Demystifying Meckel's diverticulum - a guide for the gastroenterologist.

Purpose Of Review: Meckel's diverticulum (MD) is a common congenital ileal diverticulum. Whilst mostly asymptomatic, 4-9% develop complications, such as small bowel obstruction, diverticulitis or bleeding. In 1933, Charles Mayo wrote that MD is 'frequently suspected, often looked for and seldom found', and it continues to pose a diagnostic challenge today.

Estimated Cancer Risk in Females Who Meet the Criteria to Exit Cervical Cancer Screening.

Importance: Cervical screening guidelines in the US recommend that most females can exit routine screening at age 65 years following 2 recent consecutive negative cotest results (concurrent human papillomavirus and cytology tests). However, empirical data on the subsequent risks of cancer and cancer death in this subgroup of females are limited.

Objective: To estimate the risks of cervical cancer and cervical cancer death among females who meet the cotesting criteria to exit screening.

Novel Non-Destructive Detection Methods for in Northern Red Oak and Chestnut.

Oak wilt, caused by the fungal pathogen , spreads via root grafts and insect vectors, threating oaks ( spp.) and chestnuts ( spp.) in the United States.

Investigating the Degradation of Historical Man-Made Cellulose-Derived Textiles via Accelerated Ageing.

Cellulose-derived materials, like paper and cellulose acetate, are known to be vulnerable to degradation within museum collections. Studies have been conducted and degradation markers have been identified on these materials. However, the degradation of man-made cellulose-derived fibres in collections is not well understood.

Preserving the Biologically Coherent Generic Concept of , 'Plant Destroyer'.

is a long-established, well known and globally important genus of plant pathogens. Phylogenetic evidence has shown that the biologically distinct, obligate biotrophic downy mildews evolved from at least twice. Since, cladistically, this renders 'paraphyletic', it has been proposed that evolutionary clades be split into multiple genera (Runge et al.

Infection by Clonally Related Isolates: The Role of Drinking Water.

Rationale: group bacteria (MABS) cause lethal infections in people with chronic lung diseases. Transmission mechanisms remain poorly understood; the detection of dominant circulating clones (DCCs) has suggested potential for person-to-person transmission.

Objectives: This study aimed to determine the role of drinking water in the transmission of MABS.

Endocrine therapy and risk of cardiovascular disease and mortality in postmenopausal breast cancer survivors.

Background: There are increasing concerns of cardiovascular safety related to endocrine therapy use in women with breast cancer (BC). We examined risk of cardiovascular disease (CVD) events and mortality associated with endocrine therapy use in postmenopausal women with early-stage BC.

Methods: Postmenopausal women diagnosed with stage I-III hormone receptor-positive BC from 2005 to 2013 were included (n = 8,495).

Infraslow fluctuations of sustained attention in mood disorders.

Background: Sustained attention is integral to goal-directed tasks in everyday life. It is a demanding and effortful process prone to failure. Deficits are particularly prevalent in mood disorders.

Recent Advances in Paper-Based Nano-Biosensors for Water-Borne Pathogen Detection: Challenges and Solutions.

Ensuring access to safe water and public health necessitates sensitive, quick, and dependable detection instruments. Conventional techniques frequently have prolonged detection durations, intricate processes, and the requirement for skilled staff. Biosensors augmented with nanomaterials provide enhanced sensitivity, specificity, and rapid detection of waterborne pathogens.

2024 ASCO guidelines for the prevention and management of osteoradionecrosis in patients with head & neck cancer treated with radiation therapy.

Purpose Of Review: Osteoradionecrosis may often be prevented in context of interprofessional healthcare that includes dental specialists prior to and following completion of the patient's head and neck radiation therapy. Important factors, however, compromise delivery of guideline-concordant management of osteoradionecrosis (ORN), including patient access to this interprofessional care. This review is directed to these and related issues, in order to foster enhanced approaches for ORN management.

Are internal migrants (head porters) sexually vulnerable due to the coronavirus pandemic? A qualitative study of the situation in Ghana.

Head porterage, popularly known in Ghana as Kayayei, has been an old economic venture for young girls and women who migrate from the northern to the southern part of the country. Even though Head Porters view Kayayei as a source of livelihood, conditions such as the outbreak of the 2019 coronavirus disease (COVID-19) further worsened their sexual vulnerabilities, as well as their autonomy to make decisions on contraceptive use. Head Porters, as a term defined in this study, refers to women aged 15 years or older who carry loads from one point of the town to another for a fee.

Effects of cooperative learning on undergraduate nursing students: a quasi- experimental study.

Aim: This study evaluated the effect of cooperative learning on the attitude, satisfaction, and performance of undergraduate nursing students enrolled in community nursing courses.

Design: A one-group pretest-posttest quasi-experimental design.

Methods: This study was conducted at a university in northern Taiwan.

Comparing the efficacy and safety of bridging therapy vs. monotherapy in patients with minor stroke: a meta-analysis.

The two main therapeutic approaches for stroke treatment are endovascular thrombectomy, which involves mechanically removing the thrombus, and bridging therapy, which uses intravenous thrombolytics (IVT) prior to endovascular thrombectomy (EVT). This study aimed to compare monotherapy (EVT or IVT alone) with bridging therapy (IVT+EVT) in terms of efficacy and safety outcomes in patients with minor ischemic stroke. After a thorough screening, eight studies were included for qualitative synthesis and meta-analysis, comprising a total of 3,117 patients across the treatment arms.

