3 results match your criteria: "Norway. daniel.bastian@rikshospitalet.no[Affiliation]"
LBP and sCD14 patterns in total hip replacement surgery performed during combined spinal/epidural anaesthesia.
Scand J Clin Lab Invest
October 2011
Department of Orthopaedics, Oslo University Hospital/Rikshospitalet, Oslo, Norway.
Article Synopsis
- The study investigates the immune response influenced by lipopolysaccharide-binding protein (LBP) and soluble CD14 (sCD14) in patients undergoing total hip replacement surgery.
- Blood samples were collected before and after surgery to measure levels of LBP and sCD14, along with inflammatory cytokines.
- The results showed increased levels of LBP at 24 hours and peaking at 3 days post-surgery, indicating a primed immune response due to the surgical trauma.
Local and systemic chemokine patterns in a human musculoskeletal trauma model.
Inflamm Res
August 2009
Department of Orthopaedics, Oslo University Clinic, Rikshospital, Sognsvannsveien 20, 0027 Oslo, Norway.
Objective And Design: This prospective study aims to identify differences in local and systemic chemokines kinetics within 24 h of a standardised human surgical trauma (total hip arthroplasty) and their impact on systemic polymorphonuclear cells.
Materials And Methods: We examined seven patients with coxarthrosis, but without comorbidity, who had a total hip arthroplasty. Local drained blood and systemic blood samples were collected at wound closure and at 1, 4, and 24 h after surgery.
Systemic and local cytokine kinetics after total hip replacement surgery.
Eur Surg Res
January 2009
Department of Orthopaedics, Rikshospitalet University Clinic, University of Oslo, Oslo, Norway.
Background: Trauma induces local and subsequent systemic inflammatory reactions. Aberrant reactions can lead to a systemic inflammatory response syndrome, with a potentially lethal outcome. Our aim was to investigate the early local cytokine kinetic compared to systemic changes in a standardized surgical trauma.
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