- The study aimed to identify specific serum protein profiles associated with ovarian cancer by comparing samples from 36 cancer patients and 30 healthy individuals using specialized mass spectrometry.
- Researchers found 29 protein peaks that were significantly different between the groups, with three specific peaks identified as potential ovarian cancer biomarkers, displaying high sensitivity and specificity.
- The findings support that serum biomarkers can help diagnose ovarian cancer and detect cases related to drug resistance, particularly through the expression of MDR1 and MRP proteins in patients.