J Neurosurg
January 2025
1Department of Neurosurgery, St. Olav's University Hospital, Trondheim, Norway.
Objective: The extent of resection (EOR) and postoperative residual tumor (RT) volume are prognostic factors in glioblastoma. Calculations of EOR and RT rely on accurate tumor segmentations. Raidionics is an open-access software that enables automatic segmentation of preoperative and early postoperative glioblastoma using pretrained deep learning models.
View Article and Find Full Text PDFEvol Comput
January 2025
College of Science, Northwest A&F University, Yangling 712100, China
Decomposition-based multi-objective evolutionary algorithms (MOEAs) are popular methods utilized to address many-objective optimization problems (MaOPs). These algorithms decompose the original MaOP into several scalar optimization subproblems, and solve them to obtain a set of solutions to approximate the Pareto front (PF). The decomposition approach is an important component in them.
View Article and Find Full Text PDFPlant Physiol
January 2025
Shaanxi Engineering Research Center for Vegetables/College of Horticulture, Northwest A&F University, Yangling, Shaanxi 712100, China.
Proper regulation of the source-sink relationship is an effective way to increase crop yield. Gibberellin (GA) is an important regulator of plant growth and development, and physiological evidence has demonstrated that GA can promote source-sink sucrose partitioning. However, the underlying molecular mechanism remains unclear.
View Article and Find Full Text PDFBiomed Res Int
January 2025
Department of Biology, College of Natural & Computational Sciences, University of Gondar, Gondar, Ethiopia.
Hepatitis and human immunodeficiency virus (HIV) are major public health issues in developing countries, including Ethiopia. These viruses can be transmitted from mother to child during birth or through contact with contaminated blood. In many areas of Ethiopia, viral hepatitis and HIV infections are significant health concerns for pregnant women.
View Article and Find Full Text PDFGratitude is associated with increased social integration, which may counter the loneliness stemming from repeated peer victimization. The gratitude youth feel after different types of bystander action may depend on which behaviors are most congruent with personal beliefs. Face and honor cultures provide social norms for expectations and interpretations of behavior, including how to act during and after interpersonal conflict.
View Article and Find Full Text PDFPlant Cell Environ
January 2025
Department of Geosciences and Natural Resource Management, University of Copenhagen, Frederiksberg, Denmark.
Common ash (Fraxinus excelsior) is under intensive attack from the invasive alien pathogenic fungus Hymenoscyphus fraxineus, causing ash dieback at epidemic levels throughout Europe. Previous studies have found significant genetic variation among genotypes in ash dieback susceptibility and that host phenology, such as autumn yellowing, is correlated with susceptibility of ash trees to H. fraxineus; however, the genomic basis of ash dieback tolerance in F.
View Article and Find Full Text PDFObes Surg
January 2025
Department of Surgery and Transplantation, University Hospital of Zurich, University of Zurich, Zurich, Switzerland.
Background: Roux-en-Y gastric bypass may present long-term complications that require revisional surgery or even reversal to normal anatomy. Data on the indications, surgical technique, and outcomes of RYGB reversal remain scarce.
Methods: We identified 48 cases of RYGB reversals with complete 90-day follow-up within a multi-centric international retrospective database of elective secondary bariatric surgery.
J Sci Food Agric
January 2025
College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.
Background: Dietary supplementation for beef cattle, using natural plant extracts, such as oregano essential oil (OEO), has proven effective in enhancing growth performance, beef production quantity and quality, and ensuring food safety. However, the precise mechanisms underlying these effects remain unclear. This study investigated the impact of OEO on carcass traits, muscle fiber structure, meat quality, oxidative status, flavor compounds, and gene regulatory mechanisms in the longissimus thoracis (LT) muscles of beef cattle.
View Article and Find Full Text PDFSci China Life Sci
January 2025
Laboratory of Animal Nutritional Physiology and Metabolic Process, Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, 410125, China.
Metabolites and metabolism-related gene expression profiles in skeletal muscle change dramatically under obesity, aging and metabolic disease. Since obese and lean pigs are ideal models for metabolic research. Here, we compared metabolome and transcriptome of Longissimus dorsi (LD) muscle between Taoyuan black (TB, obese) and Duroc (lean) pigs at different ages.
