839 results match your criteria: "Northampton General Hospital[Affiliation]"

Although mixing and matching components is a common, safe, and well-documented practice in hip revision surgery, our extensive search indicates that it has not been previously reported for shoulder arthroplasty. This case report presents the use of mixed implants in shoulder revision surgery to reduce morbidity and address flaws in the initial implant design. We describe a case of a patient with multiple epiphyseal dysplasia who was treated for osteoarthritis in his left shoulder with an anatomic shoulder replacement in 2014.

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Miller-Fisher syndrome (MFS) is characterized by the three major components of ophthalmoplegia, ataxia, and areflexia. The occurrence of MFS is relatively uncommon because of its monophasic nature, while recurrent Guillain-Barré syndrome (GBS) is a well-known condition. The pharyngeal-cervical-brachial (PCB) variant is a scarce variant of GBS (3%), which presents with muscle weakness initially involving the neck, oropharynx, and upper extremities.

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Osteoarthritis (OA) is a prevalent degenerative joint disease that significantly impacts mobility and quality of life (QoL). Exercise interventions, including aerobic training, resistance exercises, and multimodal programs, are widely recommended for managing symptoms. This systematic review and meta-analysis aimed to evaluate the effectiveness of various exercise interventions on pain, physical function, and QoL in individuals with knee and hip OA.

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Objectives: We sought to review studies that examine healthcare professionals' and students' knowledge, attitudes and practices (KAP) regarding medication disposal. We also explore recommendations and barriers related to appropriate medication disposal.

Design: A systematic review was conducted that adhered to Preferred Reporting Items for Systematic Reviews and Meta-Analyses.

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  • Traumatic brain injury (TBI) is a serious health issue worldwide, leading to high rates of death and long-term disability, prompting exploration into treatments like tranexamic acid (TXA) for potential benefits.
  • This systematic review analyzed data from 12 randomized controlled trials (RCTs) with nearly 37,500 patients, focusing on TXA's effects on overall mortality and complications like DVT and stroke in TBI patients.
  • Results showed that TXA significantly reduced total mortality compared to placebo without increasing risks for thromboembolic events, and there were no significant differences in the need for neurosurgery or other major complications.
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Cerebral air embolism (CAE) is a rare but life-threatening condition often associated with trauma, such as chest and skull injuries, which allow air to enter the venous system, as well as medical procedures and surgical interventions. It can occur during the insertion of peripheral cannulas or central midline catheters, following lung biopsy procedures, or during vascular surgeries, particularly those involving the head and neck region. CAE can also develop during the removal of central venous cannulas, as air may enter the bloodstream in the process.

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Aim The aim is to compare the incidence of urethral strictures and other complications following monopolar and bipolar transurethral resection of the prostate (TURP). Method We conducted a retrospective study to compare patients who underwent bipolar TURP with those who underwent monopolar TURP between 2017 and 2023. The collected data included demographics, age, history of urethral stricture, prostate size, operation duration, and postoperative complications, such as blood transfusion, transurethral resection (TUR) syndrome, and other relevant data points.

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Background Falls among elderly adults are one of the most common reasons that could lead to injury and modality, as vision is one of the modifiable risk factors for falls. By assessing it, we can detect those needing further follow-up with opticians or ophthalmologists, lowering the risk of falls secondary to poor vision. Methods Data were collected and reviewed retrospectively from a consecutive list of patients who presented with a fall or head injury to the Accident and Emergency Department at Northampton General Hospital.

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  • - Primary ovarian carcinoid tumors are extremely rare, accounting for less than 0.1% of ovarian cancers, and often present with symptoms like abdominal pain and bloating.
  • - A 54-year-old woman experienced dyspnea and edema, which were initially misdiagnosed as heart failure without classic carcinoid syndrome symptoms, but further tests indicated carcinoid disease.
  • - Surgical treatment included valve repair and removal of reproductive organs, underscoring the importance of prompt diagnosis and intervention for managing complications like carcinoid heart disease.
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: Evisceration and incisional hernia (IH) represent a significant morbidity following open or laparoscopic colorectal surgery where midline laparotomy or extraction incision (EI) are performed. We executed a systematic review to evaluate primary mesh closure of laparotomy or EI in colorectal resections of benign or malignant conditions. : A comprehensive literature search was performed using PubMed, Science Direct, Cochrane, and Google Scholar databases for studies comparing prophylactic mesh to traditional suture techniques in closing laparotomy in open approach or EI when minimally invasive surgery was adopted in colorectal procedures, regardless of the diagnosis.

