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GMBP1-conjugated manganese oxide nanoplates for monitoring of gastric cancer MDR using magnetic resonance imaging.
RSC Adv
April 2020
School of Information Sciences and Technology, Northwest University Xi'an 710127 Shaanxi China
Multidrug resistance (MDR) is a huge challenge for gastric cancer chemotherapy. Therefore, MDR accurate monitoring is of great significance for the treatment of gastric cancer. GMBP1, an extracellular internalization peptide, can target MDR gastric cancer cells through specific binding to GRP78, which is an MDR-related protein that is overexpressed in gastric cancer cells.
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