28 results match your criteria: "North Campus Research Center[Affiliation]"

Heterogeneous mechanics of the mouse pulmonary arterial network.

Biomech Model Mechanobiol

October 2016

Department of Molecular and Integrative Physiology, University of Michigan, 2800 Plymouth Road, North Campus Research Center, Ann Arbor, MI, 48109-5622, USA.

Individualized modeling and simulation of blood flow mechanics find applications in both animal research and patient care. Individual animal or patient models for blood vessel mechanics are based on combining measured vascular geometry with a fluid structure model coupling formulations describing dynamics of the fluid and mechanics of the wall. For example, one-dimensional fluid flow modeling requires a constitutive law relating vessel cross-sectional deformation to pressure in the lumen.

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Article Synopsis
  • The study investigates the role of fibroblast growth factor 21 (FGF21) in the metabolic benefits and cancer treatment potential of ketogenic diets (KDs), which have been popular for weight loss and therapy.
  • Researchers conducted experiments with mice on different protein-enriched and protein-depleted KDs to assess the impact of FGF21 on energy balance, glucose regulation, and tumor growth.
  • Results show that increased FGF21 levels during protein starvation don't contribute to maintaining normal blood sugar levels or the energy benefits of KDs, suggesting that the positive effects of KDs are linked to protein malnutrition rather than FGF21.
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The role of community health workers in diabetes: update on current literature.

Curr Diab Rep

April 2013

Robert Wood Johnson Clinical Scholars Program, University of Michigan, North Campus Research Center (NCRC), Ann Arbor, MI 48109, USA.

Community health worker (CHW) interventions have been found to be a promising strategy for improving diabetes outcomes, especially among low-income and racial and ethnic minority populations. This review serves as an update of the literature published since 2011 on CHWs' role in diabetes care. In our review of the most current literature, we noted several key areas of advancement.

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