Derivation and Internal Validation of a Clinical Prediction Model for Diagnosis of Spotted Fever Group Rickettsioses in Northern Tanzania.

Spotted fever group rickettsioses (SFGR) pose a global threat as emerging zoonotic infectious diseases; however, timely and cost-effective diagnostic tools are currently limited. We used data from 449 patients presenting to 2 hospitals in northern Tanzania between 2007 and 2008, of which 71 (15.8%) met criteria for acute SFGR based on ≥4-fold rise in antibody titers between acute and convalescent serum samples.

Prognostic role of p16 overexpression in sinonasal squamous cell carcinoma: A retrospective analysis of Alberta patients.

Objective: Sinonasal squamous cell carcinoma (SNSCC) is rare in the general population. No clear and consistent etiologic correlation between human papillomavirus (HPV) and SNSCC has yet been delineated in the literature. p16 is a tumor suppressor protein used as a surrogate marker for HPV.

The membrane may be a key factor influencing browning: a mini review on browning mechanisms of fresh-cut fruit and vegetables from a multi-omics perspective.

Fresh-cut fruit and vegetables are susceptible to browning during storage and subsequent consumption. The cell membrane acts as a vital structural barrier, compartmentalizing various substances within living organisms. The fresh-cutting process induces mechanical injuries, disrupting these membranes and resulting in the leakage of cellular contents.

Distinct spatiotemporal atrophy patterns in corticobasal syndrome are associated with different underlying pathologies.

Although the corticobasal syndrome was originally most closely linked with the pathology of corticobasal degeneration, the 2013 Armstrong clinical diagnostic criteria, without the addition of aetiology-specific biomarkers, have limited positive predictive value for identifying corticobasal degeneration pathology in life. Autopsy studies demonstrate considerable pathological heterogeneity in corticobasal syndrome, with corticobasal degeneration pathology accounting for only ∼50% of clinically diagnosed individuals. Individualized disease stage and progression modelling of brain changes in corticobasal syndrome may have utility in predicting this underlying pathological heterogeneity, and in turn improve the design of clinical trials for emerging disease-modifying therapies.

Complex relationship between soil fungi and conservation value assessments in boreal forests.

Large-scale industrial forestry is a threat to biodiversity and imposes long-lasting changes to many forested biomes. Preserving forests as reserves is an important component of the strategy for safeguarding forest biodiversity. Yet, the selection of forests of high biodiversity value is usually based on proxies (i.

Genome-wide selection scans in Mexican Indigenous populations reveal recent signatures of pathogen and diet adaptation.

Whole genome scans for natural selection signatures across Mexican Indigenous (MI) Populations remain underrepresented in the literature. Here, we conducted the first comparative analysis of genetic adaptation in MI populations using whole genome sequencing (WGS) data from 76 individuals representing 27 different ethnic groups in Mexico. We divided the cohort into Northern, Central, and Southern populations and identified signals of natural selection within and across populations.

Ethical boundaries and data-sharing practices in AI-enhanced nursing: An Arab perspective.

Aim: This study explored the ethical boundaries and data-sharing practices in artificial intelligence (AI)-enhanced nursing from the perspective of Arab nurses.

Background: Although AI offers advancements in clinical decision-making and operational efficiency, it also presents challenges such as ethical dilemmas, data privacy concerns, and technical issues. These challenges are being addressed through continuous education, the development of robust ethical guidelines, and the implementation of transparent data-sharing practices METHODS: A qualitative approach was employed, adhering to the Standards for Reporting Qualitative Research (SRQR) guidelines.

Fetal exposure to gestational diabetes severity and postnatal infant feeding in the first year of life associated with preadolescent obesity: a prospective cohort.

Objective: This study sought to evaluate the distinct impact of fetal exposure to gestational diabetes (GDM) severity, as well as the impact of infant breastfeeding (BF) and sugary beverage intake, on preadolescent overweight and obesity, accounting for other established risk factors.

Methods: This analysis included 850 mother-infant dyads exposed to GDM who reported monthly infant BF duration and intensity, as well as sugary beverage intake (sugar-sweetened beverages [SSB] and 100% fruit juice [FJ]) during the first year of life, BMI measured at ages 6 to 11 years, and GDM severity variables (i.e.

Validation of the Sudbury Vertigo Risk Score to risk stratify for a serious cause of vertigo.

Introduction: In 2022, nearly 0.5 million Canadians visited an emergency department (ED) for dizziness, accounting for over 3.5% of all ED visits.

Global Greening Major Contributed by Climate Change With More Than Two Times Rate Against the History Period During the 21th Century.

Future variations of global vegetation are of paramount importance for the socio-ecological systems. However, up to now, it is still difficult to develop an approach to project the global vegetation considering the spatial heterogeneities from vegetation, climate factors, and models. Therefore, this study first proposes a novel model framework named GGMAOC (grid-by-grid; multi-algorithms; optimal combination) to construct an optimal model using six algorithms (i.

Consideration of evidence-based training content to strengthen coach recognition of concussion during youth sports activities.

Objective: To synthesize requirements and recommendations addressing sport-related concussion (SRC).

Design: Qualitative study.

Setting: Scholastic and non-scholastic athletic programs.