Muscle gap approach under a minimally invasive channel technique for treating long segmental lumbar spinal stenosis: A retrospective study.

This study aimed to compare the efficacy of muscle gap approach under a minimally invasive channel surgical technique with the traditional median approach.In the Orthopedics Department of Traditional Chinese and Western Medicine Hospital, Tongzhou District, Beijing, 68 cases of lumbar spinal canal stenosis underwent surgery using the muscle gap approach under a minimally invasive channel technique and a median approach between September 2013 and February 2016. Both approaches adopted lumbar spinal canal decompression, intervertebral disk removal, cage implantation, and pedicle screw fixation.

Treatment of fingertip degloving injury using the bilaterally innervated sensory cross-finger flap.

Treatment of a fingertip degloving injury continues to be a challenge problem. This article reports repair of this type of injury using a modified cross-finger flap, including both dorsal branches of the digital nerves. From December 2007 to March 2010, the flap was used in 17 digits of 17 patients who had a fingertip degloving injury.

Direct and reversed dorsal digito-metacarpal flaps: a review of 24 cases.

Background And Aim: The common source for reconstruction of soft tissue defects of the fingers is either the same finger or the adjacent finger. However, when the donor areas are damaged by concomitant injuries, these options are not available. The purpose of this study was to report on reconstruction of these complex digital injuries using the dorsal digito-metacarpal flaps (DDMFs) and to evaluate the efficacy of this technique.

Reconstruction of a soft tissue defect in the finger using the heterodigital neurocutaneous island flap.

Background: This article describes reconstruction of a soft tissue defect in the finger using the heterodigital neurocutaneous island flap and reports the results of the use of the flap.

Methods: From February of 2008 to March of 2011, the neurocutaneous island flap was used in 12 patients with soft tissue defects in the middle phalanx or the proximal interphalangeal joint, or both. The injured fingers included 4 index, 3 middle, 3 ring and 2 little fingers.

Repair of multiple finger defects using the dorsal homodigital island flaps.

Background: Providing soft-tissue coverage for multiple finger defects remains a challenge for the hand surgeons. This article reports reconstruction of multiple digital defects using the dorsal homodigital island flaps based on the dorsal branch of the digital artery.

Methods: Over 3 years, a retrospective study was conducted with 12 patients who had multiple finger defects treated with the dorsal homodigital island flaps.

Treatment of soft-tissue loss with nerve defect in the finger using the boomerang nerve flap.

Background: This study reports simultaneous repair of soft-tissue loss and proper digital nerve defect in the finger using a boomerang nerve flap including nerve graft from the dorsal branch of the proper digital nerve.

Methods: From July of 2007 to May of 2010, the flap was used in 17 fingers in 17 patients. The injured fingers included five index, seven long, and five ring fingers.

Use of the dorsal digital sensate free flap for reconstruction of volar soft tissue defect of digits.

Sensate cross-finger flaps and homodigital and heterodigital island flaps can usually be used for sensory reconstruction in the volar aspect of the digit. However, when the donor areas are damaged by concomitant injuries, these flaps are not available. The free dorsal digital flap, including both dorsal branches of the proper digital nerves, can be used as an alternative to resolve this problem.

Reconstruction of proper digital nerve defects in the thumb using a pedicle nerve graft.

Background: Traumatic defects of the proper digital nerve in the thumb affect tactile perception of the thumb pulp. This article reports on the treatment of the defect using a pedicle nerve graft taken from the dorsal branch of the proper digital nerve of the index or long finger, or both.

Methods: From May of 2006 to March of 2010, the pedicle nerve graft was used in 16 thumbs in 16 patients.

Sensory reconstruction of a finger pulp defect using a dorsal homodigital island flap.

Background: This article reports sensory reconstruction of a finger pulp defect using a dorsal homodigital island flap including double dorsal branches of the proper digital nerves.

Methods: From February of 2008 to December of 2009, the dorsal homodigital island flap was used in 15 fingers in 15 patients. The average patient age was 32 years.

