40,505 results match your criteria: "Northeastern University; Brigham & Women's Hospital[Affiliation]"

The NASICON-type NaV(PO) (NVP) is recognized as a potential cathode material for Na-ion batteries (SIBs). Nevertheless, its inherent small electronic conductivity induces limited cycling stability and rate performance. Carbon coating, particularly N-doped carbon, has been identified as an effective strategy to address these challenges.

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Background: The global burden of HIV and AIDS continues to significantly impact public health, particularly in Sub-Saharan Africa. This study investigates the spatial distribution and associated risk factors of HIV prevalence in Botswana using data from the 2021 Botswana AIDS Impact Survey (BAIS V).

Methods: The analysis included 12,653 adults aged 15-64 years and employed chi-square tests, multilevel mixed-effects regression, and spatial analysis techniques.

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Based on the symmetric initiation mechanism of double-wing cracks in coal rock mass induced by high-pressure electro-recoil water pressure, fracturing experiments have been performed on coal rock mass under different water pressures and discharge conditions using high-voltage electric pulse hydraulic fracturing devices. Combined with CT scans, the crack spatial distribution inside the post-break coal rock mass was analyzed and found that the edge of the water injection hole is prone to produce double-wing cracks along the drilling hole diameter. ABAQUS is used to verify the physical test and extend the test conditions, the geometric parameter change, morphological expansion rule and crack initiation mechanism of double-wing crack in coal rock mass under different discharge conditions and ground stress conditions are studied.

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Delayed onset of ocean acidification in the Gulf of Maine.

Sci Rep

January 2025

Department of Botany, Smithsonian Institution, National Museum of Natural History, Washington, DC, 20013, USA.

The Gulf of Maine holds significant ecological and economic value for fisheries and communities in north-eastern North America. However, there is apprehension regarding its vulnerability to the effects of increasing atmospheric CO. Substantial recent warming and the inflow of low alkalinity waters into the Gulf of Maine have raised concerns about the impact of ocean acidification on resident marine calcifiers (e.

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Membranes have extensive applications in catalysis, separation, antimicrobial activities, and sensing. However, developing a simple and environmentally friendly method for preparing membranes remains challenging. Here, we report a novel strategy for fabricating self-standing inorganic-organic composite films at the miscible liquid/liquid interface using a soft spray technique.

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Cancer is a leading cause of death worldwide and its treatment is hampered by the lack of specificity and side effects of current drugs. Cardiotonic steroids (CTS) interact with Na/K-ATPase (NKA) and induce antineoplastic effects, but their narrow therapeutic window is key limiting factor. The synthesis of digitoxigenin derivatives with glycosidic unit modifications is a promising approach to develop more selective and effective antitumor agents.

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Introduction: Birthing people around the world experience mistreatment during labor and birth, contributing to adverse maternal health outcomes. The adoption of respectful maternity care (RMC) has been recommended to address this mistreatment and improve care quality. Most RMC and mistreatment research has been conducted internationally.

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Environment and management jointly shape the spatial patterns of plant species diversity of moist grasslands in the mountains of northeastern Yunnan.

Plant Divers

November 2024

College of Urban and Environmental Sciences, MOE Key Laboratory of Earth Surface Processes, Peking University, Beijing 100871, China.

Grasslands account for about a quarter of the Earth's land area and are one of the major terrestrial ecosystems, with significant ecological and economic values. The influence of environmental factors and management types on grassland biodiversity has garnered considerable attention. This study investigated how patterns of species richness are influenced by geographical distance, environmental gradients, and management type in the moist mountain grasslands of northeastern Yunnan, China.

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Genetic structure of populations in wildlife of north and northeast Iran.

Int J Parasitol Parasites Wildl

April 2025

Department of Medical Parasitology & Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

is a parasite prevalent in the temperate regions of the vast Palearctic realm, including Iran. In this study, we investigated infection in road-killed animals and carcasses in northern and northeastern Iran by artificial digestion. We assessed species identification and intraspecific genetic diversity using the markers 5S ribosomal DNA intergenic spacer (5S rDNA), internal transcribed spacer I (ITS1), and cytochrome oxidase subunit I ().

