Discovery of the cicada genus Becquartina Kato, 1940 (Hemiptera: Cicadidae: Cicadinae) in India with the description of a new species from Meghalaya.

The genus Becquartina Kato, 1940 (Hemiptera: Cicadidae) is reported for the first time from India with a new species, Becquartina bicolor sp. nov., along with records of two distinct colour forms, from the northeastern Indian state of Meghalaya and located within the Indo-Burma Biodiversity hotspot.

On the elephant trails: habitat suitability and connectivity for Asian elephants in eastern Indian landscape.

Identifying suitable habitats and conserving corridors are crucial to the long-term conservation of large and conflict-prone animals. Being a flagship species, survival of Asian elephants is threatened by human-induced mortality and habitat modification. We aimed to assess the habitat suitability and connectivity of the Asian elephant Linnaeus, 1758 habitat in the state of Odisha in eastern India.

Green synthesis of N,S-doped carbon dots for tartrazine detection and their antibacterial activities.

A simple, green and low-cost method was developed for the synthesis of highly fluorescent N,S-doped carbon dots (N,S-CDs) the hydrothermal treatment of Gandha Prasarini (GP) leaves as a natural source of carbon, nitrogen and sulfur. The as-prepared N,S-CDs exhibited excitation-dependent green fluorescence emission ( = 450 nm, = 525 nm) with excellent stability, and were used as a fluorescent probe for the selective detection of tartrazine with a limit of detection of 0.18 μM.

Relation of ACE2 with co-morbidity factors in SARS-CoV-2 pathogenicity.

In the last 3 years of the pandemic situation, SARS-CoV-2 caused a significant number of deaths. Infection rates for symptomatic and asymptomatic patients are higher than that for death. Eventually, researchers explored that the major deaths are attributed to several comorbidity factors.

Ce-catalyzed regioselective synthesis of pyrazoles from 1,2-diols tandem oxidation and C-C/C-N bond formation.

A novel and efficient cerium-catalyzed tandem oxidation and intermolecular ring cyclization of vicinal diols with hydrazones has been achieved for the regioselective synthesis of pyrazole derivatives. The corresponding 1,3-di- and 1,3,5-trisubstituted pyrazoles were obtained in moderate to excellent yields. The reaction has the advantages of mild conditions, easily available starting materials, broad substrate scope and good functional group tolerance.

Harnessing the Role of Bacterial Plasma Membrane Modifications for the Development of Sustainable Membranotropic Phytotherapeutics.

Membrane-targeted molecules such as cationic antimicrobial peptides (CAMPs) are amongst the most advanced group of antibiotics used against drug-resistant bacteria due to their conserved and accessible targets. However, multi-drug-resistant bacteria alter their plasma membrane (PM) lipids, such as lipopolysaccharides (LPS) and phospholipids (PLs), to evade membrane-targeted antibiotics. Investigations reveal that in addition to LPS, the varying composition and spatiotemporal organization of PLs in the bacterial PM are currently being explored as novel drug targets.

Evaluation of antimicrobial, anticancer potential and Flippase induced leakage in model membrane of Centella asiatica fabricated MgONPs.

The use of chemically synthesized nanoparticles and crude plant extracts as antimicrobial -anticancer agents have many limitations. In this study, we have used Centella asiatica extract (CaE) having relatively less explored but tremendous medicinal properties, as reducing and stabilizing agents to green synthesize magnesium oxide nanoparticles (MgONPs) using magnesium nitrate. In comparison to the bulk material, capabilities of Ca-MgONPs as an improved antibacterial, antifungal, and anticancer agent in human prostatic carcinoma cells (PC3), as well as membranolytic capability in model cell membrane, were studied.

Sour beer production in India using a coculture of Saccharomyces pastorianus and Lactobacillus plantarum: optimization, microbiological, and biochemical profiling.

The study's objective was to develop a co-fermentation process with appropriate fermentation parameters to produce a sour beer (similar to a Belgium sour beer) with an ethanol content of 6-8% (v/v) using a coculture of Saccharomyces pastorianus and Lactobacillus plantarum. Statistical optimization was conducted to determine fermentation conditions to produce a sour beer with ~ 3 mg/mL of lactic acid, similar to the traditional sour beer levels. Studies were conducted on the microbial dynamics and volatile compounds produced during this fermentation and aging process.

Lipid Flip-Flop-Inducing Antimicrobial Phytochemicals from are Bacterial Membrane Permeability Enhancers.

An amphiphilic phytochemical fraction isolated from methanol extract of leaf powder contained six terpenoids, two flavonoids, and one alkaloid that induced rapid flip-flop of fluorescent phospholipid analog in the phosphatidyl choline bilayer. Lipid-flipping activity of the methanol-extracted fraction of (MEFGS) was dose-dependent and time-dependent with a rate constant = (12.09 ± 0.

Utility of Fine Needle Aspiration Cytology (FNAC) in the diagnosis of tuberculous lymphadenitis compared to GeneXpert in a tertiary health care center in Northern Odisha, India.

Background: Diagnosis of extrapulmonary tuberculosis including tuberculous lymphadenitis (TBLN) is challenging because of its atypical clinical presentation, paucibacillary nature of mycobacteria at the infected sites, variation in sensitivity of a test to specimens collected by different methods and from different infected tissues.