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This literature review critically examines the historical, current, and prospective dimensions of sternal wound reconstruction in the specific context of deep sternal wound infection (DSWI), aiming to enhance patient outcomes and optimise surgical techniques. Preventive measures, including prophylactic antibiotic administration and surgical site preparation, are crucial in reducing the incidence of DSWI. Effective management necessitates a multidisciplinary approach encompassing surgical debridement, drainage, and sternum repair utilising diverse procedures in conjunction with antibiotic therapy.

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Skin problems are common, affecting up to one-third of the population during their lifetime, and they are frequently encountered by advanced clinical practitioners (ACPs) in both primary and secondary care settings. Despite the prevalence of dermatological presentations, ACPs often feel unprepared to conduct a thorough dermatological history and examination. This article aims to provide guidance to trainees and qualified ACPs, whether in acute hospital settings or primary care, to perform dermatological assessments and examinations systematically.

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  • Lower limb oedema is a common issue that can result from benign causes like prolonged sitting or indicate serious health problems such as heart or kidney failure.
  • This clinical review aims to improve the knowledge of practitioners on how to evaluate and manage lower limb oedema, focusing on lymphoedema which can be either primary (genetic) or secondary (acquired).
  • Effective management includes addressing the root causes, appropriate skin care, exercises, compression garments, and possibly referral to a specialist for patient education and improved outcomes.
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  • A 60-something male patient experienced worsening symptoms like confusion, paranoia, cognitive decline, and myoclonus, all while having a history of paranoid schizophrenia.
  • Extensive medical tests, including blood work and brain scans (MRI), did not provide clear answers but showed abnormal brain activity and damage in specific areas.
  • An electroencephalogram (EEG) revealed abnormal sharp wave discharges, indicating the patient was likely in a state of status epilepticus, a severe epileptic condition.
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Chorea is a hyperkinetic movement disorder characterised by involuntary, brief, random and irregular contractions. Acquired chorea can present acutely or subacutely and may be asymmetrical or unilateral. A detailed history and examination are crucial to identify triggering factors and underlying cause.

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  • Laparoscopic sleeve gastrectomy (LSG) is a common weight-loss surgery, and this study examines the value of routinely sending removed stomach tissue for histopathological analysis over a five-year period.
  • The research involved a retrospective analysis of 203 patients, mostly female, to assess their demographics, preoperative procedures, and histopathological results, revealing that 81.3% had normal gastric mucosa and only a small fraction had clinically significant findings.
  • The study concludes that since most specimens showed non-significant results and no patients required further treatment, the routine practice of histopathological examination after LSG may need reevaluation.
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Background: Locally advanced cervical cancer is treated with chemoradiotherapy (standard of care), but many patients still relapse and die from metastatic disease. We investigated chemoradiotherapy with or without induction chemotherapy to determine whether induction chemotherapy improves both progression-free survival and overall survival.

Methods: The INTERLACE trial was a multicentre, randomised phase 3 trial done at 32 medical centres in Brazil, India, Italy, Mexico, and the UK.

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  • - Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycaemic state (HHS) are urgent diabetic emergencies that need quick detection and treatment.
  • - Advanced clinical practitioners (ACPs) are vital for diagnosing, initiating treatment, and coordinating care, although some may lack confidence dealing with these complications.
  • - The review covers the causes, risk factors, and management strategies for DKA and HHS, emphasizing the need to reduce risks and prevent future occurrences for better patient outcomes.
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  • Iron deficiency anaemia often shows various symptoms, including pica, which is the craving for non-food items.
  • The case study discusses a Caucasian woman in her forties who had a two-year habit of eating excessive amounts of cherry tomatoes, leading to rare symptoms like yellowish skin discoloration.
  • Diagnosis revealed iron deficiency anaemia and carotenemia, and her health improved significantly with a blood transfusion and treatment using ferric carboxymaltose (ferinject).
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This intriguing case report explores an interesting complication following percutaneous cholecystostomy for the management of acute cholecystitis in an elderly female with multiple comorbidities. Despite initial improvement, she later presented with recurrent symptoms, due to a collection of gallstones, that had migrated through the cholecystostomy tract, requiring exploration, stone retrieval and abscess drainage. While percutaneous cholecystostomy remains an effective treatment for managing acute cholecystitis in high-risk surgical candidates, this case highlights the rare yet critical risk of extrahepatic gallstones and abscess formation.

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Background: Medical students receive relatively little exposure to intensive care medicine throughout their undergraduate training. The COVID-19 pandemic further hindered students' exposure with the entrance to intensive care units (ICU) limited. To address the problem, this study explored the use of assisted reality technology to create a smart classroom in intensive care.

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