Physical Activity Amid a Pandemic: How Socioeconomic and Demographic Factors Shaped Behaviors During COVID-19.

The COVID-19 pandemic led to significant shifts in societal norms and individual behaviors, including changes in physical activity levels. This study examines the relationship between socioeconomic and sociodemographic factors and changes in physical activity levels during the pandemic compared to pre-pandemic levels among adult Arkansans. Survey data were collected from 1,205 adult Arkansans in July and August 2020, capturing socioeconomic and sociodemographic characteristics and information on physical activity changes since the onset of the pandemic.

Suppressing the progression of bladder cancer using cyclovirobuxine D based on network pharmacology and bioinformatics approaches.

Limited treatment options are available for bladder cancer (BCa) resulting in extremely high mortality rates. Cyclovirobuxine D (CVB-D), a naturally alkaloid, reportedly exhibits notable antitumor activity against diverse tumor types. However, its impact on CVB-D on BCa and its precise molecular targets remain unexplored.

The MADS-RIPENING INHIBITOR-DIVARICATA1 module regulates carotenoid biosynthesis in nonclimacteric Capsicum fruits.

Carotenoids play indispensable roles in the ripening process of fleshy fruits. Capsanthin is a widely distributed and utilized natural red carotenoid. However, the regulatory genes involved in capsanthin biosynthesis remain insufficient.

Neuroprotective Indole Alkaloids from the Soil-Derived Fungus sp. XZ8.

A chemical investigation of the soil-derived fungus sp. XZ8 led to the isolation of five new indole alkaloids, trichindoles A-E (-), with diverse architectures, along with seven known analogues (-). Their structures were elucidated by extensive spectroscopic data analysis, and their absolute configurations were determined by single-crystal X-ray diffraction and modified Mosher's method.

Atomic Gap-State Engineering of MoS for Alkaline Water and Seawater Splitting.

Transition-metal dichalcogenides (TMDs), such as molybdenum disulfide (MoS), have emerged as a generation of nonprecious catalysts for the hydrogen evolution reaction (HER), largely due to their theoretical hydrogen adsorption energy close to that of platinum. However, efforts to activate the basal planes of TMDs have primarily centered around strategies such as introducing numerous atomic vacancies, creating vacancy-heteroatom complexes, or applying significant strain, especially for acidic media. These approaches, while potentially effective, present substantial challenges in practical large-scale deployment.

CTHNet: A CNN-Transformer Hybrid Network for Landslide Identification in Loess Plateau Regions Using High-Resolution Remote Sensing Images.

The Loess Plateau in northwest China features fragmented terrain and is prone to landslides. However, the complex environment of the Loess Plateau, combined with the inherent limitations of convolutional neural networks (CNNs), often results in false positives and missed detection for deep learning models based on CNNs when identifying landslides from high-resolution remote sensing images. To deal with this challenge, our research introduced a CNN-transformer hybrid network.

Delay/Disruption Tolerant Networking Performance Characterization in Cislunar Relay Communication Architecture.

Future 7G/8G networks are expected to integrate both terrestrial Internet and space-based networks. Space networks, including inter-planetary Internet such as cislunar and deep-space networks, will become an integral part of future 7G/8G networks. Vehicle-to-everything (V2X) communication networks will also be a significant component of 7G/8G networks.

Role of PI3 Kinases in Cell Signaling and Soleus Muscle Atrophy During Three Days of Unloading.

During skeletal muscle unloading, phosphoinositide 3-kinase (PI3K), and especially PI3K gamma (PI3Kγ), can be activated by changes in membrane potential. Activated IP3 can increase the ability of Ca to enter the nucleus through IP3 receptors. This may contribute to the activation of transcription factors that initiate muscle atrophy processes.

Mechanism of THBS1 Regulation of MDCK Cell Proliferation and Apoptosis Through TGF-β/Smad Signalling.

