Psychometric evaluation of the elderly mobility scale in Indonesia.

Background: The Elderly Mobility Scale (EMS) is widely used to identify mobility limitations in older adults, though it has not been validated in Indonesia.

Aim: To evaluate the reliability and validity of the Indonesian version of the EMS (EMS-I).

Method: A cross-sectional design involving 230 older adults in South Tangerang City, Indonesia, was used.

Accelerated risk of renal disease progression in pre-ESRD patients with proton pump inhibitors use: a nationwide population-based study.

Background: Although Proton pump inhibitors (PPIs) were mostly prescribed for gastrointestinal (GI) disease widely, there were numerous studies about PPIs and adverse renal outcome. Most evidence was to evaluate the risk of PPIs in patients with normal renal function and in the absence of the moderate to advanced chronic kidney disease (CKD). This study focuses on the accelerated progression of renal function following proton pump inhibitors (PPIs) use, and the increased risks of acute kidney injury (AKI) among moderate to advanced CKD (pre-ESRD) patients.

Deep learning model for protein multi-label subcellular localization and function prediction based on multi-task collaborative training.

The functional study of proteins is a critical task in modern biology, playing a pivotal role in understanding the mechanisms of pathogenesis, developing new drugs, and discovering novel drug targets. However, existing computational models for subcellular localization face significant challenges, such as reliance on known Gene Ontology (GO) annotation databases or overlooking the relationship between GO annotations and subcellular localization. To address these issues, we propose DeepMTC, an end-to-end deep learning-based multi-task collaborative training model.

Advanced Li-S Battery Configuration Featuring Sulfur-Coated Separator and Interwoven rGO/CNT Fabric Current Collector.

The development of lithium-sulfur batteries (LSBs) marks a crucial milestone in advancing energy storage solutions essential for sustainable energy transitions. With high theoretical specific capacity, cost-effectiveness, and reduced ecological footprint, LSBs promise to enhance electric vehicle ranges, extend portable electronics' operational times, and stabilize grids integrated with renewable energy. However, challenges like complex processing, electrode instability, and poor cycling stability hinder their commercialization.

GeneSPIDER2: large scale GRN simulation and benchmarking with perturbed single-cell data.

Single-cell data is increasingly used for gene regulatory network (GRN) inference, and benchmarks for this have been developed based on simulated data. However, existing single-cell simulators cannot model the effects of gene perturbations. A further challenge lies in generating large-scale GRNs that often struggle with computational and stability issues.

Ordered spatial configuration protects representations of dissimilar items and reduces the similarity effect in visual working memory.

Although similarity could improve visual working memory (VWM) performance, it remains unclear how the spatial configuration of visual information influences the similarity effect in VWM. We explored this question by manipulating the orderliness of spatial configuration (ordered vs. scrambled) in the simultaneous (Experiment 1) and sequential (Experiment 2) change detection tasks.

Investigations on corrosion resistance of steel coated with chromium-free ZTM conversion coating.

Chromium-free conversion coatings based on Zr/Ti/Mo (ZTM) compounds via chemical conversion technology were investigated to improve the corrosion performance of SPCC-JISG 31 steels. A preliminary study was carried out to evaluate the influences of critical parameters, including the concentrations of active species Zr, Ti and Mo, and the conversion bath's pH, on the protective efficiency using a Statistical design of experiments (DoE) methodology. Passivation layer with compositional Mo, Ti and Zr elements has been employed on the steels by dipping in mixed solutions containing 17 g/l NaMoO, 1 g/l KTiF and 7 g/l KZrF under pH = 5.

Sheehan's syndrome presenting with panhypopituitarism and central diabetes insipidus: a case report.

Background: Sheehan's syndrome is a rare condition, which is classically characterized by anterior pituitary hypofunction following postpartum shock or hemorrhage. While diabetes insipidus (DI) is not commonly associated with Sheehan's syndrome, we present a rare case of a multiparous female developing rapid-onset panhypopituitarism and DI following severe postpartum hemorrhage.

