2 results match your criteria: "North Shore-LIJ Comprehensive Epilepsy Centers[Affiliation]"

Few studies have examined the issues that are specific to the older person with epilepsy, a population of increasing prominence in epilepsy management. Our understanding of the impact of epilepsy in the older person is based predominantly on what is inferred from studies of younger adults. Consequently, there is relatively little documented about the impact of epilepsy on the everyday lives of older people.

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Effect of lamotrigine on depressive symptoms in adult patients with epilepsy.

Epilepsy Behav

February 2007

North Shore-LIJ Comprehensive Epilepsy Centers, Long Island Jewish Medical Center, EEG Lab, 270-05 76th Avenue, New Hyde Park, NY, USA.

In this investigation, the effects of lamotrigine versus placebo on depressive symptoms in patients with epilepsy were prospectively assessed. This investigation was a secondary analysis of a randomized, double-blind, placebo-controlled, parallel-group study in which adult patients received adjunctive lamotrigine (n=32) or placebo (n=38) for a 7-week dose escalation phase, followed by a 12-week maintenance phase, for primary generalized tonic-clonic (PGTC) seizures. Mood symptoms were assessed with the Beck Depression Inventory, second edition (BDI-II), the Profile of Mood States (POMS), and the Cornell Dysthymia Rating Scale-Self-Report (CDRS).

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