1 results match your criteria: "Northern Arizona University (P.K.)[Affiliation]"
Plasma metagenomic sequencing to detect and quantify bacterial DNA in ICU patients suspected of sepsis: A proof-of-principle study.
J Trauma Acute Care Surg
December 2021
From the Center for Noninvasive Diagnostics (M.T.K., A.O.-B., H.M., S.N.S., T.C.-C., M.M.), Translational Genomics Research Institute, Phoenix; Department of Surgery (M.T.K., B.J., Z.K., T.O., P.R.), University of Arizona, Tucson, Arizona; Department of Surgery (M.T.K., R.A., A.S.), Brigham and Women's Hospital, Boston, Massachusetts; and Pathogen and Microbiome Institute, Northern Arizona University (P.K.), Flagstaff, Arizona.
Article Synopsis
- The study explores using metagenomic sequencing to analyze bacterial DNA in plasma for early detection of sepsis in critically ill patients.
- The research involved 30 patients, analyzing 72 plasma samples over time, showing higher bacterial DNA levels in samples collected during active infections.
- The findings suggest that measuring bacterial DNA levels can identify and monitor infections more accurately than traditional microbial cultures, potentially improving patient outcomes.