Benefit of the Omental Flap in Breast Reconstruction for Oncoplastic Treatment: A Systematic Review and Single-Arm Meta-Analysis.

Background: Oncoplastic surgery for breast cancer patients poses the challenge of achieving optimal aesthetic outcomes without increasing the risk of complications. Omental flap has emerged as n reconstructive option in breast surgery, yet the efficacy and safety of large omental flaps remain uncertain. This study aims to conduct a systematic review and single-arm meta-analysis to comprehensively evaluate the effectiveness, safety, and cosmetic outcomes of large omental flap breast reconstruction, providing updated evidence for clinical practice.

Joint extraction of entity and relation based on fine-tuning BERT for long biomedical literatures.

Motivation: Joint extraction of entity and relation is an important research direction in Information Extraction. The number of scientific and technological biomedical literature is rapidly increasing, so automatically extracting entities and their relations from these literatures are key tasks to promote the progress of biomedical research.

Results: The joint extraction of entity and relation model achieves both intra-sentence extraction and cross-sentence extraction, alleviating the problem of long-distance information dependence in long literature.

Detachable Cyclic Poly(ethylene glycol)-Embedded Choline Phosphate Liposome Used for Long-Acting and Accurate Cancer Chemo-Immunotherapy with High Security.

Liposomes have attracted attention in biomedicine and pharmacy for their benefits including reduced toxicity, extended pharmacokinetics, and biocompatibility. However, their limitations include susceptibility to blood clearance, rapid disintegration, and lack of functionality, restricting their further applications. To address these challenges, inspired by the unique topological features of cyclic polymers and the specific binding property of the choline phosphate (CP) lipid, dipole-dipole interactions between CP molecules are utilized to create a detachable cyclic PEG-embedded CP liposome (d-cycPEG-lipo).

CARM1-mediated OGT arginine methylation promotes non-small cell lung cancer glycolysis by stabilizing OGT.

O-GlcNAcylation catalyzed by O-GlcNAc transferase (OGT) plays an important role in the regulation of tumor glycolysis. However, the mechanism underlying OGT regulation remains largely unknown. Here, we showed that coactivator associated arginine methyltransferase 1 (CARM1) sensed changes of extracellular glucose levels in non-small cell lung cancer (NSCLC) cells.

A Three-Tiered Golf Anode towards Ultralong-Life Zn-Mn Aqueous Batteries.

Zn-Mn aqueous batteries (ZMABs) are widely recognized as a promising candidate for large-scale energy storage due to their cost-effectiveness, high safety and environmental friendliness. However, the practical application of ZMABs is hindered by inherent electrical contact loss, hydrogen evolution and dendrite growth on traditional anodes. Here, a three-tiered golf anode with high conductivity is developed to simultaneously enhance the reversibility of Zn and Mn metals.

The influence of COVID-19 pandemic on college students' academic performance and the construction of a learning ability warning system.

Objective: This study explored the impact of prevention and control measures taken by Chinese universities on college students' academic performance during the COVID-19 pandemic.

Participants: The sample includes 1,009 senior students, 1,140 junior and sophomore students, and 1,198 freshman students studying at a top university in China from 2012 to 2023.

Methods: Analysis of variance was used to analyze historical data, and a learning ability warning system based on probabilistic neural networks was further proposed.

On hyper-parameter selection for guaranteed convergence of RMSProp.

RMSProp is one of the most popular stochastic optimization algorithms in deep learning applications. However, recent work has pointed out that this method may not converge to the optimal solution even in simple convex settings. To this end, we propose a time-varying version of RMSProp to fix the non-convergence issues.

Interface Storage Mechanism in Aqueous Ammonium-Ion Supercapacitors with Keggin-Type Polyoxometalates-Modified Ag-BTC.

Ammonium-ion supercapacitors (AISCs) offer considerable potential for future development owing to their low cost, high safety, environmental sustainability, and efficient electrochemical energy storage capabilities. The rapid and efficient charge-transfer process at the AISC can endow them with high capacitive and cycling stabilities. However, the prolonged intercalation/deintercalation of NH in layered and framework materials often results in the cleavage of the active sites and the deconstruction of the framework, which makes it difficult to achieve long-term stable energy storage while maintaining high capacitance in the electrode materials.

An interpretable RNA foundation model for exploring functional RNA motifs in plants.

