precision beyond what is currently achievable by engineered gas sensors. Unlike their artificial counterparts, noses are capable of distinguishing scents associated with mixtures of volatile molecules in complex, typically fluctuating environments and can adapt to changes. This perspective examines the multifaceted biological principles that provide olfactory systems their discriminatory prowess, and how these ideas can be ported to the design of electronic noses for substantial improvements in performance across metrics such as sensitivity and ability to speciate chemical mixtures.

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This report describes a rare case of a paraganglioma occurring beneath the vocal folds. During the preoperative biopsy, we encountered significant hemorrhage, forcing us to stop the procedure and preventing us from obtaining a definitive diagnosis. Despite these challenges, the eventual surgery had a good outcome.

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Odourant receptors (ORs) are not restricted only to the nose, but also occur in many other organs and tissues, including the reproductive system. In fact, ORs are the most heavily expressed in testis than in any other extra-nasal tissue. Accumulating evidence suggests that olfactory and reproductive systems are both structurally and functionally linked and that these interconnections can influence various aspects of reproduction.

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Aim: This study aimed to evaluate the prevalence, location and diameters of Posterior superior alveolar artery (PSAA) and Infraorbital foramen (IOF) to find out whether there is any relationship between PSAA and IOF, and to predict their location relative to each other in surgical procedures by using cone beam computed tomography (CBCT).

Material And Method: Bilateral maxillary sinuses were analysed retrospectively in 170 patients with no missing teeth in the maxillary posterior region. The largest locations of PSAA and IOF in the maxillary sinus were determined and their size, shape, location in relation to the teeth and distances from anatomical points were evaluated.

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Semiconductor metal oxide (SMO) gas sensors are gaining prominence owing to their high sensitivity, rapid response, and cost-effectiveness. These sensors detect changes in resistance resulting from oxidation-reduction reactions with target gases, responding to a variety of gases simultaneously. However, their inherent limitations lie in selectivity.

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The use of air-jet dry powder inhalers (DPIs) offers a number of advantages for the administration of pharmaceutical aerosols, including the ability to achieve highly efficient and potentially targeted aerosol delivery to the lungs of children using the oral or trans-nasal routes of administration. To better plan targeted lung delivery of pharmaceutical aerosols with these inhalers, more information is needed on the extrathoracic (ET) depositional loss in pediatric subjects when using relatively small (e.g.

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Objective: The aim of this study was to assess hearing level of preschoolers with delayed speech in order to detect any underlying hearing loss Methods: In this research we targeted preschool children with speech delay, who have not been previously diagnosed with any medical or psychological illnesses. A total of 54 preschool speech-delayed children were audiologically assessed in our clinic in the past year. The age at time of referral ranged from two to 7.

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Exploring diverse biomaterials and implants in the ear, nose, and throat by understanding adverse effects and post-usage events. Literature was obtained from Scopus, PubMed, Google Scholar, and Web of Science. A comprehensive analysis was conducted on original research studies, case reports, and case series spanning from December 2010 to May 2022.

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Background: Chewing involves jaw movements that propel cerumen along the ear canal. This mechanism may be reduced in dysphagia, especially for older individuals who are enterally fed. Those patients may be at a higher risk for cerumen impaction and may require longer hospital stays.

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Auricular Mucormycosis: Comprehensive Literature Review.

Ear Nose Throat J

January 2025

Department of Otorhinolaryngology, Al Mouwasat University Hospital, Damascus University, Damascus, Syria.

Auricular mucormycosis is an exceptionally rare and aggressive fungal infection primarily affecting immunocompromised individuals, particularly those with poorly controlled diabetes. This report presents the case of a 54-year-old diabetic woman with isolated auricular mucormycosis and facial nerve palsy. The patient developed right auricular edema, necrosis, and severe pain, progressing over 10 days, with no history of trauma.

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