Intervention Techniques Targeting Echolalia: A Scoping Review.

Purpose: Although echolalic speech is found in typical development, echolalia is most commonly associated with autism. As such, echolalia has frequently been the focus of various interventions aimed at autistic children. Recent research and the voices of autistic self-advocates indicate that echolalia serves as a meaningful form of communication or functionally supports self-regulation.

Using a smartphone app to monitor Raynaud's attacks and quantify skin colour changes-towards objective outcome measures for Raynaud's.

Objectives: Our overall aim was to develop a smartphone app to collect photographic images of Raynaud's phenomenon (RP) attacks alongside patient reported outcome measures (PROMs). Specific objectives included assessing the feasibility of patients documenting RP attacks using mobile phones, developing image analysis methods to document colour change, and comparing photographic parameters to 'non-imaging' app and paper diary parameters.

Methods: Study 1: 36 patients with systemic sclerosis (SSc)-related RP photographed RP attacks over 15 days as well as completing an RP paper diary.

Four-Centre, Multi-Electron Bonding in Rare-Earth Germole Sandwich Complexes.

Reduction of the germole-ligated sandwich complexes [(η5-CpGe)M(η5-Cpttt)]2 (1M, M = Y, Gd, Dy) with one or two equivalents of KC8/2.2.2-cryptand produces [(η5-CpGe)M(η5-Cpttt)2]- (2M) and [(η5-CpGe)M(η5-Cpttt)2]2- (3M), respectively, as salts of [K(2.

A rhizobacterium-secreted protein induces lateral root development through the IAA34-PUCHI pathway.

Lateral roots (LRs) can continuously forage water and nutrients from soil. In Arabidopsis thaliana, LR development depends on a canonical auxin signaling pathway involving the core transcription factors INDOLE-3-ACETIC ACIDs (IAAs) and AUXIN RESPONSE FACTORs (ARFs). In this study, we identified a protein, bacillolysin, secreted by the beneficial rhizobacterium Bacillus velezensis SQR9, that is able to stimulate LR formation of Arabidopsis.

Policy decisions matter: Cessation of logging benefits 34 threatened species in Victoria, Australia.

In January 2024, the Australian state of Victoria committed to ending native forest logging six years ahead of schedule, a decision that has been advocated for by scientists and conservationists for decades. However, the direct benefits for threatened species from this policy change has not been quantified. This study assesses the spatial overlap between areas approved for logging and the habitats of nationally listed threatened species, to estimate the potential impacts of continued logging and the likely benefits of its cessation.

Genomic epidemiology of Plasmodium knowlesi reveals putative genetic drivers of adaptation in Malaysia.

Sabah, Malaysia, has amongst the highest burden of human Plasmodium knowlesi infection in the world, associated with increasing encroachment on the parasite's macaque host habitat. However, the genomic make-up of P. knowlesi in Sabah was previously poorly understood.

Total Synthesis of the Membrane Spanning Tetraether Lipid brGDGT Ia and Elucidation of its Stereochemical Configuration.

Glycerol dialkyl glycerol tetraethers (GDGTs) are a group of membrane spanning lipids produced by both Archaea and Bacteria. Branched GDGTs (brGDGTs) are a class of these tetraether lipids known to be produced by certain bacteria and are commonly found in terrestrial environments. Due to their environmental ubiquity, high preservation potential, and role in membrane adaptation, brGDGTs form the basis of many widely employed paleoenvironmental proxies.

Validation of Parental Reports in Assessing Idiopathic Toe Walking Using Quantitative In-Shoe Device Measurements.

Background: Toe walking is prevalent among children, affecting 5% to 24% of the pediatric population. Clinicians rely on parental reports of frequency of toe walking to guide clinical decision making and outcomes assessment. However, recall accuracy and differing environments challenge the reliability of parental reports.

New Polyhydroxysteroids Derivatives from Starfish Asterias amurensis Induce Embryotoxicity in Marine Medaka.

In recent years, multiple population outbreaks of the Northern Pacific starfish (Asterias amurensis) have been documented off the coast of Qingdao. Starfish use chemosensation to regulate their life history and interactions with the environment, with their secondary metabolites serving as deterrents and dispersal agents against predators. While the eggs of marine fish are passive and susceptible, we hypothesized that the secondary metabolites of A.

The impact of cold spells and heat waves frequencies on the prevalence and incidence of stroke in middle-to-elderly age population in China: evidence from the China Health and Retirement Longitudinal Study (CHARLS).

Stroke, a key cardiovascular disease, is impacted by cold spells and heat waves. However, limited sample size and unclear impact on the aging population's prevalence and incidence remain concerns. We aim to explore the association between cold spells and heat waves frequency and stroke in middle-aged and elderly people in China.

Impacts of spring freeze events on a perennial tree fruit crop across the central and eastern USA.

This study uses a crop simulation model driven by 40 years (1981-2020) of daily gridded meteorological data from PRISM to assess the impacts of spring freeze events on cherry trees, a representative temperate perennial tree-fruit crop, across six regions of the central and eastern USA: the Northern and Southern Great Plains (NGP, SGP), Upper Midwest (UMW), Ohio Valley (OHV), New York-Pennsylvania (NY-PA), and Virginia-North Carolina (VA-NC). Freeze damage exhibits a clear latitudinal gradient, with damage frequency and severity decreasing from south to north. The most frequent and severe damage occurs in the SGP, followed by VA-NC, while the least is observed in the UMW and NY-PA.

