207,424 results match your criteria: "Norway; Chr. Michelsen Institute[Affiliation]"

Antidepressants exhibit a considerable variation in efficacy, and increasing evidence suggests that individual genetics contribute to antidepressant treatment response. Here, we combined data on antidepressant non-response measured using rating scales for depressive symptoms, questionnaires of treatment effect, and data from electronic health records, to increase statistical power to detect genomic loci associated with non-response to antidepressants in a total sample of 135,471 individuals prescribed antidepressants (25,255 non-responders and 110,216 responders). We performed genome-wide association meta-analyses, genetic correlation analyses, leave-one-out polygenic prediction, and bioinformatics analyses for genetically informed drug prioritization.

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Microbial research generates vast and complex data from diverse omics technologies, necessitating innovative analytical solutions. microGalaxy (Galaxy for Microbiology) addresses these needs with a user-friendly platform that integrates >220 tool suites and >65 curated workflows for microbial analyses, including taxonomic profiling, assembly, annotation, and functional analysis. Hosted on the main EU Galaxy server (microgalaxy.

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Utilizing the soft-lattice nature of metal halide perovskites, we employ post-synthetic cross-ion exchange to synthesize a series of narrow band-gap colloidal nanocrystals of methylammonium-based lead iodide solid solutions of composition FAMAPbI, as well as those of triple-cation composition CsFAMAPbI (TCPbI). The ability to finely tune the compositions not only helps in tailoring the optical properties in the near-infrared region, but also improves the stability of these colloidal nanocrystals towards moisture, which has been demonstrated as compared to their bulk counterparts. The thermal stability of these solid solutions is also comparable to that of the bulk, as evidenced by thermogravimetric studies.

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Objective: Salmon fish farming has become a major industry in Norway, increasingly dependent on contracted maritime transport and different special services. The aim of the paper was to explore work safety for contractors in Norwegian fish farming. Previous research from other industries illustrates contractors are more susceptible to time and work pressure, have more hazardous jobs, and are more accident-prone, compared to fixed employees.

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Background: During lactation, maternal requirements for many nutrients increase due to the physiological demands of breast milk production, reflected in dietary recommendations. BMI is negatively associated with dietary quality postpartum, and 40% of women in Norway have pre-pregnancy overweight and obesity. Currently, there is limited data on dietary intake among lactating women in Norway and whether they meet nutritional requirements.

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We summarise key messages from the World Bank Report . A central lesson of the Report is that in decision-making on the path to Universal Health Coverage (UHC), procedural fairness matters alongside substantive fairness. Decision systems should be assessed using a complete conception of procedural fairness that embodies core commitments to impartial and equal consideration of interests and perspectives.

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Hope among patients discharged from an intensive care unit: A prospective cohort study.

Nurs Crit Care

January 2025

Department of Postoperative and Intensive Care Nursing, Division of Emergencies and Critical Care, Oslo University Hospital, Oslo, Norway.

Background: Hope is important during critical illness due to the uncertainty and loss of control in the patient's life. Following intensive care, hope might provide a therapeutic effect and increase coping, leading to improved recovery.

Aim: To describe the levels of hope in patients during the first year after ICU treatment, and to explore possible associations between hope and selected demographic, clinical and psychosocial factors.

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Companion animal and equine clinical research: a Nordic perspective.

Acta Vet Scand

January 2025

Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Sciences, PO Box 7054, 750 07, Uppsala, Sweden.

Background: The societal value of cats, dogs and horses is high, and the companion and sport animal health care sector is growing. Clinical research concerning cats, dogs and horses is crucial for the development of evidence-based medical care that benefits animals and their owners, and has implications for human and environmental health from a One Health perspective. Basic information on companion animal and equine research enables more directed measures to improve conditions for research within the area.

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The characterization of tunnel wash water (TWW) from 12 Norwegian tunnels showed very high concentrations of total suspended solids (TSS), metals, and polycyclic aromatic hydrocarbons (PAHs). Iron (Fe), aluminum (Al), and manganese (Mn) were mainly particle-associated. They are efficiently removed by sedimentation, while the dissolved concentrations of toxic metals like Cu, Zn, and As did not change.

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Pseudomonas aeruginosa is an emergent threat due to the antimicrobial resistance crisis. Bacteriophages (phages) are promising agents for phage therapy approaches against P. aeruginosa.