The complex 'language' of plant RNA encodes a vast array of biological regulatory elements that orchestrate crucial aspects of plant growth, development and adaptation to environmental stresses. Recent advancements in foundation models (FMs) have demonstrated their unprecedented potential to decipher complex 'language' in biology. In this study, we introduced PlantRNA-FM, a high-performance and interpretable RNA FM specifically designed for plants.

Genome-wide analysis and identification of nuclear factor Y gene family in switchgrass (Panicum virgatum L.).

NF-Y is a class of heterotrimeric transcription factor composed of three subunits; NF-YA, NF-YB, and NF-YC. This complex binds to the CCAAT box found in eukaryotic promoters and is involved in the plant development and proliferation at various stages. Although many studies were conducted on NF-Y gene family in various species, but no study has been reported yet in switchgrass (Panicum virgatum L.

Enhanced photocatalytic performance and a mechanistic study of novel black phosphorus/graphene/TiO composite membrane for o-chlorophenol removal.

The heterogeneous catalysis of the composite membrane not only exerts the synergistic effect of different materials but also enable the recyclable use of catalysts, making it an ideal and sustainable strategy for removing pollutants in water. In this study, a novel black phosphorus/graphene/titanium dioxide (BP/GR/TiO) membrane was successfully prepared through the sol-gel method. The composite membrane not only overcame the instability of black phosphorus and the rapid recombination of e/h pairs in titanium dioxide but also synergized with GR to produce a new reactive oxygen species (ROS), singlet oxygen (O), with a longer lifetime and migration distance.

Nitrogen addition accelerates aboveground biomass sequestration in old-growth forests by stimulating ectomycorrhizal tree growth.

Examining whether nitrogen (N) enrichment promotes secondary tree growth in both young (YF) and old-growth forests (OF) is crucial. This will help determine how N addition influences plant carbon sequestration across successional phases in temperate forests. We conducted an eight-year N addition experiment (0, 25, 50, 75 kg N ha yr) in YF and OF in northeast China to investigate the effects of enhanced in situ N deposition on tree growth.

Cue modality modulates interaction between exogenous spatial attention and audiovisual integration.

Exogenous spatial attention attenuates audiovisual integration (AVI). Previous studies on the effects of exogenous spatial attention on AVI have focused on the inhibition of return (IOR) effect induced by visual cues and the facilitation effect induced by auditory cues, but the differences between the effects of exogenous spatial attention (induced by visual and auditory cues) on AVI remain unclear. The present study used the exogenous spatial cue-target paradigm and manipulated cue stimulus modality (visual cue, auditory cue) in two experiments (Experiment 1: facilitation effect; Experiment 2: IOR effect) to examine the effects of exogenous spatial attention (evoked by cues in different modalities) on AVI.

Knock-knee diagnosis in Chinese adolescents: Expert evaluation and defensive strategies in image analysis - A population study.

Background: Knock-knee, a prevalent postural deformity problem among adolescents, poses significant challenges to traditional diagnostic methods in terms of complexity, high cost, and radiation risk. Therefore, there is a demand for diagnostic techniques that are more accessible, safe, and non-invasive for knock-knee.

Methods: We collected 1519 clear whole-body images from 1689 Chinese adolescents aged 10-19 years as image data, and obtained expert annotations on the presence or absence of knock-knee from three orthopedic surgeons.

Equal-Bilayer MoSe Grown by a Nucleation-Etching Strategy with High Carrier Mobility.

Bilayer transition metal chalcogenides (TMDs) have gradually attracted a great deal of attention due to the higher density of states and carrier mobility than monolayer TMDs. Controlling the uniformity of the layer number is very crucial because it will intensively influence the physical properties. However, it is difficult to synthesize equal-bilayer (EB) TMDs with two identical layers via a normal layer-by-layer strategy.

The complete mitochondrial genome of (Diptera: Hippoboscoidea: Streblidae) provides new insights into phylogenetic relationships of Hippoboscoidea.

The family Streblidae is a significant grouping of dipteran insects within the superfamily Hippoboscoidea, which parasitizes the body surface of bats. With the global spread of bat-related pathogens in recent years, Streblidae has gained increasing attention due to its potential for pathogen transmission. A sample of was sequenced on the were obtained, compared with available Streblidae mitogenomes, and the phylogeny of Hippoboscoidea was reconstructed.

