Predictive value of initial Lp-PLA2, NT-proBNP, and peripheral blood-related ratios for heart failure after early onset infarction in patients with acute myocardial infarction.

Objective: To analyze the predictive value of lipoprotein-associated phospholipase A2 (Lp-PLA2), N-terminal prohormone of brain natriuretic peptide (NT-proBNP), and peripheral blood-related ratios at the initial diagnosis for heart failure (HF) after early-onset infarction in patients with acute myocardial infarction (AMI).

Methods: This retrospective analysis included 151 patients first diagnosed with AMI at Xianyang Central Hospital from February 2020 to February 2023. Patients were classified into two groups: those who developed HF during hospitalization (HF group, n=45) and those who did not (non-HF group, NHF, n=106).

Prognostic value and risk model construction of hypoxic stress-related features in predicting gastric cancer.

Objective: Hypoxia promotes tumor progression from multiple aspects, including metabolism, proliferation, migration and angiogenesis. Therefore, a thorough understanding of the impact of hypoxia on gastric adenocarcinoma (STAD) is warranted. The aim of the present study was to find a prognostic model of hypoxia in gastric cancer (GC) and its relationship with the immune microenvironment.