The biological function of and its application in animal husbandry: a review.

, is a herbaceous plant of the Asteraceae family which is a traditional Chinese herbal medicine. It is often used for dehumidification, antiemetics, spleen strengthening and antipyretic effects. is rich in various bio-active substances and has many biological functions, for instance anti-inflammatory, antioxidant and antiviral effects.

Effects of residual black fruit on growth performance, rumen fermentation parameters, microflora and economic benefits of fattening sheep.

Introduction: The residual black wolfberry fruit (RBWF) is rich in nutrients and contains a diverse range of active substances, which may offer a viable alternative to antibiotics. This experiment was conducted to investigate the impact of varying levels of RBWF on the growth performance and rumen microorganisms of fattening sheep, and to quantify its economic benefits.

Methods: In this experiment, 40 three-month-old and male Duolang sheep with an average weight of 29.

Coverage and associated factors of vitamin-A supplementation among children aged 6-59 months in Gondar City, Northwest Ethiopia, 2022: a community-based cross-sectional study.

Introduction: vitamin A is a nutrient required for normal visual system function, growth, and development. Periodic vitamin A supplementation is a cost-effective strategy for preventing vitamin A deficiency in children. This study aimed to assess the coverage and associated factors of vitamin A supplementation among children aged 6-59 months in Gondar City, Northwest Ethiopia 2022.

Pain Perception Threshold in Young High-Altitude Natives After Acute Exposure to Severe Hypoxic Conditions.

Previous studies indicate that individuals at high altitudes have a lower pain threshold than those living at sea level. This study evaluates the differences in pain perception among young people living at an altitude of 3800 m and after acute exposure to a severe hypoxic environment at more than 5100 m. Fourteen people (BMI of 22.

Natural variation in MdNAC5 contributes to fruit firmness and ripening divergence in apple.

Fruit firmness is an important trait for characterizing the quality and value of apple. It also serves as an indicator of fruit maturity, as it is a complex trait regulated by multiple genes. Resequencing techniques can be employed to elucidate variations in such complex fruit traits.

Ongoing post-pandemic peak of cases in July 2024: A single-center experience in north-west Italy.

We report an increase of () respiratory infections during 2023-2024. The positive rate in 2024 is higher at 68 per 1668 (5%) compared with 2023 at nine per 1264 (0.7%), highlighting the increased circulation in north-west Italy.

Evidence of a 4.33 billion year age for the Moon's South Pole-Aitken basin.

The Moon's farside South Pole-Aitken (SPA) basin is the largest and oldest visible impact basin in the inner Solar System. Determining the timing of this catastrophic event is key to understanding the onset of the lunar basin-forming epoch, with implications for understanding the impact bombardment history of the inner Solar System. Despite this, the formation age of the SPA basin remains poorly constrained.

Pharmacist-led DE-eSCALation of opioids post-surgical dischargE (DESCALE) - A multi-centre, non-randomised, feasibility study protocol.

Background: Opioids are frequently prescribed for short-term acute pain following surgery. Used appropriately, opioids deliver extremely favourable pain relief. Used longer than 90-days, however, can result in health complications, including unintentional overdose and addiction.

The Role of Aryl Hydrocarbon Receptor in Skin Homeostasis: Implications for Therapeutic Strategies in Skin Disorders.

The aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, is extensively expressed in diverse human organs and plays a pivotal role in mediating the onset, progression, and severity of numerous diseases. Recent research has explored the substantial impact of AhR on skin homeostasis and related pathologies. As a multi-layered organ, the skin comprises multiple cell populations that express AhR.

Analysis of Risk Factors for Gastric Cancer and Precancerous Lesions: A Case-Control Study.

Objectives: To investigate the correlation between gastric xanthoma (GX) and precancerous lesions (PCL) and gastric cancer (GC), and to explore other potential risk factors for PCL and GC in northwest China.

Methods: A case-control study was conducted from September 2022 to September 2023 at Xijing Hospital, Air Force Medical University (Xi'an, Shaanxi Province, China). The patients who underwent gastroscopy were enrolled and divided into the chronic gastritis (CG) group (n = 423), PCL group (n = 422), and GC group (n = 415).

Anemia and its predictors among patients on hemodialysis, at Felege Hiote Referral Hospital, Northwest Ethiopia, 2022: a retrospective cohort study.

Background: Anemia is a critical complication among hemodialysis patients, often leading to poor outcomes. This study aimed to assess anemia prevalence and identify predictors among hemodialysis patients at Felege Hiote Referral Hospital, Northwest Ethiopia, in 2022.

Research Design And Methods: A retrospective cohort study analyzed 410 hemodialysis patients from January 2018 to February 2022.

U in a Conserved Pseudotetrahedral Imidophosphorane Coordination Sphere.

While several ligand systems support uranium across a range of oxidation states, spanning more than two oxidation states in a conserved coordination geometry is uncommon among structurally authenticated complexes. Imidophosphorane ligands significantly stabilize high-valent lanthanide and actinide complexes. Here, we report a series of homoleptic uranium imidophosphorane complexes, spanning the +4, +5 and +6 oxidation states in a four-coordinate pseudotetrahedral ligand field.

Clin-STAR Corner: Rehabilitation for Older Adults With Heart Failure.

Heart failure is a major contributor to morbidity, mortality, and healthcare costs, especially among older adults. Despite a large body of evidence supporting the benefits of cardiac rehabilitation, less than 30% of eligible Medicare beneficiaries participate in cardiac rehabilitation. Thus, it is essential to examine alternatives, such as physical rehabilitation, a rehabilitation approach that focuses on physical activity and function.

Determination of Pathogens in Surgical Site Infections in Ankle Fractures and Implications for Empirical Antibiotic Treatment.

