7,586 results match your criteria: "North Carolina Agriculture & Technical State University[Affiliation]"

Article Synopsis
  • The review focuses on identifying the characteristics and roles of milk coproducts (like milk oligosaccharides) from human, bovine, and porcine sources, particularly how they affect the gut health and immunity of young pigs.
  • Early weaning (at 3-4 weeks) in modern pig production leads to intestinal challenges in piglets, such as dysbiosis and pathogen colonization, which compromise their health.
  • Milk oligosaccharides serve as prebiotics, supporting beneficial gut bacteria, preventing harmful pathogens from adhering to gut cells, and enhancing immune responses, making them crucial for the development of suckling and nursery pigs.
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While an abundance of evidence exists regarding infectious outcomes in children as they relate to the short-term benefits of breastfeeding, there is limited evidence related to similar impacts beyond one year and after breastfeeding has stopped. Specifically, little is known about the long-term benefits of breastfeeding for acute health outcomes after infancy, particularly in Nigeria. The Nigeria Demographic and Health Survey data was used in this study.

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  • 53 isolates of Aspergillus section Nidulantes fungi were studied, revealing that 30 clinical isolates, including four from COVID-19 patients, were misidentified as the cryptic pathogen A. latus, which resulted from a hybridization event.
  • The research showed that A. latus displays significant genetic diversity and that both parental subgenomes are actively expressed in clinical isolates, responding to different environmental conditions.
  • Key differences in drug resistance and growth in oxidative stress were found between A. latus hybrids and related species, along with four features that could help in accurately identifying A. latus in the future.
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This study examines the impact of Bisphenol A (BPA), a prevalent environmental estrogenic toxicant, on the ovarian development of mice. Mice were exposed to varying BPA doses from in utero to postnatal stages, up to weaning (day 21, PND 21) and puberty (day 45, PND 45). The BPA content in the serum of the offspring mice on PND 45 was higher than that of the mice sacrificed at PND 21.

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  • The heterotrimeric glucose dehydrogenase (BcGDH) from Burkholderia cepacia has a unique ability to directly transfer electrons to electrodes but struggles with activity towards both glucose and galactose.
  • To improve its substrate specificity, researchers used the crystal structure of BcGDH's subunits to perform site-directed mutagenesis, targeting specific residues that affect its performance.
  • The newly engineered mutant, α-G322Q-N474S-N475S, demonstrated over a 2-fold increase in glucose activity while significantly reducing galactose activity, achieving much greater specificity for glucose compared to the wild type enzyme.
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Objective: To evaluate clinical and microbial outcomes in dogs with untreated subclinical bacteriuria (SB) through longitudinal follow-up.

Methods: Between February 24, 2022, and July 7, 2023, healthy client-owned dogs ≥ 4 years old with no evidence of lower urinary tract signs (LUTS) were recruited for a longitudinal, prospective study. Phase 1 dogs with SB were followed for 28 days to document comorbidities and microbiological findings (ie, urinalysis, urine culture, and fimH gene in Escherichia coli isolates).

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Safeguarding the SDG promise to end hunger and leave no one behind: the plight of children in the Gaza Strip.

Lancet Glob Health

November 2024

Department of Nutrition and Food Sciences, Faculty of Agricultural and Food Sciences, American University of Beirut, Beirut 11072020, Lebanon; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina Chapel Hill, North Carolina 27599, USA.

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Sweetpotato, Ipomoea batatas (L.) Lam. (2n = 6x = 90), is among the world's most important food crops and is North Carolina's most important vegetable crop.

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We explored how the ratio of blood-feeding behaviour-nonfeeding, bird feeding (ornithophily) and mammal feeding (mammalophily)-and voltinism (univoltine and multivoltine) vary over a latitudinal gradient from Alaska to Florida. These two fixed species traits were divided into five mutually exclusive combinations of trait states-nonfeeding/univoltine, ornithophilic/univoltine, mammalophilic/univoltine, ornithophilic/multivoltine and mammalophilic/multivoltine-within each of three datasets (north, east and west). We found a significant association between location (north, east and west) and trait state, which was driven by the large percentage of nonfeeding females in the north.