Methods: In the present study, suspected individuals for lymph node tuberculosis irrespective of age were enrolled prospectively and specimens were collected aseptically by fine needle aspiration (FNA). After the implementation of exclusion criteria, FNA specimens from a total of 278 cases of suspected TBLN were evaluated for cytomorphology (FNAC), presence of acid-fast bacillus (AFB) in smear microscopy and specific detection of mycobacterial DNA in cartridge-based nucleic acid amplification test (CBNAAT).

Shifting of cell cycle arrest from the S-phase to G2/M phase and downregulation of EGFR expression by phytochemical combinations in HeLa cervical cancer cells.

Cervical cancer is a major human papillomavirus-related disease and is the fourth leading cause of death by cancer among women. Plants are an important source of anticancer compounds and many of them are currently used in the treatment of cancer. Several reports suggest the efficacy of plant-derived compounds increases when used in combination.

On the neutrosophic soft set with rough set theory.

Rough set is a very powerful invention to the whole world for dealing with uncertain, incomplete and imprecise problems. Also soft set theory and neutrosophic set theory are advance mathematical tools to handle these uncertain, incomplete, inconsistent information in a better way. The purpose of this article is to expand the scope of rough set, soft set and neutrosophic set theory.

Effect of parenteral endotoxin administration on the immuno-haematological responses of catfish.

Endotoxin, the outer cell wall membrane lipopolysaccharide component of the Gram-negative bacteria is a factor responsible for a number of complications/disorders and plays important role in the associated with pathophysiological complications and pathogenesis of many diseases in animals. Unlike higher animals which are extremely sensitive to endotoxin, fish are found to be resistant to endotoxic shock and earlier studies though limited have demonstrated the patho-physiological, immuno-endocrinological and immuno-neurological effects of LPS/endotoxin in aquatic animals including fish. Herein in the present investigation, the effect of pure endotoxin on immuno-haematological parameters of stinging catfish ranging from 50-60 g was studied by intraperitoneally injecting 0.

Intelligent computing on time-series data analysis and prediction of COVID-19 pandemics.

Covid-19 disease caused by novel coronavirus (SARS-CoV-2) is a highly contagious epidemic that originated in Wuhan, Hubei Province of China in late December 2019. World Health Organization (WHO) declared Covid-19 as a pandemic on 12th March 2020. Researchers and policy makers are designing strategies to control the pandemic in order to minimize its impact on human health and economy round the clock.

Development of Submergence-Tolerant, Bacterial Blight-Resistant, and High-Yielding Near Isogenic Lines of Popular Variety, 'Swarna' Through Marker-Assisted Breeding Approach.

The rice variety 'Swarna' is highly popular in the eastern region of India. The farmers of eastern India cultivate mainly rainfed rice and face the adverse effects of climate change very frequently. Rice production in this region is not stable.

Non-homologous dsODN increases the mutagenic effects of CRISPR-Cas9 to disrupt oncogene E7 in HPV positive cells.

Genome editing tools targeting high-risk human papillomavirus (HPV) oncogene could be a promising therapeutic strategy for the treatment of HPV-related cervical cancer. We aimed to improve the editing efficiency and detect off-target effects concurrently for the clinical translation strategy by using CRISPR-Cas9 system co-transfected with 34nt non-homologous double-stranded oligodeoxynucleotide (dsODN). We firstly tested this strategy on targeting the Green Fluorescent Protein (GFP) gene, of which the expression is easily observed.

In vivo immunostimulatory effect of the amoebocyte lysate and plasma of Asian horseshoe crab, in a piscine model.

Antimicrobial proteins/peptides are becoming a new generation of immunostimulants for prevention and disease control in human and animals, including aquatic animals. As the haemolymph of horseshoe crabs ( contains broad ranges of bioactive compounds, we have explored the in vivo immunostimulating potential of amoebocyte lysate and plasma using a fish model. Indian major carp, yearlings were injected intraperitoneally with two doses of lysate and plasma at 50 and 100 µg protein per fish.

Description of three new species of the genus Mata Distant, 1906 (Hemiptera: Cicadidae: Cicadinae: Oncotympanini) with notes on their natural history from Indian state of Meghalaya, India.

Three new species of the Asian genus Mata Distant, 1906 (Hemiptera: Cicadidae) viz. Mata lenonia sp.nov.

Optimization of xylanase from Pseudomonas mohnii isolated from Simlipal Biosphere Reserve, Odisha, using response surface methodology.

Background: Xylanase has long been recognized as a widely used industrially important enzyme. There are some bacterial species already reported to produce xylanase which have potent xylanolytic activity towards the use of this enzyme in the production of bioethanol from lignocellulosic biomass. In this view, an efficient xylanolytic bacterial strain was isolated and screened from the soil sample of Simlipal Biosphere Reserve.

Recent Advances in Nanotechnology: A Novel Therapeutic System for the Treatment of Alzheimer's Disease.

A amyloid-β (Aβ) plaque formation in the brain is known to be the root cause of Alzheimer's disease (AD), which affects the behavior, memory, and cognitive ability in humans. The brain starts undergoing changes several years before the actual appearance of the symptoms. Nanotechnology could prove to be an alternative strategy for treating the disease effectively.

Emerging Molecular Prospective of SARS-CoV-2: Feasible Nanotechnology Based Detection and Inhibition.

The rapid dissemination of SARS-CoV-2 demonstrates how vulnerable it can make communities and is why it has attained the status of global pandemic. According to the estimation from Worldometer, the SARS-CoV-2 affected cases and deaths are exponentially increasing worldwide, marking the mortality rate as ∼3.8% with no probability of its cessation till now.