Surgical site infections (SSIs) are the most common complication after surgery for ankle fractures. This retrospective study aimed to determine the pathogens cultured in SSI and their antimicrobial susceptibility patterns to provide a recommendation for empirical therapy. Patients who underwent surgical treatment for an ankle fracture were included.

CaML: Chemistry-informed machine learning explains mutual changes between protein conformations and calcium ions in calcium-binding proteins using structural and topological features.

Proteins' flexibility is a feature in communicating changes in cell signaling instigated by binding with secondary messengers, such as calcium ions, associated with the coordination of muscle contraction, neurotransmitter release, and gene expression. When binding with the disordered parts of a protein, calcium ions must balance their charge states with the shape of calcium-binding proteins and their versatile pool of partners depending on the circumstances they transmit. Accurately determining the ionic charges of those ions is essential for understanding their role in such processes.

Organic manure and fertilizer N management strategies improve soil health at different growth stages of pearl millet under pearl millet-wheat sequence.

Background: Incorporating organic manure improves soil properties and crop productivity. A long-term study started in October 1967 examined the effects of farmyard manure and nitrogen fertilization on the soil at key growth stages of pearl millet in a pearl millet-wheat cropping system over its 51st cycle.

Results: Applying 15 Mg of farmyard manure (FYM) per hectare in both growing seasons significantly boosted soil organic carbon (SOC), dissolved organic carbon (DOC), and key nutrients compared to one-season application.

Petrophysical assessment of the Hammam Faraun, Matulla and Nubia Reservoirs in the Ashrafi Oil Field, Gulf of Suez.

The Hammam Faraun, Matulla, and Nubia formations in the Ashrafi oil field, in the southern Gulf of Suez, Egypt, are key hydrocarbon reservoirs with significant economic importance. These formations, characterized by their favorable reservoir properties and structural settings, play a crucial role in oil and gas accumulation. Their study provides valuable insights into regional petroleum systems and guides exploration and production activities.

Impacts of irrigation expansion on moist-heat stress based on IRRMIP results.

Irrigation rapidly expanded during the 20 century, affecting climate via water, energy, and biogeochemical changes. Previous assessments of these effects predominantly relied on a single Earth System Model, and therefore suffered from structural model uncertainties. Here we quantify the impacts of historical irrigation expansion on climate by analysing simulation results from six Earth system models participating in the Irrigation Model Intercomparison Project (IRRMIP).

Posttranslational modifications in cardiac metabolic remodeling mediated by metabolites: Implications for disease pathology and therapeutic potential.

The nonenergy-producing or biomass-accumulating functions of metabolism are attracting increasing attention, as metabolic changes are gaining importance as discrete signaling pathways in modulating enzyme activity and gene expression. Substantial evidence suggests that myocardial metabolic remodeling occurring during diabetic cardiomyopathy, heart failure, and cardiac pathological stress (e.g.

Antioxidant and hepatic fibrosis-alleviating effects of selenium-modified Bletilla striata polysaccharide.

Liver fibrosis is a significant precursor to cirrhosis and liver cancer, yet effective treatments remain elusive. Our previous studies demonstrated that Bletilla striata polysaccharide (BSP) has therapeutic effects, though it performed poorly at medium concentrations. To address this limitation, BSP underwent selenization modification.

Inhibitory activity and mechanisms of chitosan against Fusarium avenaceum, a pathogen causing Angelica root rot disease.

The polysaccharide chitosan possesses broad-spectrum antimicrobial properties and has proven effective in controlling various postharvest diseases in fruits. Nevertheless, the fundamental mechanisms underlying its action remain unclear. In this study, the antifungal effects of chitosan with different molecular weights against Fusarium avenaceum, a pathogen causing root rot in Angelica sinensis, were evaluated.

Decoding Cortical Folding Patterns in Marmosets Using Machine Learning and Large Language Model.

Macroscale neuroimaging results have revealed significant differences in the structural and functional connectivity patterns of gyri and sulci in the primate cerebral cortex. Despite these findings, understanding these differences at the molecular level has remained challenging. This study leverages a comprehensive dataset of whole-brain in situ hybridization (ISH) data from marmosets, with updates continuing through 2024, to systematically analyze cortical folding patterns.

Whole-transcriptome analysis reveals the profiles and roles of coding and non-coding RNAs during hair follicle cycling in Rex rabbits.

Background: Rex rabbit is famous for its silky and soft fur coat, a characteristic predominantly attributed to its hair follicles. Numerous studies have confirmed the crucial roles of mRNAs and non-coding RNAs (ncRNAs) in regulating key cellular processes such as cell proliferation, differentiation, apoptosis and immunity. However, their involvement in the regulation of the hair cycle in Rex rabbits remains unknown.

Removal of Antibiotics in Breeding Wastewater Tailwater Using Microalgae-Based Process.

Ciprofloxacin (CIP) and oxytetracycline (OTC) are commonly detected antibiotic species in breeding wastewater, and microalgae-based antibiotic treatment technology is an environmentally friendly and cost-effective method for its removal. This study evaluated the effects of CIP and OTC on Scenedesmus sp. in the breeding wastewater tailwater and the removal mechanisms of antibiotics.

Evaluation of Heavy Metal Contamination from Large-scale Swine-Farming Wastewater in Sichuan Province, China: Removal Efficiency, Spatial Distribution and Risk Assessment.

The widespread application of swine-farming wastewater to soil and water is increasingly contributing to heavy metal contamination, posing significant environmental risks. This study investigated the concentrations of eight heavy metals in swine-farming wastewater following different treatment processes, and assessed their ecological risks in Sichuan Province, China. The findings revealed that zinc, copper and nickel exhibited the highest concentrations, potentially causing heavy or strong contamination levels and leading to heavy or slight ecological risks.