Case Presentation: A previously healthy 39-year-old woman, gravida 5, para 4, presented with hypovolemic shock after vaginal delivery, attributed to severe postpartum hemorrhage, necessitating emergent hysterectomy.

The trajectory of smoking cessation after treatment and its related factors in Taiwan.

Smoking has multiple negative effects on health; therefore, the Taiwanese government provides smoking cessation clinics to smokers. This study aimed to explore the trajectory of smoking cessation after smokers received treatment and the variables related to different trajectories. A retrospective longitudinal study was conducted, in which 735 adult smokers who received smoking cessation medications were recruited.

Microplastics in Asian rivers: Geographical distribution, most detected types, and inconsistency in methodologies.

Microplastics pose a significant environmental threat, with potential implications for toxic chemical release, aquatic life endangerment, and human food chain contamination. In Asia, rapid economic growth coupled with inadequate waste management has escalated plastic pollution in rivers, positioning them as focal points for environmental concern. Despite Asia's rivers being considered the most polluted with plastics globally, scholarly attention to microplastics in the region's freshwater environments is a recent development.

APLF facilitates interstrand DNA crosslink repair and replication fork protection to confer cisplatin resistance.

Replication stress converts the stalled forks into reversed forks, which is an important protection mechanism to prevent fork degradation and collapse into poisonous DNA double-strand breaks (DSBs). Paradoxically, the mechanism also acts in cancer cells to contribute to chemoresistance against various DNA-damaging agents. PARP1 binds to and is activated by stalled forks to facilitate fork reversal.

Size-dependent linear and nonlinear optical responses of silicon clusters.

Owing to strong quantum confinement effects and no periodic constraints, the geometric and electronic structures of silicon clusters differ from those of crystalline silicon. Although previous studies have elucidated the optical properties of silicon clusters, some issues remain unresolved. To address these, this study examined the size-dependent linear and nonlinear optical responses of silicon clusters through first-principles calculations.

Association Between Risk of Clostridium difficile Infection and Duration of Proton Pump Inhibitor or H2-Receptor Antagonist Use in Hospitalized Patients.

Introduction: Limited studies have evaluated the association between Clostridium difficile infection (CDI) and the duration of proton pump inhibitor (PPI) or histamine H2-receptor blocker (H2RA) use and provided a cutoff duration for PPI or H2RA use to mitigate a substantially increased risk of CDI. We aimed to evaluate these associations in hospitalized patients using a nationwide insurance claims database.

Methods: We conducted a nested case-control study to identify cases with a first ever record of CDI in a study cohort undergoing PPI or H2RA therapy from the National Health Insurance Database from 2012 to 2018.

Characterization of Fe-Containing and Pb-Containing Nanoparticles Resulting from Corrosion of Plumbing Materials in Tap Water Using a Hyphenated ATM-DMA-spICP-MS System.

Single-particle inductively coupled plasma mass spectrometry (spICP-MS) has been used to characterize metallic nanoparticles (NPs) assuming that all NPs are spherical and composed of pure element. However, environmental NPs generally do not meet these criteria, suggesting that spICP-MS may underestimate their true sizes. This study employed a system hyphenating the atomizer (ATM), differential mobility analyzer (DMA), and spICP-MS to characterize metallic NPs in tap water.

A Linear Two-Coordinate Cr(II) Complex: Synthesis, Characterization, and Reactivity.

The synthesis and characterization of a linear two-coordinate Cr(II) amido complex, Cr{N( Bu)Dipp} (Dipp=2,6-diisopropylphenyl), from the reaction of 1 molar equivalent (equiv) of CrCl and 2 equiv. of LiN( Bu)Dipp is reported. Single-crystal X-ray diffractometry (SC-XRD) analysis revealed that it has a short Cr-N bond distance of 1.