A Novel Cellulose-Supported Polymer Electrolyte with High Ionic Conductivity for Lithium Metal Batteries.

The traditional liquid electrolytes pose safety hazards primarily attributed to the flammability of organic solvent, whereas solid-state electrolytes can significantly enhance the safety of lithium-ion batteries. Polymer solid electrolytes are being considered as an effective solution due to their excellent flexibility and low cost, but they suffer low ionic conductivity or high interface impedance. Here, the ketone-containing allyl acetoacetate monomers were polymerized within the cellulose membrane via UV photopolymerization to prepare a cellulose-supported poly-allyl acetoacetate polymer electrolyte.

Adaptive Strategy of the Perennial Halophyte Grass to Long-Term Salinity Stress.

Salinity stress influences plants throughout their entire life cycle. However, little is known about the response of plants to long-term salinity stress (LSS). In this study, , a perennial halophyte grass, was exposed to 300 mM NaCl for two years (completely randomized experiment design with three biological replicates).

, a Small Family of ABA Up-Regulated EAR Motif-Containing Proteins Regulate ABA Responses in Arabidopsis.

The abscisic acid (ABA) signaling pathway is crucial for regulating downstream ABA-responsive genes, which influence plant responses to ABA and abiotic stresses. However, many ABA-responsive genes remain poorly characterized. This study reports on the identification and characterization of ABA up-regulated EAR motif-containing proteins (), a novel family of EAR motif-containing proteins in .

Triftosylhydrazone in Single-Atom Skeletal Editing.

ConspectusIn the past decade, single-atom skeletal editing, which involves the precise insertion, deletion, or exchange of single atoms in the core skeleton of a molecule, has emerged as a promising synthetic strategy for the rapid construction or diversification of complex molecules without laborious synthetic processes. Among them, carbene-initiated skeletal editing is particularly appealing due to the ready availability and diverse reactivities of carbene species. The initial endeavors to modify the core skeleton of heteroarenes through carbon-atom insertion could date back to 1881, when Ciamician and Denstedt described the conversion of pyrroles to pyridines by trapping haloform-derived free carbene.

Effects of multilevel metacognition on group performance and regulation in collaborative learning.

Group metacognition is essential for effective collaboration. However, existing research mainly focuses on individual metacognition in collaborative learning, and some studies focused on interpersonal metacognition. The understanding of group metacognition is limited.

Effects of multiple temperature variations on nitrogen removal and microbial community structure in tidal flow constructed wetlands.

Tidal-flow constructed wetlands (TFCWs) provide distinct advantages for nitrogen removal by enhancing microbial activity through dynamic water level fluctuations. However, effects of temperature on nitrogen transformation processes and microbial community dynamics in TFCWs remain unclear. We analyzed the effects of TFCWs on nitrogen transformation and microbial community structure under different temperature conditions (23, 16, 12, and 8 °C) through 140 days of temperature-controlled experiments.

A stand-alone and point-of-care electrochemical immuno-device for Salmonella typhimurium testing.

The rapid development of accurate and point-of-care diagnostic tools for foodborne diseases has made a massive impact in global health. Salmonella typhimurium (S. typhimurium) exemplifies an enteric pathogen, being a gram-negative bacteria responsible for several gastrointestinal and systemic illnesses.

The benefits of physical literacy for human flourishing: A machine learning-based exploration of adolescents.

Physical literacy is a multidimensional concept considered fundamental for lifelong participation in physical activity. Although theories on the relationship between physical literacy and human flourishing have been proposed, no comprehensive study of this relationship in adolescents has been found. This study aimed to predict human flourishing variables (physical activity, physical health, mental health, and academic performance) that correlate highly with adolescents' physical literacy.

Ethnic disparities of poor households by a multilevel analysis of household and contextual effects: Evidence from a multi-ethnic county of China.

Poverty in multi-ethnic regions has always been a concern due to its complex factors and persistent nature. Using a sample of 8,482 ethnic majority-headed households and 2,011 ethnic minority-headed households distributed in 200 villages of Wangqing County, China, this study uses hierarchical linear models to examine the factors of income at the household level, the ethnic disparities of the household-level effect, and the contextual effect on household-level outcomes. The findings suggest that, in comparison to the majority group, there exists a smaller income gap between male-headed and female-headed poor households within the minority group.