Alterations of serum biomarkers associated with lung ventilation function impairment in coal workers: a cross-sectional study.

Background: Previous studies have demonstrated that alterations in certain circulating biomarkers may be correlated with Coal workers' pneumoconiosis (CWP). This study investigated the relationship between changes of serum biomarkers and pulmonary function during the development of CWP.

Methods: Lung function parameters and specific serum indices were measured in 69 non-smoking coal workers, including 34 miners with CWP, 24 asymptomatic miners and 11 miners with minimal symptoms.

[Morphological study on commonly-used acupoints for thyroid surgery under acupuncture anesthesia].

Objective: To study the morphologic structure, afferent projections of "Neiguan" (PC6), "Hegu" (LI 4) and "Futu" (LI 18) acupoint regions so as to understand their underlying mechanisms in acupuncture anesthesia for thyroid surgery.

Methods: A total of 66 Wistar rats were used in the present study. (1) Horseradish peroxidase (HRP, 10%, 10 microL) was injected into PC 6, LI 4 and LI 18 acupoints and the thyroid area on the right side, respectively (n = 6).

[Effect of alendronate on interleukin-1beta induced chondrocytes of rat in vitro].

Objective: To investigate the feasibility of alendronate (ALN) in treating osteoarthritis (OA) by observing the effects of ALN on interleukin 1beta (IL-1beta) induced chondrocytes of rat in vitro.

Methods: The chondrocytes of knee articular surface from 15 SD rats (1-month-old, female or male, weighing 100-150 g) were cultured. The chondrocytes were observed by inverted phase contrast microscope and identified by toluidine blue staining and HE staining.

[Repair of acute avulsion-type achilles tendon rupture by locking-loop stereoscopic suture].

Objective: To summarize the clinical application and experience of repairing acute avulsion-type achilles tendon rupture by locking-loop stereoscopic suture.

Methods: Between January 2006 and June 2010, 41 cases of acute avulsion-type achilles tendon rupture were treated by locking-loop stereoscopic suture. Among 41 patients, 33 were male and 8 were female with an average age of 41 years (range, 18-56 years); the locations were left side in 27 cases and right side in 14 cases.

[Effects of taurine on hemorheology of rats with type 2 diabetes].

Objective: To observe the effects of taurine on hemorheology and oxidative stress of diabetic rats.

Methods: 40 rats were divided into control group, diabetes group and treatment group at random. Diabetic model was reproduced by intraperitoneal injection of streptozotocin.

Enhancement of subchondral bone quality by alendronate administration for the reduction of cartilage degeneration in the early phase of experimental osteoarthritis.

To evaluate the effects of alendronate (ALN) on the subchondral bone quality and cartilage degeneration in the early phase of experimental model of osteoarthritis after anterior cruciate ligament transaction (ACLT). Thirty male adult healthy Japanese white rabbits after right ACLT or sham operation were divided into three groups (n = 10 per group): Sham; ACLT + ALN [after ACLT, the rabbits were treated with ALN daily starting from 4 days after surgery (10 μg/kg/d subcutaneously)]; and ACLT + NS group (after ACLT, the rabbits were injected saline as a placebo). At 60 days postsurgery, specimens from the affected knees were harvested.

[Effect of p38MAPK on proliferation in human embryonic lung fibroblasts in vitro].

Objective: To study the proliferation effect of the AM supernatant incubated activation of p38 mitogen activated protein kinases (p38MAPK) signal transduction pathway in human embryonic lung fibroblasts, and to participate in the development of fibrosis in silicosis.

Methods: The silicotic alveolar macrophages were collected by bronchoalveolar lavage and incubated in vitro in the DMEM medium containing SiO₂ (50 µg/ml) and DMEM medium without SiO₂ for 18 h. Then the AM supernatant incubated for 18 h was collected.

[Study on preparation and quality standard of Xueshuantong Drop Pills].

Objective: To optimize the best technical parameters and establish the quality standard for Xueshuantong Drop Pills.