Delaminated MnPS with Multiple Layers Coupled with Si Featuring Ultrahigh Detectivity and Environmental Stability for UV Photodetection.

Silicon (Si), the dominant semiconductor in microelectronics yet lacking optoelectronic functionalities in UV regions, has been researched extensively to make revolutionary changes. In this study, the inherent drawback of Si on optoelectronic functionalities in UV regions is potentially overcome through heterostructure coupling of delaminated p-type MnPS, having bulk, multiple-layer, and few-layer features, with n-type Si. By artificially mimicking the architectures of shrubs with unique UV shading phenomena, the revolutionary multiple-layer MnPS structures with staggered stacking configurations trigger outstanding UV photosensing performances, displaying an average EQE value of 1.

Metal dimer nanojunction-magnetic material composites for magnetic field sensing.

Noble metal nanocrystals are used as high sensitivity optoelectronic sensors, such as surface-enhanced Raman scattering, SERS. The sensing performance of metal nanocrystals can be further improved by forming dimer nanojunctions with strong "plasmonic coupling". Since the strength of "plasmonic coupling" is highly sensitive to the sub-nanoscale spacing between plasmonic nanocrystals in nanojunctions, nanojunctions can be used to detect external stimuli that can change the spacing of nanocrystals in the nanojunction and thus change the sensitivity of the Raman scattering spectrum.

Identifying Human miRNA Target Sites via Learning the Interaction Patterns between miRNA and mRNA Segments.

miRNAs (microRNAs) target specific mRNA (messenger RNA) sites to regulate their translation expression. Although miRNA targeting can rely on seed region base pairing, animal miRNAs, including human miRNAs, typically cooperate with several cofactors, leading to various noncanonical pairing rules. Therefore, identifying the binding sites of animal miRNAs remains challenging.

Are algorithmically controlled gig workers deeply burned out? An empirical study on employee work engagement.

Background: With the emergence of the gig economy as a new economic form, the influence of algorithmic technology control on gig workers' perceptions and engagement has become a topic of academic concern. This study explores the emotional impact of perceived algorithmic control on gig workers and how it affects their work engagement.

Methods: This study takes gig workers as the research object to build a structural equation model.

Lone-pair, electron-dominated, nonlinear optical responses in sulfur clusters and electric tunability properties.

Sulfur clusters have abundant lone-pair electrons, tunable geometries, and electronic structures, thus providing a new concept for achieving a tradeoff between transparency and nonlinearity. In this study, the optical properties of the sulfur clusters were investigated through first-principles calculations. Sulfur clusters exhibit broad transmittance bands spanning from the visible to the far-infrared regions, moderate third-order nonlinear optical effects comparable to those of -nitroaniline, and size-dependent third-order nonlinear anisotropy.

Acoustofluidics-Assisted Coating of Microparticles.

Microparticles have been applied in many areas, ranging from drug delivery, diagnostics, cosmetics, personal care, and the food industry to chemical and catalytic reactions, sensing, and environmental remediation. Coating further provides additional functionality to the microparticles, such as controlled release, surface modification, bio-fouling resistance, stability, protection, etc. In this study, the conformal coating of microparticles with a positively charged polyelectrolyte (polyallylamine hydrochloride, PAH) by utilizing an acoustofluidic microchip was proposed and demonstrated.

Effect of morphologies and compositions of silver-based multicomponent heterogeneous nanocrystals on the reduction of 4-nitrophenol.

Silver-based nanocrystals have excellent catalytic performance in various reactions, such as the reduction of 4-nitrophenol. The catalytic performance of nanocrystals varies with several parameters, including nanocrystal morphology, composition, and plasmon-induced hot electrons around nanocrystals. Here, highly heterogeneous nanocrystals (Au-Ag and AgS-Ag nanocrystals) fabricated on polymer films a seed-mediated method are used as catalysts for the reduction of 4-nitrophenol, and the effect of the morphology and composition of nanocrystals on the catalytic performance is investigated.