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  • A new study highlights the importance of considering natural hive conditions in research about honey bee microbiota, rather than relying solely on artificial lab settings.
  • The research reveals that the transition in behavior from nurse bees to forager bees can significantly influence physiological and behavioral outcomes in bee studies, potentially confounding results related to microbial treatments.
  • This work emphasizes the need for interdisciplinary collaboration and careful experimental design to accurately understand the complex interactions between hosts and their microbiota.
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The SARS-CoV-2 pandemic has challenged more scientists to detect viruses and to visualize virus-containing spots for diagnosis and infection control; however, detection principles of commercially available technologies are not optimal for visualization. Here, a convenient and universal homogeneous detection platform named proximity-unlocked luminescence by sequential enzymatic reactions from antibody and antibody/aptamer (PULSERAA) is developed. This is designed so that the signal appears only when the donor and acceptor are in proximity on the viral surface.

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Introduction: Limited evidence exists on the relationship between ultra-processed food (UPF) consumption and overweight/obesity amongst young children. This study aimed to assess UPF consumption, its socioeconomic correlates and its association with overweight/obesity amongst under-five children in Lebanon.

Materials And Methods: Data pertinent to children aged 6 months to 4.

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Article Synopsis
  • Distantly related organisms, like cactophilic yeasts, can evolve similar traits and lifestyles to survive in comparable environments, with this study analyzing over 1,000 yeast species to understand their convergent evolution.
  • Researchers found that cactophily (association with cacti) evolved independently about 17 times and could be predicted with 76% accuracy using genomic and phenotypic data, with thermotolerance being the most significant factor.
  • The study also revealed horizontal gene transfer and duplications in genes related to plant cell wall degradation, indicating that these adaptive traits arose from different molecular pathways, and highlighted a potential link between cactophilic lifestyles and yeast becoming human pathogens.
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Diterpenoids from Isodon serra with promising anti-MRSA activities.

Int Microbiol

September 2024

Laboratory for Functional Foods and Human Health, Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, Kannapolis, NC, 28081, USA.

A series of known diterpenoids from Isodon serra (Maxim.) Hara exhibited antibacterial activities against Staphylococcus aureus and even methicillin-resistant S. aureus (MRSA).

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Article Synopsis
  • - The study explored how substituting soybean meal with rocket seed cake at different levels (0%, 25%, 50%, and 75%) affected the growth and feed efficiency of male lambs over 105 days.
  • - Lambs fed a diet with 25% rocket seed cake (RSC25) showed better feed intake and weight gain compared to those on higher or lower RSC levels, while those on a 75% replacement (RSC75) had the worst performance.
  • - The RSC25 diet also improved economic efficiency, leading to higher overall profitability, confirming that 25% rocket seed cake is an effective substitute for soybean meal in lamb diets.
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Multiple routes to fungicide resistance: Interaction of Cyp51 gene sequences, copy number and expression.

Mol Plant Pathol

September 2024

United States Department of Agriculture-Agricultural Research Service, Department of Entomology and Plant Pathology, North Carolina State University, Raleigh, North Carolina, USA.

We examined the molecular basis of triazole resistance in Blumeria graminis f. sp. tritici (wheat mildew, Bgt), a model organism among powdery mildews.

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We describe experiments that evaluated potential sex pheromone components for 6 North American click beetle species. In field trials in Illinois, South Carolina, North Carolina, and Virginia, male beetles of 6 species were strongly attracted to geranyl butyrate (Agriotes insanus Candèze), 5-methylhexyl (Z)-4-decenoate (Elater abruptus Say), 11-dodecenyl butyrate (Melanotus ignobilis Melsheimer), and limoniic acid (Gambrinus griseus [Palisot de Beauvois], G. rudis [Brown], and G.