Madin-Darby Canine Kidney (MDCK) cells are a key cell line for influenza vaccine production, due to their high viral yield and low mutation resistance. In our laboratory, we established a tertiary cell bank (called M60) using a standard MDCK cell line imported from American Type Culture Collection (ATCC) in the USA. Due to their controversial tumourigenicity, we domesticated non-tumourigenic MDCK cells (named CL23) for influenza vaccine production via monoclonal screening in the early stage of this study, and the screened CL23 cells were characterised based on their low proliferative capacity, which had certain limitations in terms of expanding their production during cell resuscitation.

Time-Course Transcriptomics Analysis Reveals Molecular Mechanisms of Salt-Tolerant and Salt-Sensitive Cotton Cultivars in Response to Salt Stress.

Salt stress is an environmental factor that limits plant seed germination, growth, and survival. We performed a comparative RNA sequencing transcriptome analysis during germination of the seeds from two cultivars with contrasting salt tolerance responses. A transcriptomic comparison between salt-tolerant cotton cv Jin-mian 25 and salt-sensitive cotton cv Su-mian 3 revealed both similar and differential expression patterns between the two genotypes during salt stress.

Abscisic Acid, Microtubules and Phospholipase D-Solving a Cellular Bermuda Triangle.

Rice plants are important food crops that are sensitive to cold stress. Microtubules (MTs) are highly associated with plant response to cold stress. The exogenous application of abscisic acid (ABA) can transiently induce the cold stability of microtubules.

Traditional Chinese Medicine Monomer Bakuchiol Attenuates the Pathogenicity of via Targeting PqsR.

As the antibiotic resistance of pathogens becomes increasingly severe, it is becoming more feasible to use methods that suppress the virulence of pathogens rather than exerting selective pressure on their growth. , a dangerous opportunistic pathogen, infects hosts by producing multiple virulence factors, which are regulated by quorum-sensing (QS) systems, including the systems, systems, and systems. This study used the chromosome transcription fusion reporter model to screen the traditional Chinese medicine monomer library and found that bakuchiol can effectively inhibit the system and related virulence phenotypes of , including the production of virulence factors (pyocyanin, hydrogen cyanide, elastase, and lectin) and motility (swarming, swimming, and twitching motility) without affecting its growth.

Polystyrene Microplastics Induce Photosynthetic Impairment in sp. at Physiological and Transcriptomic Levels.

The rising concentration of microplastics (MPs) in aquatic environments poses increasing ecological risks, yet their impacts on biological communities remain largely unrevealed. This study investigated how aminopolystyrene microplastics (PS-NH) affect physiology and gene expression using the freshwater alga sp. as the test species.

The Identification and Characterization of the Gene Family in Oliv. Heteromorphic Leaves Provide a Theoretical Basis for the Functional Study of .

Oliv. typically has four kinds of heteromorphic leaves: linear (Li), lanceolate (La), ovate (Ov) and broad ovate (Bo). Heteromorphic leaves help adapt to extreme desert environments and further contribute to protection against land desertification in Northwest China.

Microstructure and Mechanical Properties of Rolled (TiC + Ti1400)/TC4 Composites.

One of the long-standing challenges in the field of titanium matrix composites is achieving the synergistic optimization of high strength and excellent ductility. When pursuing high strength characteristics in materials, it is often difficult to consider their ductility. Therefore, this study prepared a Ti1400 alloy and in situ synthesized TiC-reinforced (TiC + Ti1400)/TC4 composites using low-energy ball milling and spark plasma sintering technology, followed by hot rolling, to obtain titanium matrix composites with excellent mechanical properties.

Characterization of MADS-Box Gene Family in and Functional Study of in Regulating Floral Transition and Formation.

In flowering plants, MADS-box genes play regulatory roles in flower induction, floral initiation, and floral morphogenesis. (. ) is a traditional Chinese medicinal plant.

Predicting the Global Distribution of L. Under Climate Change Based on Optimized MaxEnt Modeling.

The genus of L. are Tertiary-relict desert sand-fixing plants, which are an important forage and agricultural product, as well as an important source of medicinal and woody vegetable oil. In order to provide a theoretical basis for better protection and utilization of species in the L.