Gastric Cancer Screening in the United States: A Review of Current Evidence, Challenges, and Future Perspectives.

Gastric cancer remains a leading cause of cancer-related mortality worldwide. In the United States, gastric cancer incidence and mortality are substantially higher among non-White racial and ethnic groups and new immigrants from high-incidence countries. This is in large part related to the higher prevalence of Helicobacter pylori-associated gastric premalignant changes in these populations.

ACG Clinical Guideline: Diagnosis and Management of Gastric Premalignant Conditions.

Gastric premalignant conditions (GPMC) are common and include atrophic gastritis, gastric intestinal metaplasia, dysplasia, and certain gastric epithelial polyps. GPMC have an increased risk of progression to gastric adenocarcinoma. Gastric cancer (GC) in the United States represents an important cancer disparity because incidence rates are 2- to 13-fold greater in non-White individuals, particularly early-generation immigrants from regions of high GC incidence.

Demystifying Meckel's diverticulum - a guide for the gastroenterologist.

Purpose Of Review: Meckel's diverticulum (MD) is a common congenital ileal diverticulum. Whilst mostly asymptomatic, 4-9% develop complications, such as small bowel obstruction, diverticulitis or bleeding. In 1933, Charles Mayo wrote that MD is 'frequently suspected, often looked for and seldom found', and it continues to pose a diagnostic challenge today.

Estimated Cancer Risk in Females Who Meet the Criteria to Exit Cervical Cancer Screening.

Importance: Cervical screening guidelines in the US recommend that most females can exit routine screening at age 65 years following 2 recent consecutive negative cotest results (concurrent human papillomavirus and cytology tests). However, empirical data on the subsequent risks of cancer and cancer death in this subgroup of females are limited.

Objective: To estimate the risks of cervical cancer and cervical cancer death among females who meet the cotesting criteria to exit screening.

Novel Non-Destructive Detection Methods for in Northern Red Oak and Chestnut.

Oak wilt, caused by the fungal pathogen , spreads via root grafts and insect vectors, threating oaks ( spp.) and chestnuts ( spp.) in the United States.

Investigating the Degradation of Historical Man-Made Cellulose-Derived Textiles via Accelerated Ageing.

Cellulose-derived materials, like paper and cellulose acetate, are known to be vulnerable to degradation within museum collections. Studies have been conducted and degradation markers have been identified on these materials. However, the degradation of man-made cellulose-derived fibres in collections is not well understood.

Preserving the Biologically Coherent Generic Concept of , 'Plant Destroyer'.

is a long-established, well known and globally important genus of plant pathogens. Phylogenetic evidence has shown that the biologically distinct, obligate biotrophic downy mildews evolved from at least twice. Since, cladistically, this renders 'paraphyletic', it has been proposed that evolutionary clades be split into multiple genera (Runge et al.

Infection by Clonally Related Isolates: The Role of Drinking Water.

Rationale: group bacteria (MABS) cause lethal infections in people with chronic lung diseases. Transmission mechanisms remain poorly understood; the detection of dominant circulating clones (DCCs) has suggested potential for person-to-person transmission.

Objectives: This study aimed to determine the role of drinking water in the transmission of MABS.

Endocrine therapy and risk of cardiovascular disease and mortality in postmenopausal breast cancer survivors.

Background: There are increasing concerns of cardiovascular safety related to endocrine therapy use in women with breast cancer (BC). We examined risk of cardiovascular disease (CVD) events and mortality associated with endocrine therapy use in postmenopausal women with early-stage BC.

Methods: Postmenopausal women diagnosed with stage I-III hormone receptor-positive BC from 2005 to 2013 were included (n = 8,495).

Infraslow fluctuations of sustained attention in mood disorders.

Background: Sustained attention is integral to goal-directed tasks in everyday life. It is a demanding and effortful process prone to failure. Deficits are particularly prevalent in mood disorders.

Recent Advances in Paper-Based Nano-Biosensors for Water-Borne Pathogen Detection: Challenges and Solutions.

Ensuring access to safe water and public health necessitates sensitive, quick, and dependable detection instruments. Conventional techniques frequently have prolonged detection durations, intricate processes, and the requirement for skilled staff. Biosensors augmented with nanomaterials provide enhanced sensitivity, specificity, and rapid detection of waterborne pathogens.

2024 ASCO guidelines for the prevention and management of osteoradionecrosis in patients with head & neck cancer treated with radiation therapy.

Purpose Of Review: Osteoradionecrosis may often be prevented in context of interprofessional healthcare that includes dental specialists prior to and following completion of the patient's head and neck radiation therapy. Important factors, however, compromise delivery of guideline-concordant management of osteoradionecrosis (ORN), including patient access to this interprofessional care. This review is directed to these and related issues, in order to foster enhanced approaches for ORN management.

Are internal migrants (head porters) sexually vulnerable due to the coronavirus pandemic? A qualitative study of the situation in Ghana.

Head porterage, popularly known in Ghana as Kayayei, has been an old economic venture for young girls and women who migrate from the northern to the southern part of the country. Even though Head Porters view Kayayei as a source of livelihood, conditions such as the outbreak of the 2019 coronavirus disease (COVID-19) further worsened their sexual vulnerabilities, as well as their autonomy to make decisions on contraceptive use. Head Porters, as a term defined in this study, refers to women aged 15 years or older who carry loads from one point of the town to another for a fee.