1,251 results match your criteria: "NorthShore University Health-System[Affiliation]"

Introduction: Proactive esophageal cooling reduces injury during radiofrequency (RF) ablation of the left atrium (LA) for the treatment of atrial fibrillation (AF). New catheters are capable of higher wattage settings up to 90 W (very high-power short duration, vHPSD) for 4s. Varying power and duration however does not eliminate the risk of thermal injury.

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Background: Hernia repairs are one of the most common general surgery procedures and an essential part of training for general surgery residents. The widespread incorporation of robotic hernia repairs warrants the development of a procedure-specific robotic curriculum to assist novice surgeons in improving technical skills.

Objective: To evaluate a robotic hernia simulation-based curriculum for general surgery residents using video review.

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Systematic treatment and management of postpartum hypertension using remote patient monitoring.

Pregnancy Hypertens

December 2024

Section of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Chicago Medicine, IL, United States. Electronic address:

Objective: To describe postpartum visit attendance and postpartum blood pressure control among patients enrolled in a remote patient monitoring program and compare these outcomes by race.

Study Design: A prospective cohort study of postpartum patients with a diagnosis of hypertensive disorders of pregnancy at the University of Chicago between October 2021 and April 2022. All patients received remote patient monitoring as routine care but consented separately for the use of their data.

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Tight Phosphate Control in ESKD Patients is Warranted: PRO.

Kidney360

December 2024

Division of Nephrology and Hypertension, NorthShore University Health System-Endeavor Health, University of Chicago, Pritzker School of Medicine, Evanston, Illinois.

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In-stent restenosis.

J Cardiovasc Surg (Torino)

October 2024

Department of Surgery, Advocate Lutheran General Hospital, Park Ridge, IL, USA.

Endovascular arterial recanalization has become the mainstay therapy for peripheral arterial occlusive disease. Although immediate technical success is achieved in greater than 90% of cases, longer-term results continue to vary based on the clinical presentation, and the treated target lesion. In the current era, sustained patency can be expected following intervention in the carotid, coronary, renal, and iliac arteries.

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Pain serves as a vital innate defense mechanism that can significantly impact an individual's quality of life. Understanding the physiological effects of pain well plays an important role in developing novel pain treatments. Nociceptor neurons play a key role in pain and inflammation.

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Purpose Of The Study: Increased risk for adverse birth outcomes, long work hours, limited control over one's own schedule, and concern for making up time may color resident perceptions of their pregnancy during residency. We aimed to survey residents across four different specialties about their personal experiences with pregnancy during training.

Study Design: Using a novel, validated, anonymous web-based survey instrument, we assessed experiences around pregnancy during residency training nation-wide.

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Article Synopsis
  • The study focuses on the impact of tricuspid regurgitation (TR) on heart remodeling, comparing outcomes in patients treated with the TriClip device versus those receiving standard medical therapy in a randomized controlled trial.
  • Researchers utilized advanced imaging techniques, including cardiac magnetic resonance and 4D-CT, to assess heart changes at baseline, 30 days, and one year follow-ups.
  • Results showed that the TriClip significantly reduced TR volume by 70% at 30 days, leading to notable reductions in right ventricular size and area, with these improvements maintained after one year, unlike the control group.
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Background: There are several surgical options each with their potential for complications, differences in length of procedure, and in meaningful outcomes. This study aims to explore those outcomes after Roux-en-Y Gastric Bypass (RYGB) and Loop Duodenal Switch (LDS).

Objective: The purpose of this project is to offer a comparative analysis of RYGB and LDS at the NorthShore University Health System for up to 4 years postoperatively.

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Article Synopsis
  • Molecular studies indicate that ALT is a crucial prognostic marker for shorter relapse-free survival (RFS) in pancreatic neuroendocrine tumors (PanNETs) and other neoplasms.
  • The development of a new chromogenic ALT assay (ALT-CISH) was initiated to address clinical limitations of the traditional fluorescence in situ hybridization (FISH) method, showing a 100% agreement with FISH results in validating that ALT is present in 31% of primary PanNETs.
  • The study demonstrated that ALT status is significantly associated with poorer RFS in both PanNET and leiomyosarcoma (LMS) patients, with ALT being an independent prognostic factor
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Article Synopsis
  • Researchers aimed to create and validate a prediction score for futile recanalization (FR) in patients with low Alberta Stroke Program Early Computed Tomography Scores (ASPECTS) who underwent endovascular thrombectomy (EVT) for large vessel occlusions (LVO).
  • The study analyzed data from 219 patients with anterior circulation LVO and identified key predictors of FR, resulting in the development of the SNAP score, which considers factors like the site of occlusion and patient age.
  • The SNAP score successfully predicted FR with an area under the curve of 0.79 in both training and validation cohorts, indicating its potential usefulness for guiding expectations in patients undergoing EVT for severe strokes.
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Objective: Shared decision-making (SDM) between parents facing extremely preterm delivery and the medical team is recommended to develop the best course of action for neonatal care. We aimed to describe the creation and testing of a literature-based checklist to assess SDM practices for consultation with parents facing extremely preterm delivery.