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  • Researchers studied strokes from 1990 to 2021 to understand how many people get them and how they are affected around the world.
  • In 2021, strokes caused about 7.3 million deaths and were a major cause of health problems, especially in specific regions like Southeast Asia and Oceania.
  • There are differences in stroke risks based on where people live and their age, and some areas actually saw more strokes happening since 2015.
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Fecal microbial transplants as investigative tools in cancer.

Am J Physiol Gastrointest Liver Physiol

November 2024

Department of Microbiology, Immunology, and Biochemistry, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, United States.

The gut microbiome plays a critical role in the development, progression, and treatment of cancer. As interest in microbiome-immune-cancer interactions expands, the prevalence of fecal microbial transplant (FMT) models has increased proportionally. However, current literature does not provide adequate details or consistent approaches to allow for necessary rigor and experimental reproducibility.

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We examined several American alligators, Alligator mississippiensis (Daudin, 1802) (Crocodilia: Alligatoridae) from Louisiana, Alabama, and South Carolina in August 2022. The intestine of one alligator from Alabama was infected by Dracovermis occidentalis Brooks and Overstreet, 1978 (Platyhelminthes: Digenea: Liolopidae Odhner, 1912), a seldom collected and incompletely described trematode that lacks a representative nucleotide sequence. Liolopidae comprises 5 genera and 15 species: Liolope spp.

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Carotenoids.

Adv Nutr

November 2024

Nutrition and Health Research Group, Department of Precision Health, Luxembourg Institute of Health, Thomas Edison, Strassen, Luxembourg. Electronic address:

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The phosphorus challenge: biotechnology approaches for a sustainable phosphorus system.

Curr Opin Biotechnol

December 2024

School of Sustainable Engineering and the Built Environment, Arizona State University, Tempe, AZ 85259, USA.

Phosphorus (P) is essential for growing crops, but the supply of high-quality phosphate rock reserves used for fertilizer production is finite while losses of P from the food/waste system cause considerable environmental damage. A variety of emerging approaches in biotechnology are reviewed that hold promise for improving the sustainability of P use in the food/water systems. These include improved sensors, cell culture approaches to meat production, bio-based P adsorption and transformation strategies, advancements in understanding of polyphosphate-accumulating organisms, and new approaches involving biomineralization and anaerobic treatment.

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Article Synopsis
  • - The study investigates the genetic basis of the peel stripe margin pattern in watermelons by crossing two distinct lines with different margin appearances, revealing a single recessive gene responsible for the clear pattern.
  • - Genetic mapping techniques identified a specific location on chromosome 6 that contains a MYB transcription factor gene, with two significant mutations linked to the clear stripe pattern.
  • - Further analysis of gene expression and transcriptomic data during key developmental stages suggests that numerous transcription factors and metabolic processes contribute to the differences in peel patterns between the two watermelon lines.
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Yeasts in the subphylum Saccharomycotina are found across the globe in disparate ecosystems. A major aim of yeast research is to understand the diversity and evolution of ecological traits, such as carbon metabolic breadth, insect association, and cactophily. This includes studying aspects of ecological traits like genetic architecture or association with other phenotypic traits.

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Coral reefs support an incredible abundance and diversity of fish species, with reef-associated fisheries providing important sources of income, food, and dietary micronutrients to millions of people across the tropics. However, the rapid degradation of the world's coral reefs and the decline in their biodiversity may limit their capacity to supply nutritious and affordable seafood while meeting conservation goals for sustainability. Here, we conduct a global-scale analysis of how the nutritional quality of reef fish assemblages (nutritional contribution to the recommended daily intake of calcium, iron, and zinc contained in an average 100 g fish on the reef) relates to key environmental, socioeconomic, and ecological conditions, including two key metrics of fish biodiversity.

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