Elevated CO Shifts Photosynthetic Constraint from Stomatal to Biochemical Limitations During Induction in and .

The relative impacts of biochemical and stomatal limitations on photosynthesis during photosynthetic induction have been well studied for diverse plants under ambient CO concentration (). However, a knowledge gap remains regarding how the various photosynthetic components limit duction efficiency under elevated CO. In this study, we experimentally investigated the influence of elevated CO (from 400 to 800 μmol mol) on photosynthetic induction dynamics and its associated limitation components in two broadleaved tree species, and .

Characterizing Droughts During the Rice Growth Period in Northeast China Based on Daily SPEI Under Climate Change.

In agricultural production, droughts occurring during the crucial growth periods of crops hinder crop development, while the daily-scale standardized precipitation evapotranspiration index () can be applied to accurately identify the drought characteristics. In this study, we used the statistical downscaling method to obtain the daily precipitation (), maximum air temperature () and minimum air temperature () during the rice growing season in Heilongjiang Province from 2015 to 2100 under the SSP1-2.6, SSP2-4.

Anisotropic Microparticles with a Controllable Structure via Soap-Free Seeded Emulsion Polymerization.

Anisotropic particles have a wide range of applications in materials science such as emulsion stabilization, oil-water separation, and catalysis due to their asymmetric structure and properties. Nevertheless, designing and synthesizing large quantities of anisotropic particles with controlled morphologies continue to present considerable challenges. In this study, we successfully synthesized anisotropic microspheres using a soap-free seed emulsion polymerization method.

Comparative Analysis of miRNA Expression Profiles of Yak Milk-Derived Exosomes at Different Altitudes.

Yaks are a rare and unique animal species inhabiting the Qinghai-Tibet Plateau; they are renowned for their remarkable ability to thrive in harsh environments. Milk-derived exosomes, tiny vesicles containing various biological molecules, play crucial roles in numerous pathological and physiological processes, including cell growth, development, and immune regulation. This study delved into the microRNA expression profiles of yak milk-derived exosomes collected from both high- and low-altitude populations using small RNA sequencing.

A New '-morphotype' Species of Tube-Nosed Bat (Chiroptera: Vespertilionidae: ) from China.

During an examination of various specimens previously collected from different locations at different times, we discovered four specimens that had been collected in October and December 2023 from the Huanglianshan National Nature Reserve, Lvchun, Yunnan, China. Morphologically, these specimens can be distinguished from and other congeneric species based on a combination of body size, hair distribution, fur colour, and skull and teeth characteristics; molecularly, an analysis of Cyt and COI gene sequences showed that these specimens form a monophyletic group with with high posterior probability and bootstrap support values. Furthermore, the genetic distance between our specimens and was greater than the minimum threshold for interspecific differentiation, indicating that they are phylogenetically close but have diverged.

Effects of Dietary Protein Levels on Digestion, Metabolism, Serum Biochemical Indexes, and Rumen Microflora of Lanzhou Fat-Tailed Sheep.

This study aimed to investigate the effect of varying levels of dietary protein on digestion, metabolism, serum biochemical indexes, and rumen microflora in Lanzhou fat-tailed sheep. A total of twenty 8-month-old healthy rams with an initial average body weight (BW 25.16 ± 1.

Decomposing disparities in the utilization of basic public health services between locals and internal migrants in China: the role of social determinants.

Background: Internal migrants in China have long been at a disadvantage in terms of access to publicly financed services, as well as the utilization of public health services. The aim of the study was to examine inequities in the use of basic public health services between internal migrants and the local population and estimate the factors that contributed to inequity in use.

Methods: The data for this study was derived from the 2017 wave of the China Migrants Dynamic Survey.

Subsurface warming associated with Pacific Summer Water transport toward the Chukchi Borderland in the Arctic Ocean.

Recent rapid sea ice reduction in the Pacific sector of the Arctic Ocean is potentially associated with inflow of Pacific-origin water via the Bering Strait. For the first time, we detected remarkable subsurface warming around the Chukchi Borderland in the Arctic Ocean over the recent two decades (i.e.