14 results match your criteria: "NorthShore University Healthcare System[Affiliation]"
Am J Sports Med
January 2024
Northshore University Healthcare System, Evanston, Illinois, USA.
Orthobiologics are rapidly growing in use given their potential to augment healing for multiple musculoskeletal conditions. Orthobiologics consist of a variety of treatments including platelet-rich plasma and stem cells that provide conceptual appeal in providing local delivery of growth factors and inflammation modulation. The lack of standardization in nomenclature and applications within the literature has led to a paucity of high-quality evidence to support their frequent use.
View Article and Find Full Text PDFMed Anthropol
November 2022
Department of Obstetrics and Gynecology, NorthShore University Healthcare System, Evanston, Illinois, USA.
The publication of A Randomized Trial of Induction Versus Expectant Management (ARRIVE), conducted in the United States in 2018, heralded a paradigm shift within the obstetrical management of term pregnancy among people who have not previously given birth. ARRIVE finds its home among other canonical - and controversial - randomized controlled trials (RCTs) within obstetrics. We argue that RCTs have their own (after)life, both creating new subjects for biomedical intervention and recalibrating who reproductive health practitioners consider to be at risk of adverse health outcomes.
View Article and Find Full Text PDFUrogynecology (Phila)
October 2022
Center for Restorative Pelvic Medicine, Department of Obstetrics and Gynecology, Houston Methodist Hospital, Houston, TX.
Importance: Comparing one-year surgical outcomes of two widely used surgical procedures for apical suspension.
Objectives: The objective of this study is to compare anatomic outcomes after minimally invasive sacrocolpopexy (MISC) and vaginal uterosacral ligament suspension (vUSLS).
Study Design: This was a multicenter, retrospective cohort study through the Fellows' Pelvic Research Network.
Minerva Anestesiol
July 2019
Department of Neurosurgery, NorthShore University Healthcare System, Evanston, IL, USA -
J Vasc Surg Venous Lymphat Disord
January 2019
University of Michigan, Ann Arbor, Mich.
Guideline 1.1: Compression after thermal ablation or stripping of the saphenous veins. When possible, we suggest compression (elastic stockings or wraps) should be used after surgical or thermal procedures to eliminate varicose veins.
View Article and Find Full Text PDFArthritis Rheumatol
February 2017
Biomedical Research Centre of Aragon, University of Zaragoza, Fundación Aragon I+D, and Nanoscience Institute of Aragon, Zaragoza, Spain.
Objective: Granzyme A (GzmA) levels are elevated in the plasma and synovium of patients with rheumatoid arthritis (RA), suggesting involvement of this protease in the pathogenesis of the disease. GzmA contributes to sepsis by regulating the production of proinflammatory cytokines. The purpose of this study was to evaluate the contribution of GzmA to the pathogenesis of RA in vivo and to examine the possibility that GzmA acting via tumor necrosis factor (TNF) stimulates osteoclastogenesis.
View Article and Find Full Text PDFKnee
January 2016
Departments of Orthopaedic Surgery, Northwestern University, Chicago, IL, USA; Rehabilitation Institute of Chicago, Chicago, IL, USA; Department of Orthopaedic Surgery, Northshore University Healthcare System, Evanston, IL, USA; Departments of Physical Medicine and Rehabilitation, Northwestern University, Chicago, IL, USA; Departments of Biomedical Engineering, Northwestern University, Chicago, IL, USA. Electronic address:
Introduction: Anterior cruciate ligament injuries are closely associated with excessive loading and motion about the off axes of the knee, i.e. tibial rotation and knee varus/valgus.
View Article and Find Full Text PDFBJU Int
December 2014
Division of Urology, NorthShore University Healthcare System, Evanston, IL, USA.
Objective: To evaluate whether genetic correction using the genetic variants prostate-specific antigen (PSA)-single nucleotide polymorphisms (SNPs) could reduce potentially unnecessary and/or delayed biopsies in African-American men.
Subjects And Methods: We compared the genotypes of four PSA-SNPs between 964 Caucasian and 363 African-American men without known prostate cancer (PCa). We adjusted the PSA values based on an individual's PSA-SNP carrier status, and calculated the percentage of men that would meet commonly used PSA thresholds for biopsy (≥ 2.
J Urol
June 2014
Department of Urology and Population Health, New York University and Manhattan Veterans Affairs, New York, New York. Electronic address:
Purpose: Genome-wide association studies have identified an increasing number of single nucleotide polymorphisms associated with prostate cancer risk. Some of these genetic variants are also associated with serum prostate specific antigen levels and lower urinary tract symptoms, raising the question of whether they are truly prostate cancer biomarkers or simply lead to detection bias. Therefore, we determined whether single nucleotide polymorphisms associated with prostate cancer risk are more strongly associated with tumor or prostate volume.
View Article and Find Full Text PDFJ Pain Symptom Manage
April 2014
Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Context: Symptom cluster research expands cancer investigations beyond a focus on individual symptoms in isolation.
Objectives: We conducted a prospective longitudinal study of sleep, fatigue, depression, anxiety, and perceived cognitive impairment in patients with breast cancer undergoing chemotherapy.
Methods: Patient-reported outcome measures were administered prior to chemotherapy, at Cycle 4 Day 1, and six months after initiating chemotherapy.
J Urol
May 2013
Division of Urology, Northshore University Healthcare System, Evanston, Illinois, USA.
Purpose: Recent studies have identified genetic variants associated with increased serum prostate specific antigen concentrations and prostate cancer risk, raising the possibility of diagnostic bias. By correcting for the effects of these variants on prostate specific antigen, it may be possible to create a personalized prostate specific antigen cutoff to more accurately identify individuals for whom biopsy is recommended. Therefore, we determined how many men would continue to meet common biopsy criteria after genetic correction of their measured prostate specific antigen concentrations.
View Article and Find Full Text PDFInt J Oncol
February 2011
Department of Medicine, Northshore University Healthcare System, Evanston, IL 60201, USA.
Polyethylene glycol (PEG) is a safe and effective chemopreventive agent against colorectal carcinogenesis in cell culture, animal models and human subjects. Although the precise molecular mechanism is unclear, we previously reported that PEG suppresses colonic epithelial proliferation. As cellular proliferation is driven by complex G1-S phase transition, we now characterize the role of PEG on cell cycle regulation.
View Article and Find Full Text PDFAm J Surg
May 2011
Department of Surgery, NorthShore University Healthcare System, Skokie Hospital, Skokie, IL 60076, USA.
Background: Core needle biopsy (CNB) is used increasingly not only to diagnose breast cancer, but to determine tumor histology, grade and marker expression, select neoadjuvant therapy, and predict sentinel lymph node status. Thus, we undertook this study to evaluate the accuracy of CNB as a predictor of breast cancer histology and marker expression.
Methods: We identified 209 Breast Cancer Registry cases with a preoperative CNB and reviewed all clinicopathologic data for accuracy.
Eur Spine J
May 2010
Department of Orthopaedic Surgery, NorthShore University Healthcare System, 1000 Central Street, Suite 880, Evanston, IL 60201, USA.
Lateral mass screws have a history of successful clinical use, but cannot always be used in the subaxial cervical spine. Despite safety concerns, cervical pedicle screws have been proposed as an alternative. Pedicle screws have been shown to be biomechanically stronger than lateral mass screws.
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