Study Design: The checklist of SDM counseling behaviors was created after literature review and with expert consensus.

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Background: Osteochondral defects (OCDs) in the knee joint have significant clinical implications, particularly regarding contact pressures and pressure distribution. Understanding how these factors are influenced by defect size and location is crucial for developing effective therapeutic strategies.

Purpose/hypothesis: The purpose of this study was to investigate the impact of defect size and location on contact pressures and pressure distribution in the knee joint.

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Article Synopsis
  • Biologics and small-molecule therapies have improved the treatment landscape for atopic dermatitis, but older systemic treatments are still in use.
  • The PEDIatric STudy in Atopic Dermatitis is a 10-year observational study tracking the effectiveness and safety of dupilumab, cyclosporine, and methotrexate in children under 12 with moderate-to-severe atopic dermatitis, with interim results available after 2 years.
  • Results show that dupilumab led to better improvements in skin severity, itching, and fewer discontinuations or adverse effects compared to methotrexate and cyclosporine.
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Aims: Men with lower urinary tract symptoms (LUTS) represent a heterogeneous group, and treatment decisions are often based on severity of symptoms and physical examination findings. Identification of clinically meaningful subtypes could allow for more personalized care. This study advances phenotyping efforts from the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) by adding data domains to previous phenotyping using urologic symptoms alone.

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Article Synopsis
  • The study investigates the characteristics of coronary artery disease in young adults (≤35 years) compared to older adults (>60 years) who experienced ST-segment elevation myocardial infarction (STEMI).
  • Using optical coherence tomography (OCT), researchers found that plaque erosion was more prevalent in younger patients, while plaque rupture was more common in older patients.
  • The study concluded that the mechanisms behind STEMI differ based on age, with young individuals showing more cases of subacute thrombus linked to plaque erosion.
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Background: Patients with malignant melanoma have an increased risk of developing secondary hematologic malignancy, and patients with hematologic malignancies have an increased risk of developing melanoma. Rarely, sentinel lymph node biopsies (SLNBs) collected for melanoma staging might harbor lymphoma or even carcinoma, which may represent a second primary malignancy (SPM). Biopsied lymph node(s) might serve as the first site of recognition for a SPM.

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Survival outcomes after omission of surgery for ductal carcinoma in situ.

NPJ Breast Cancer

September 2024

Department of Breast Surgical Oncology, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.

Clinical trials of active surveillance (AS) for Ductal Carcinoma in Situ (DCIS) are underway. We sought to understand the historical management of biologically favorable DCIS and to determine the outcomes of patients who did not have immediate surgery. Using data from the NCDB from 2004 to 2017, the selected cohort included women >40 years of age, with low or intermediate grade and hormone receptor (HR) positive DCIS.

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Background And Objectives: This study aimed to compare outcomes of low Alberta Stroke Program Early Computed Tomography Score (ASPECTS) patients with stroke who underwent mechanical thrombectomy (MT) within 6 hours or 6 to 24 hours after stroke onset.

Methods: A retrospective cohort study was conducted using data from a large multicenter international registry from 2013 to 2023. Patients with low ASPECTS (2-5) who underwent MT for anterior circulation intracranial large vessel occlusion were included.

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Background: Black men consistently have higher rates of prostate cancer (PCA)- related mortality. Advances in PCA treatment, screening, and hereditary cancer assessment center around germline testing (GT). Of concern is the significant under-engagement of Black males in PCA GT, limiting the benefit of precision therapy and tailored cancer screening despite longstanding awareness of these disparities.

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Open surgical repair of abdominal aortic aneurysm (AAA) is often regarded as a near-permanent operation with little long-term complications. Reported herein is a case of delayed rupture of an enlarging AAA sac after open repair requiring re-exploration in a patient presenting with flank pain and ipsilateral hydronephrosis. The natural history of a large, excluded aneurysm sac after open AAA repair, hypothesized etiology for this rare occurrence, and proposed diagnostic and therapeutic algorithm are described.

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