32 results match your criteria: "North-Eastern Hill University (NEHU)[Affiliation]"

Using the solid-state reaction technique, varied YSiO phosphors activated by europium (Eu) ions at varied concentrations were made at calcination temperatures of 1000 °C and 1250 °C during sintering in an air environment. The XRD technique identified the monoclinic structure, and the FTIR technique was used to analyze the generated phosphors. Photoluminescence emission and excitation patterns were measured using varying concentrations of Eu ions.

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In this study, an alginate-chitosan (AL-CS) nanocomplex decorated with vitamin C coated iron oxide nanoparticles (FeO-vit C NPs) was investigated as a novel nanoiron fortification agent. The FeO-vit C NPs decorated on AL-CS nanocomplex underwent comprehensive characterization, including zeta potential, fourier transform infrared spectroscopy, X-ray diffraction, and UV-vis spectroscopy. The transmission electron microscopy (TEM) analysis confirmed the decoration of FeO-vit C NPs on AL-CS nanocomplex.

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Rapid urban growth in an unplanned way, decreased forest cover and consequential changes in land use in urban and rural areas have become pivotal obstacles for policymakers and urban planners to a great extent. Specifically, in a developing country like India, the repercussions of these changes have generated a substantial alteration in climate in the form of increased land surface temperature (LST), heat islands and associated human health risks. This research was initiated to assess the interrelationship between LST and LULC dynamics using spatial techniques over the Barasat Sub-Division in West Bengal (India).

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Panoramic view of artificial fruit ripening agents sensing technologies and the exigency of developing smart, rapid, and portable detection devices: A review.

Adv Colloid Interface Sci

September 2024

NanoBio High-Tech Materials Research Center, Department of Biological Sciences and Bioengineering, Inha University, Incheon 22212, Republic of Korea. Electronic address:

Recently, the availability of point-of-care sensor systems has led to the rapid development of smart and portable devices for the detection of hazardous analytes. The rapid flow of artificially ripened fruits into the market is associated with an elevated risk to human life, agriculture, and the ecosystem due to the use of artificial fruit ripening agents (AFRAs). Accordingly, there is a need for the development of "Point-of-care Sensors" to detect AFRAs due to several advantages, such as simple operation, promising detection mechanism, higher selectivity and sensitivity, compact, and portable.

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Millets are gaining attention as a superfood due to their higher nutritional value and cost-effectiveness. In this regard, extraction condition for the development of finger millet-based beverage was optimized using a central composite design. Soaking time (X) and temperature (X) in the range of 5-10 h and 40-60°C, respectively, were the independent variables taken for three responses, namely, yield, total solids, and sedimentation index.

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Goat milk gels (GMGs) are popular food due to their high water content, low-calorie density, appealing taste, texture enhancers, stability, and satiety-enhancing characteristics, making them ideal for achieving food security and zero hunger. The GMGs were optimized using the central composite design matrix of response surface methodology using goat milk powder (35-55 g), whole milk powder (10-25 g), and potato powder (10-15 g) as independent variables. In contrast, complex modulus, flow stress, and forward extrudability were chosen as dependent variables.

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Iron deficiency is a significant cause of iron deficiency anemia (IDA). Treatment of IDA is challenging due to several challenges, including low target bioavailability, low palatability, poor pharmacokinetics, and extended therapeutic regimes. Nanotechnology holds the promise of revolutionizing the management and treatment of IDA.

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The solid-state reaction method was utilised to create a down-conversion phosphor in an air environment in CaYO:Eu nanocrystalline material. The calcination temperature was set at 1000 °C, and the sintering temperature was set at 1300 °C. Following annealing, confirmation of the crystallinity quality of the phosphor was accomplished by the use of X-ray diffraction analysis.

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Article Synopsis
  • - The study focuses on developing and evaluating a LAMP PCR test to diagnose human brucellosis, which is a significant public health issue, especially in low-resource settings where traditional PCR is costly and complex.
  • - The researchers tested the LAMP PCR’s sensitivity and specificity using both cultured samples and clinical samples, finding it could detect brucella DNA quickly, with results showing 90.91% sensitivity and 99.37% specificity.
  • - The LAMP PCR test demonstrated high accuracy in detecting brucellosis in patients, and it’s suggested to be a practical point-of-care option for diagnosing the disease in areas where conventional methods are not feasible.
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Ethnobotany, botany, phytochemistry and ethnopharmacology of the genus Thalictrum L. (Ranunculaceae): A review.

J Ethnopharmacol

April 2023

Angiosperm Taxonomy Laboratory, Department of Botany, Shivaji University, Kolhapur 416 004, Maharashtra, India.

Ethnopharmacological Relevance: Thalictrum (Ranunculaceae) is known for its important alkaloids which have been reported to exhibit various pharmacological activities, viz. antitumor, antimicrobial, antitussive, antiamebic, hypotensive effects, HIV antiviral, etc. Throughout the world, the plant has been used as a tonic, purgative, stimulant, aperient and is utilized in various systems of medicine in the treatment of various ailments like snake bite, jaundice, rheumatism, stomachache, wounds, swellings, uterine tumors, paralysis, joints pain, nervous disorders, toothache, diarrhea, piles, fever, peptic ulcer, ophthalmic, headache, diuretic, dyspepsia, convalescence, etc.

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Stomach cancer is the fifth most common cancer in terms of prevalence and incidence and the fourth leading cause of mortality in men and women worldwide. It is well-established that aberrant DNA methylation in cells can lead to carcinogenesis. The primary objective of our study was to investigate the aberrant DNA methylation status of genes associated with stomach cancer with a particular reference to the ethnic population of Mizoram, North East India.