Methods: Using moulding probability of drop pill as the evaluation to choose the best dropping condition. Using parallel experimentation for the choice of proportion of drug and matrix, and refrigerant; HPLC method was employed on ODS column which was used with a mobile phase of acetontrile-water, 0 min 20% A, 14 min 40% A, 15 min 60% A, 16 min 20% A.

[The distribution and influential factors of serum high sensitivity C-reactive protein in general population].

Objective: To observe the distribution and influence factors of serum high sensitivity C-reactive protein (hs-CRP) in general population.

Methods: In a cross-sectional population survey, a total of 101 510 subjects who were employed by Kailuan Group had been carried out a healthy examination in the period of 2006 to 2007. In the statistical analysis, we observed 91 123 subjects (males 72 805, females 18 318) who had full information and met the inclusion criteria of the study.

Distribution and differentiation of marrow stem cells transplanted by different ways in ischemic myocardium and other organs in rabbits.

In our study, BrdU-labeled marrow stem cells (MSCs) were directly (group 1), by the coronary artery (group 2), or by the ear vein (group 3) transplanted into myocardium to observe their distribution and differentiation in acute myocardial infarction (AMI) rabbit models. BrdU-positive cells, and BrdU and α-sarcomeric actin double positive cells were visible in the infarcted zones and its peripheral region. Cell processes between BrdU-positive cells and between BrdU-positive cells and host cardiomyocytes linked together.

[The protective effects of ischemic preconditioning on the kidney injury following with ischemia/reperfusion of limbs and the possible mechanisms].

Aim: To explore the protective effects of ischemic preconditioning on the kidney injury following with ischemia/reperfusion (I/R) of limbs.

Methods: The models of I/R injury of limbs were constructed in rabbits. The blood from right external jugular vein, renal artery and renal vein represent the peripheral blood, into and out-flowing kidney blood (IKB, OKB) respectively.

[Effect of ERK1/2 signal pathway on the proliferation of lung fibroblast activated by SiO₂].

Objective: To observe the effect of ERK1/2 signal pathway activated by SiO₂ in the proliferation of human embryonic lung fibroblast mediated by silicotic alveolar macrophages.

Method: The alveolar macrophages (AM) harvested from silicotic sufferers by bronchoalveolar lavage (BAL) were interacted with SiO₂ suspension once more. HELF, pretreated with the inhibitor PD98059 (50 µmol/L) for 1 hour, were stimulated by conditional supernatant fluid of silicotic sufferers.

[Relationship between urinary 1-hydroxypyrene level and peripheral blood lymphocyte chromosomal damage among coke oven workers].

Objective: To investigate the relationship between the urinary 1-hydroxypyrene level and cytokinesis-block micronucleus in peripheral blood lymphocyte in coke oven workers.

Methods: One hundred and fifty-eight workers from a coke plant and 158 referents without occupational PAHs exposure were recruited in this study. Urnary level of 1-hydroxypyrene was measured by alkaline hydrolysis combined with high performance liquid chromatography as an internal exposure dose, and the chromosomal damage of peripheral blood lymphocyte were evaluated with cytokinesis-block micronucleus (CBMN) method.

[The risk predictive value of high sensitivity C-reactive protein level for new hemorrhagic stroke events].

Objective: To study the risk prediction for new intracerebral hemorrhage (ICH) with high sensitivity C-reactive protein (hs-CRP) level.

Methods: In a retrospective, nested, case-controlled study, 323 cases of ICH were identified and matched with 646 controls. The hs-CRP levels at baseline were compared between the two groups.

[Effectiveness of low molecular weight heparin for prevention of deep vein thrombosis after total hip arthroplasty].

Objective: To investigate the pathogenesis of deep vein thrombosis (DVT) after total hip arthroplasty (THA) and the preventive effectiveness of low molecular weight heparin (LMWH).

Methods: The occurrence condition of DVT in 90 cases undergoing THA treated with LMWH between February 2003 and March 2004 was retrospectively analyzed. Among 90 cases, 39 were treated with LMWH at a dose of 5000 U/day (high dose group) and 51 at a dose of 2500 U/day (low dose group).