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It is well known that elite athletes of specific ethnicities and/or nationalities dominate certain sports disciplines (e.g., East Africans in marathon running).

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Arctic permafrost is undergoing rapid changes due to climate warming in high latitudes. Retrogressive thaw slumps (RTS) are one of the most abrupt and impactful thermal-denudation events that change Arctic landscapes and accelerate carbon feedbacks. Their spatial distribution remains poorly characterised due to time-intensive conventional mapping methods.

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Objectives: The objective of this study was to assess the quality of ECG recordings and the concordance between the automatic detection of cardiac arrhythmia episodes by a patch ECG and an insertable cardiac monitor.

Design: Prospective cohort study.

Setting And Participants: Endurance athletes diagnosed with paroxysmal atrial fibrillation (AF) and no other relevant comorbidities participating in a randomised controlled trial on the effects of training adaption.

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FAP expression is scarce in epithelial cells.

Gastroenterology

January 2025

Université Paris Cité, Centre de Recherche sur l'Inflammation (CRI), INSERM, U1149, CNRS, ERL 8252, F-75018 Paris, France; Department of Pathology, APHP Nord, FHU MOSAIC, Beaujon Hospital, Clichy, France. Electronic address:

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A functional bioink with potential in bone tissue engineering must be subjected to critical investigation throughout its intended lifespan. The aim of this study was to develop alginate-gelatin-based (Alg-Gel) multicomponent bioinks systematically and to assess the short- and long-term exposure responses of human bone marrow stromal cells (hBMSCs) printed within these bioinks with and without crosslinking. The first generation of bioinks was established by incorporating a range of cellulose nanofibrils (CNFs), to evaluate their effect on viscosity, printability and cell viability.

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Objectives: Randomized clinical trials informing clinical practice (e.g., like large, pragmatic, and late-phase trials) should ideally mostly use harmonized outcomes that are important to patients, family members, clinicians, and researchers.

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Proteomics- and metabolomics-based analysis of the regulation of germination in Norway maple and sycamore embryonic axes.

Tree Physiol

January 2025

Laboratoire de Biologie du Développement, UMR 7622, Institut de Biologie Paris-Seine (IBPS), Sorbonne Université, CNRS, F-75005 Paris, France.

Norway maple and sycamore belong to the Acer genus and produce desiccation-tolerant and desiccation-sensitive seeds, respectively. We investigated the seed germination process at the imbibed and germinated stages using metabolomic and proteomic approaches to determine why sycamore seeds germinate earlier and are more successful at establishing seedlings than Norway maple seeds under controlled conditions. Embryonic axes and embryonic axes with protruded radicles were analyzed at the imbibed and germinated stages, respectively.

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This study aimed to test the use of Rietveld refinement on respirable aerosol samples to determine the phase of respirable crystalline silica (RCS) and other minerals. The results from the Rietveld refinement were compared to an external standard method and gravimetrical measurements. Laboratory samples consisting of α-quartz, feldspar, and calcite with variable proportions and total mass loadings were made and analyzed using the NIOSH 7500 , followed by Rietveld refinement.

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The L-asparaginase is commercial enzyme used as chemotherapeutic agent in cancer treatment and food processing agent in backed and fried food industries. In the present research work, the artificial intelligence and machine learning techniques were employed for modeling and optimization of fermentation process conditions for enhanced production of L-asparaginase by submerged fermentation of . The experimental L-asparaginase activity obtained using central composite experiment design was used for optimization.

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Biological material and health information from patients are valuable for medical research. Under a "broad" consent model, hospital patients in Norway can consent to their biological material and health information being stored in research biobanks and used for "specific, broadly defined research purposes" within a specified medical research area but not for medical research in general. Patients are asked to provide new consent each time researchers wish to use their material in a different medical research area.

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Article Synopsis
  • The study focused on oral health prevention, particularly root caries measures, for patients aged 65 and older, and involved a survey of 365 Norwegian dental hygienists from both public and private sectors.
  • Key findings revealed that primary prevention methods included oral hygiene instruction and fluoride varnish, while challenges such as patients' reduced manual dexterity and mobility were particularly noted by public dental hygienists.
  • The research highlights the vital role of dental hygienists in promoting oral health for the elderly and underscores various challenges they face in implementing preventive care.
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