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Cyanidin-3-glucoside (C3Ghv) compounds were purified and isolated from the anthocyanins extract of C3Ghv were studied for antioxidant and cytoprotective properties on pancreatic β-cells of rat insulinoma cells (RINm5F) against the oxidative stress induced by streptozotocin (STZ). The exposure of RINm5F cells to C3Ghv at concentration of 100 and 200 μg/mL for 24 h reduced 10% and 23% cell viability, respectively, as compared to control cells. The pre-treatment of RINm5F cells with C3Ghv (50 µg/mL) increased the cell viability by 29% as compared to control, on being treated with STZ (10 mM) for 24 h.

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In this study, we have analyzed how geo-ecological cues for endangered Olive Ridley turtles' mass nesting behavior got modified by impact of four severe cyclones during 2010-2019 that made landfall in the vicinity of Rushikulya estuary, which is one of the largest mass nesting congregation (arribada) sites in the world. Analyzing last 10 years of shoreline dynamics, we show that even the slightest modification in beach morphology influenced their nesting behavior in Rushikulya rookery. Shoreline change analysis showed periodic phases of high/low erosion and the northward longshore sediment movement, which becomes impeded by the southern spit, the length of which increased by about 1800 m.

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This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal).

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Article Synopsis
  • - Oropharyngeal cancer, common in Meghalaya, India, is linked to unique risks like smokeless tobacco and areca nut consumption, but its underlying genetic changes are not well understood.
  • - This study analyzed DNA methylation and gene expression in oropharyngeal cancer patients, finding 194 silenced and 241 overexpressed genes, with key pathways related to immune responses and osteoclast differentiation significantly involved.
  • - The research showed differences in DNA methylation and gene expression compared to other head and neck cancers, and no HPV DNA was found in the tumor samples, enhancing the understanding of oropharyngeal cancer.
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The aims of this study are to evaluate phytochemical composition, antimicrobial and antioxidant activities of different solvent-assisted blood fruit pulp extracts. The extracts of blood fruit were prepared with various solvents namely, water, ethyl acetate, methanol and acetone. These extracts were divided into two groups, first group of extract were thermosonicated (treated) and the second group were not exposed to thermosonication (untreated).

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Blood fruit () has important bioactive compounds, antioxidant properties and some essential minerals, which plays an essential part in human nutrition and traditional medicine for treating arthritis, jaundice, hypertension, cancer, etc. This work was conducted to optimize the parameters of spray drying process for production of blood fruit juice powder and its quality was compared with freeze dried and tray dried powder. It was observed that powder produced by spray drying techniques resulted in higher yield, solubility and better retention of resveratrol content and was considered to be of superior quality, having a higher degree of reconstitution ratio as compared to powders produced by freeze and tray drying techniques.

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Assessment of environmental impact of coal mining on natural ecosystems and monitoring of subsequent ecological restoration process of mined areas are essential for devising reclamation strategies for mining-affected landscapes. The present study was designed to assess the post-disturbance recovery of vegetation, primary productivity and soil nutrient build-up of a humid subtropical grassland ecosystem following coal mining activities. Two replicate sites each for the undisturbed grasslands (UG), mining-affected (MG) and recovering grasslands of 15 (RG15) and 50 (RG50) years old were selected.

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This study reports enhanced efficacy of encapsulated α-Terpineol to control fungal, aflatoxin B (AFB) and free radicals mediated deterioration of stored maize samples. The α-Terpineol loaded chitosan nanoemulsion (α-TCsNe) was characterized through SEM, FTIR and XRD techniques. The α-TCsNe exhibited enhanced antifungal activity against aflatoxin secreting strain of Aspergillus flavus (AF-LHP-S1) and 12 other food borne moulds as well as AFB production at 0.

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Bafilomycin-A1 and ML9 Exert Different Lysosomal Actions to Induce Cell Death.

Curr Mol Pharmacol

July 2020

Advanced Center for Chronic Disease (ACCDiS), Facultad de Ciencias Químicas y Farmacéuticas & Facultad de Medicina, Universidad de Chile, Santiago, Chile.

Objective: Bafilomycin-A1 and ML9 are lysosomotropic agents, irrespective of cell types. However, the mechanisms of lysosome targeting either bafilomycin-A1 or ML9 are unclear.

Methods: The present research has been carried out by different molecular and biochemical analyses like western blot, confocal imaging and FACS studies, as well as molecular docking.

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Article Synopsis
  • - Oral Squamous Cell Carcinoma (OSCC) is a common and aggressive type of cancer, and the study focuses on how DNA methylation, an epigenetic factor, is involved in its development, particularly in the ethnic population of Meghalaya, North East India.
  • - Researchers identified over 27,000 specific DNA sites that showed different methylation patterns in oral cancer tissues compared to normal tissues, with 45 genes in the promoter region being particularly noteworthy.
  • - Among these genes, 38 were hypermethylated (more methylation than normal), and 7 were hypomethylated (less methylation), with some genes overlapping with previous studies, suggesting potential new biomarkers for diagnosing OSCC.
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Objective: Juvenile myoclonic epilepsy (JME) is the most common form of idiopathic generalized epilepsies (IGEs) and is genetically heterogeneous. Mutations in cause JME. Because about 2 million people in India are affected by JME alone, we investigated the prevalence of mutations in the gene in the Indian population with JME.

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The orchid species Dendrobium nobile belonging to the family Orchidaceae and genus Dendrobium (a vast genus that encompasses nearly 1,200 species) has an herbal medicinal history of about 2000 years in east and south Asian countries. Here, we report the complete chloroplast genome sequence of D. nobile from northeastern India for the first time.

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