View Article and Find Full Text PDFPlant Mol Biol
January 2025
State Key Laboratory for Crop Stress Resistance and High-Efficiency Production and College of Plant Protection, Northwest A&F University, Yangling, 712100, China.
Psa primarily utilises the type III secretion system (T3SS) to deliver effector proteins (T3Es) into host cells, thereby regulating host immune responses. However, the mechanism by which kiwifruit responds to T3SS remains unclear. To elucidate the molecular reaction of kiwifruit plants to Psa infection, M228 and mutant M228△hrcS strains were employed to inoculate Actinidia chinensis var.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Quality Assurance and Laboratory Management, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
PLoS One
January 2025
School of Literature, Huaiyin Normal University, Huaian, China.
The fine-grained mining and construction of semantic associations within multimodal intangible cultural heritage (ICH) resources are crucial for deepening our understanding of their knowledge content and ensuring their systematic protection and transmission in the digital and intelligent era. This paper addresses the urgent need for the digital preservation and transmission of ICH resources. Following a review of current research on Qingyang sachets and ICH, the study introduces an ontology-based approach to constructing a semantic description model for the multimodal digital resources related to Qingyang sachets.
View Article and Find Full Text PDFEur J Trauma Emerg Surg
January 2025
Internal Medicine Department, Hospital Público de Monforte, Rua Corredoira s/n, Monforte de Lemos, 27400, Lugo, Spain.
Background: Hip fractures represent a serious public health problem with a high burden of mortality, morbidity, and resource use. Co-management has proven to enhance the clinical outcomes of hip fracture patients hospitalized in various settings.
Aim: This study aims to evaluate whether the previously observed benefits of co-management can be achieved when such a program is implemented in a rural-based district hospital.
J Evol Biol
January 2025
Laboratory of Walnut Research Center, College of Forestry, Northwest A & F University, Yangling, 712100 Shaanxi, China.
Walnut is a significant woody oil tree species that has been increasingly affected by anthracnose in recent years. Effective anthracnose control is crucial for walnut yield and quality, which requires a comprehensive understanding of the response mechanisms to Colletotrichum gloeosporioides. The PR10/Bet v1-like proteins are involved in defense against various disease, therefore, in this study, 7 JrBet v1s were identified from the walnut transcriptome (named JrBet v1-1~1-7), whose open reading frame (ORF) was 414~483 bp in length with isoelectric point ranging from 4.
View Article and Find Full Text PDFBMJ Open
January 2025
Department of Optometry, College of Medicine and Health Sciences, Comprehensive Specialized Hospital, University of Gondar, Gondar, Ethiopia.
Objective: Adaptive coping mechanisms (ACMs) are effective ways to cope with stress and anxiety in patients with chronic illnesses, such as glaucoma. This study aimed to assess the proportion of ACM and associated factors among adult glaucoma patients enrolled at the tertiary eye care and training centre in Northwest Ethiopia.
Design: An institution-based cross-sectional study.
BMJ Open
January 2025
Department of Plastic and Burn Surgery, Second Affiliated Hospital of Air Force Medical University, Xi'an, Shaanxi, China
Objective: This study aimed to assess the impact of the COVID-19 pandemic on the characteristics and outcomes of patients with burns in a burn centre situated in Northwest China.
Design: A retrospective descriptive study.
Setting: This study was conducted in Tangdu Hospital, a major regional burn centre in Xi'an, Shaanxi Province of China.
J Ovarian Res
January 2025
Shunyi Hospital, Beijing Traditional Chinese Medicine Hospital, Beijing, 101300, China.
Background: Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder in women of reproductive age. Anovulation is one of the most important clinical features of PCOS, and insulin resistance (IR) is one of the critical pathogenic factors. Woxuanzhongzhou (WXZZ) is a traditional herbal formulation that has shown efficacy in treating PCOS combined with IR, but the underlying mechanism is not clear.
View Article and Find Full Text PDFCurr Pharm Des
January 2025
Center of Bioinformatics, College of Life Sciences, Northwest Agriculture and Forestry University, Yangling, Shaanxi, 712100, China.