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Introduction: Physical Activity (PA) and its links to frailty, quality of life (QoL), and other comorbidities in older Ugandans living with HIV remain under-explored.

Methods: We analyzed data from three annual assessments of older people living with HIV (PLWH) and age- and sex-similar people not living with HIV (PnLWH). We fitted linear generalized estimating equations (GEE) regression models to estimate the correlates of PA, including demographics, frailty, QoL, HIV, and other comorbidities.

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Left ventricular systolic dysfunction (LVSD) and its severity are correlated with the prognosis of cardiovascular diseases. Early detection and monitoring of LVSD are of utmost importance. Left ventricular ejection fraction (LVEF) is an essential indicator for evaluating left ventricular function in clinical practice, the current echocardiography-based evaluation method is not avaliable in primary care and difficult to achieve real-time monitoring capabilities for cardiac dysfunction.

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Purpose: Despite recent advances, gender inequality remains a major concern within the workforce. One manifestation of gender inequality in academia is the undercitation of women-authored compared to men-authored papers that is thought to reflect implicit biases and has important implications for the academic advancement for research-intensive female faculty. These studies largely stem from male-dominant professions.

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Previous research has shown that students employ intuitive thinking when understanding scientific concepts. Three types of intuitive thinking-essentialist, teleological, and anthropic thinking-are used in biology learning and can lead to misconceptions. However, it is unknown how commonly these types of intuitive thinking, or cognitive construals, are used spontaneously in students' explanations across biological concepts and whether this usage is related to endorsement of construal-consistent misconceptions.

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Energy and water are interlinked and inseparable resources of vital importance to the survival and development of human society. Exploring the relationship between energy and water is of great practical significance for the sustainable development of resources. The uneven regional distribution of energy and water in China has exacerbated energy-related water shortages.

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Discovering electrocatalysts that can efficiently convert carbon dioxide (CO) to valuable fuels and feedstocks using excess renewable electricity is an emergent carbon-neutral technology. A single metal atom embedded in doped graphene, , single-atom catalyst (SAC), possesses high activity and selectivity for electrochemical CO reduction (COR) to CO, yet further reduction to hydrocarbons is challenging. Here, using density functional theory calculations, we investigate stability and reactivity of a broad SAC chemical space with various metal centers (3d transition metals) and dopants (2p dopants of B, N, O; 3p dopants of P, S) as electrocatalysts for COR to methane and methanol.

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Research demonstrates a positive impact of Peer Based Recovery Support Services (PBRSS) facilitated by peer recovery specialists (PRS), who are people in recovery from behavioral health conditions (e.g., substance use disorders [SUD] and mental health conditions).

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The offering of grocery stores is a strong driver of consumer decisions. While highly processed foods such as packaged products, processed meat and sweetened soft drinks have been increasingly associated with unhealthy diets, information on the degree of processing characterizing an item in a store is not straightforward to obtain, limiting the ability of individuals to make informed choices. GroceryDB, a database with over 50,000 food items sold by Walmart, Target and Whole Foods, shows the degree of processing of food items and potential alternatives in the surrounding food environment.

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All-angle unidirectional flat-band acoustic metasurfaces.

Nat Commun

January 2025

Department of Electrical and Computer Engineering, National University of Singapore, Singapore, Singapore.

Flat bands have empowered novel phenomena such as robust canalization with strong localization, high-collimation and low-loss propagation. However, the spatial symmetry protection in photonic or acoustic lattices naturally forces flat bands to manifest in pairs aligned at an inherently specific angle, resulting in a fixed bidirectional canalization. Here, we report an acoustic flat-band metasurface, allowing not only unidirectional canalization at all in-plane angles but also robust tunability in band alignment.

