11 results match your criteria: "Norwegian University for Life Sciences[Affiliation]"

Article Synopsis
  • Oxygen supply is a challenge in aerobic high cell density culturing of bacteria, but denitrification with nitrogen oxides offers a promising alternative due to higher solubility of NO in water and harmless end products.
  • The novel pH-stat approach using HNO helps regulate pH and sustain NO concentration during the process, allowing for successful high-density growth of the model strain Paracoccus denitrificans using glucose and NO.
  • Despite achieving a dry weight of 20 g/L, slower growth rates were observed, attributed to CO/HCO buildup that suppressed pH and affected NO feeding, while unbalanced electron flow could lead to toxic intermediate concentrations.
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Background: Communication is a central tool in managing the balance between outdoor recreation and environmental protection. Several studies have evaluated different communication measures in nature area case studies, but rarely are these measures compared across contexts. We systematically map the literature guided by the question, what is the evidence base of on-site communication in outdoor recreation to change human behavior towards a more sustainable direction? Taking vulnerable natural areas as our starting point, we map distribution and abundance of communication measures, study design and outcome-related themes.

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Road runoff carries a mixture of contaminants that threatens the quality of natural water bodies and the health of aquatic organisms. The use of sedimentation ponds is a nature-based solution for the treatment of road runoff. This study assessed the concentration of polycyclic aromatic hydrocarbons (PAHs) and their alkylated homologues in sediment from seven highway sedimentation ponds and three natural urban ponds.

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Reply: Impact of first-line cancer treatment on follicle quality in cryopreserved ovarian samples.

Hum Reprod

May 2020

Department of Women's and Children's Health, NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, 171 64 Solna, Sweden.

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Impact of first-line cancer treatment on the follicle quality in cryopreserved ovarian samples from girls and young women.

Hum Reprod

September 2019

Department of Women's and Children's Health, NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Solna, Sweden.

Study Question: Does first-line chemotherapy affect the quality of ovarian pre-antral follicles and stromal tissue in a population of young patients?

Summary Answer: Exposure to first-line chemotherapy significantly impacts follicle viability, size of residual intact follicles, steroid secretion in culture and quality of the stromal compartment.

What Is Known Already: First-line chemotherapy is considered to have a low gonadotoxic potential, and as such, does not represent an indication for fertility preservation. Studies investigating the effects of chemotherapy on the quality of ovarian tissue stored for fertility preservation in young patients are limited and the results sometimes contradictory.

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Confusion about the species richness of human gut microbiota.

Benef Microbes

August 2016

1 Department of Chemistry, Biotechnology and Food Science, Norwegian University for Life Sciences, 1430 Ås, Norway.

A key message from a range of high profile next generation sequencing studies on the human microbiota is that it composes a tremendously rich community of more than 1000 species within each one of us. Although more recent studies have shown estimates of between 100 and 200 species per individual, this has not yet been made clear in the literature. Currently, the most widely accepted estimate of species richness is therefore five to ten times too high.

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Dominant short repeated sequences in bacterial genomes.

Genomics

March 2015

Department of Chemistry, Biotechnology and Food Science, Norwegian University for Life Sciences, Ås, Norway; Hedmark University College, Hamar, Norway. Electronic address:

We use a novel multidimensional searching approach to present the first exhaustive search for all possible repeated sequences in 166 genomes selected to cover the bacterial domain. We found an overrepresentation of repeated sequences in all but one of the genomes. The most prevalent repeats by far were related to interspaced short palindromic repeats (CRISPRs)—conferring bacterial adaptive immunity.

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Gene expression of TLR homologues identified by genome-wide screening of the earthworm Dendrobaena veneta.

Innate Immun

February 2015

Faculty of Education and Science, Hedmark University College, Hamar, Norway Department of Chemistry, Biotechnology and Food Science, Norwegian University for Life Sciences, Ås, Norway

TLRs represent one of the most important components of innate immunity. Currently, these receptors have been extensively studied in vertebrates and insects, but our knowledge for annelids is very limited. Therefore, the aim of our study was to identify earthworm TLR homologs by genome-wide screening, and to determine the expression of candidate genes as a response to Gram-positive and Gram-negative bacteria.

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Dominant fecal microbiota in newly diagnosed untreated inflammatory bowel disease patients.

Gastroenterol Res Pract

December 2013

Hedmark University College, 2306 Hamar, Norway ; Department of Chemistry, Biotechnology and Food Science, Norwegian University for Life Sciences, 1432 Ås, Norway.

Our knowledge about the microbiota associated with the onset of IBD is limited. The aim of our study was to investigate the correlation between IBD and the fecal microbiota for early diagnosed untreated patients. The fecal samples used were a part of the Inflammatory Bowel South-Eastern Norway II (IBSEN II) study and were collected from CD patients (n = 30), UC patients (n = 33), unclassified IBD (IBDU) patients (n = 3), and from a control group (n = 34).

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Age-dependent fecal bacterial correlation to inflammatory bowel disease for newly diagnosed untreated children.

Gastroenterol Res Pract

May 2013

Hedmark University College, Hamar, Norway ; Department of Chemistry, Biotechnology and Food Science, Norwegian University for Life Sciences, Ås, Oslo, Norway.

The knowledge about correlation patterns between the fecal microbiota and inflammatory bowel diseases (IBD)-comprising the two subforms Crohn's disease (CD) and ulcerative colitis (UC)-for newly diagnosed untreated children is limited. To address this knowledge gap, a selection of faecal specimens (CD, n = 27 and UC, n = 16) and non-IBD controls (n = 30) children (age < 18 years) was analysed utilising bacterial small subunit (SSU) rRNA. We found, surprising age dependence for the fecal microbiota correlating to IBD.

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High or low correlation between co-occuring gene clusters and 16S rRNA gene phylogeny.

FEMS Microbiol Lett

February 2013

Department of Chemistry, Biotechnology and Food Science, Norwegian University for Life Sciences, Ås, Norway.

Ribosomal RNA (rRNA) genes are universal for all living organisms. Yet, the correspondence between genome composition and rRNA phylogeny remains poorly known. The aim of this study was to use the information from genome sequence databases to address the correlation between rRNA gene phylogeny and total gene composition in bacteria.

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