Introduction: The COVID-19 pandemic has necessitated rapid advancements in therapeutic discovery. This study presents an integrated approach combining machine learning (ML) and network pharmacology to identify potential non-covalent inhibitors against pivotal proteins in COVID-19 pathogenesis, specifically B-cell lymphoma 2 (BCL2) and Epidermal Growth Factor Receptor (EGFR).
Method: Employing a dataset of 13,107 compounds, ML algorithms such as k-Nearest Neighbors (kNN), Support Vector Machine (SVM), Random Forest (RF), and Naïve Bayes (NB) were utilized for screening and predicting active inhibitors based on molecular features.
Background: The transmission of Salmonella spp. to human through the consumption of contaminated food products of animal origin, mainly poultry is a significant global public health concern. The emerging multidrug resistant (MDR) clones of non-typhoidal Salmonella (NTS) serovars, have spread rapidly worldwide both in humans and in the food chain.
View Article and Find Full Text PDFBiotechnol Biofuels Bioprod
January 2025
Department of Animal Science and Technology, University of Northwest A&F, Yangling, 712100, Shaanxi, China.
Antimicrobial peptides (AMPs) are renowned for their potent bacteriostatic activity and safety, rendering them invaluable in animal husbandry, food safety, and medicine. Despite their potential, the physiological toxicity of AMPs to host cells significantly hampers their biosynthetic production. This study presents a novel approach for the biosynthesis of the antimicrobial peptide Kiadin by engineering a DAMP4-DPS-Kiadin fusion protein to mitigate host cell toxicity and achieve high-level expression.
View Article and Find Full Text PDFBMC Geriatr
January 2025
Department of Electronic and Electrical Engineering, University of Liverpool, 9 Brownlow Hill, Liverpool, UK.
Background: Brain-computer interface (BCI) offers promising solutions to cognitive enhancement in older people. Despite the clear progress received, there is limited evidence of BCI implementation for rehabilitation. This systematic review addresses BCI applications and challenges in the standard practice of EEG-based neurofeedback (NF) training in healthy older people or older people with mild cognitive impairment (MCI).
View Article and Find Full Text PDFJ Phys Chem Lett
January 2025
Department of Physics and Astronomy and Thomas Young Centre, University College London, London WC1E 6BT, United Kingdom.
Atomic-scale understanding of important geochemical processes including sorption, dissolution, nucleation, and crystal growth is difficult to obtain from experimental measurements alone and would benefit from strong continuous progress in molecular simulation. To this end, we present a reactive neural network potential-based molecular dynamics approach to simulate the interaction of aqueous ions on mineral surfaces in contact with liquid water, taking Fe(II) on hematite(001) as a model system. We show that a single neural network potential predicts rate constants for water exchange for aqueous Fe(II) and for the exergonic chemisorption of aqueous Fe(II) on hematite(001) in good agreement with experimental observations.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China.
Attributable to sulfur's significant theoretical energy density, its affordability, and its environmentally friendly nature, lithium-sulfur batteries (LSBs) are recognized as advanced energy storage technologies with considerable potential. Nonetheless, the solubility and migration of polysulfides within the electrolyte substantially hinder their practical implementation. To address this issue, we developed a nitrogen-doped two-dimensional (2D) wavy carbon nanosheet material (NCN) by using the Pickering emulsion templating method.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
State Key Laboratory of Crop Stress Biology for Arid Areas, College of Agronomy, Northwest A & F University, Yangling 712100, Shaanxi, China. Electronic address:
Sci Total Environ
January 2025
Key Laboratory of Cryospheric Science and Frozen Soil Engineering, Northwest Institute of Eco-Environment and Resources, Chinese Academy of Sciences, Lanzhou 730000, China.
The inadequacy of current emission reduction measures necessitates exploring innovative approaches to address the critical issue of ice sheet and mountain glacier melting. Geoengineering emerges as a potential solution to mitigate severe cryospheric changes. This review systematically examines geoengineering techniques tailored to ice sheets and mountain glaciers, analyzing their efficacy, risks, and limitations based on existing literature.
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