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Microwave synthesis of molybdenum disulfide quantum dots and the application in bilirubin sensing.

Methods Appl Fluoresc

January 2025

Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, No.36 Sanhao Street, Heping District, Shenyang, Liaoning Province, China, Shenyang, 110004, CHINA.

Molybdenum disulfide quantum dots (MoS2 QDs) is a new type of graphite like nanomaterial, which exhibited well chemical stability, unique fluorescence characteristics, and excellent biocompatibility. The conventional hydrothermal synthesis of MoS2 generally requires a long-term reaction at high temperature and high pressure. Herein, we have developed a simple and fast MoS2 QDs synthesis scheme using microwave heating, and further modified the surface of MoS2 QDs using 3-aminophenylboronic acid.

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Introduction: Visceral leishmaniasis (VL) also known as Kala-azar is one of the neglected tropical diseases (NTD) of public health importance. Despite being a disease of a long history, the condition remains poorly studied especially in East Africa. For instance, whereas, the geographical location of the disease is known, there is a stark paucity of data on the burden, risk factors and clinical outcomes of this contribution in Northeastern Uganda.

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The nexus between the business environment and high-quality economic development is pivotal for fostering sustainable growth. This study delves into their interrelationship, recognizing its profound practical significance. We have developed a comprehensive index system to evaluate high-quality economic development, encompassing four key dimensions: green development quality, robust economic growth, innovation dynamics, and equitable societal benefits.

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Background: Improving adherence to pre-exposure prophylaxis (PrEP) via digital health interventions (DHIs) for young sexual and gender minority men who have sex with men (YSGMMSM) is promising for reducing the HIV burden. Measuring and achieving effective engagement (sufficient to solicit PrEP adherence) in YSGMMSM is challenging.

Objective: This study is a secondary analysis of the primary efficacy randomized controlled trial (RCT) of Prepared, Protected, Empowered (P3), a digital PrEP adherence intervention that used causal mediation to quantify whether and to what extent intrapersonal behavioral, mental health, and sociodemographic measures were related to effective engagement for PrEP adherence in YSGMMSM.

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Lanthanide-Assisted Function Tailoring of the HOF-Based Logic Gate Sensor Array for Biothiol Detection and Disease Discrimination.

Anal Chem

January 2025

Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Box 332, Shenyang 110819, China.

The advancement of lanthanide fingerprint sensors characterized by targeted emission responses and low self-fluorescence interference for the detection of biothiols is of considerable importance for the early diagnosis and treatment of cancer. Herein, the lanthanide "personality function tailoring" HOF composite sensor array is designed for the specific discrimination of biothiols (GSH, Cys, and Hcy) based on the activation of various luminescent molecules, such as r-AuNCs/luminol via HOF surface proximity. Lumi-HOF@Ce serves as a versatile platform for catalyzing the oxidation of -phenylenediamine (OPD) to generate yellow fluorescent oligomers, accompanied by the fluorescence attenuation of luminol.

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Clair3-RNA: A deep learning-based small variant caller for long-read RNA sequencing data.

bioRxiv

January 2025

Department of Computer Science, School of Computing and Data Science, University of Hong Kong, Hong Kong, China.

Variant calling using long-read RNA sequencing (lrRNA-seq) can be applied to diverse tasks, such as capturing full-length isoforms and gene expression profiling. It poses challenges, however, due to higher error rates than DNA data, the complexities of transcript diversity, RNA editing events, etc. In this paper, we propose Clair3-RNA, the first deep learning-based variant caller tailored for lrRNA-seq data.

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Honey is a natural product gathered by honeybees from the pollen and nectar of various plants and flowers. The homeland of the Caucasian honey bee, which draws attention with its honey production and is one of the most productive bee races known in the world, is Northeastern Anatolia in Türkiye. This study aims to determine and correlate the phenolic content and antioxidant activity of 54 honey samples obtained from the most important gene centers of the Caucasian bee in Türkiye.

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