232 results match your criteria: "No 1. University Road[Affiliation]"

Coalfield fire area reburning is one of the serious disasters in fire prevention and safety production. In this study, a synchronous thermal analyzer was used to conduct isothermal pyrolysis of jet coal at different temperatures, and the reaction characteristic parameters of different pyrolysis residual structures were analyzed. FTIR was used to measure group contents in raw coal and different pyrolysis residues.

View Article and Find Full Text PDF

Background: Prolonged life expectancy is associated with increased prevalence of chronic diseases. The aim of this study was to determine the different disability trajectories for the top ten leading causes of death in Taiwan .

Methods: A total of 2,431 participants aged 50-96 in 1996 from the Taiwan longitudinal study on aging (TLSA) who died from 1996 to 2016 were analyzed.

View Article and Find Full Text PDF

The evaluation of zebrafish cardiovascular and behavioral functions through microfluidics.

Sci Rep

July 2021

Department of Mechanical Engineering, National Cheng Kung University, No. 1 University Road, Tainan, 701, Taiwan.

This study proposed a new experimental approach for the vascular and phenotype evaluation of the non-anesthetized zebrafish with representative imaging orientations for heart, pectoral fin beating, and vasculature views by means of the designed microfluidic device through inducing the optomotor response and hydrodynamic pressure control. In order to provide the visual cues for better positioning of zebrafish, computer-animated moving grids were generated by an in-house control interface which was powered by the larval optomotor response, in conjunction with the pressure suction control. The presented platform provided a comprehensive evaluation of internal circulation and the linked external behaviors of zebrafish in response to the cardiovascular parameter changes.

View Article and Find Full Text PDF

Automated Radiology Alert System for Pneumothorax Detection on Chest Radiographs Improves Efficiency and Diagnostic Performance.

Diagnostics (Basel)

June 2021

Department of Medical Imaging, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 1 University Road, Tainan 704, Taiwan.

We aimed to set up an Automated Radiology Alert System (ARAS) for the detection of pneumothorax in chest radiographs by a deep learning model, and to compare its efficiency and diagnostic performance with the existing Manual Radiology Alert System (MRAS) at the tertiary medical center. This study retrospectively collected 1235 chest radiographs with pneumothorax labeling from 2013 to 2019, and 337 chest radiographs with negative findings in 2019 were separated into training and validation datasets for the deep learning model of ARAS. The efficiency before and after using the model was compared in terms of alert time and report time.

View Article and Find Full Text PDF

Synthetic polymers are the most commonly used polymers in daily life. Therefore, it is necessary to develop environmentally friendly polymers. Hydroxypropyl methylcellulose (HPMC) is a potential candidate for a biopolymer, owing to its unique properties.

View Article and Find Full Text PDF

Treatment of grating stimulation has been used in amblyopia for decades, but high dropout rate and inconvenience for daily practice occur in previous studies. We developed a home-based portable system with rotating grating stimulation on a tablet. Thirty anisometropic amblyopic children were randomly allocated into the control or Grating group.

View Article and Find Full Text PDF

Hydrogel ionotronics are intriguing soft materials that have been applied in wearable electronics and artificial muscles. These applications often require the hydrogels to be tough, transparent, and 3D printable. Renewable materials like cellulose nanocrystals (CNCs) with tunable surface chemistry provide a means to prepare tough nanocomposite hydrogels.

View Article and Find Full Text PDF

Polymethyl methacrylate plates are widely applied to buildings, producing significant fire hazards. It lacks a theoretical basis for the fire risk assessment of polymethyl methacrylate in concave building facades. Therefore, experimental methods are used to investigate combustion characteristics of discrete polymethyl methacrylate plates in a concave building facade.

View Article and Find Full Text PDF

Comprehensive Hydrodynamic Investigation of Zebrafish Tail Beats in a Microfluidic Device with a Shape Memory Alloy.

Micromachines (Basel)

January 2021

Department of Mechanical Engineering, National Cheng Kung University, No. 1 University Road, Tainan 701, Taiwan.

Article Synopsis
  • The zebrafish is a key model for studying biomechanics and the effects of food toxicity, particularly through its tail movements during swimming.
  • A new microfluidic device with a shape memory alloy actuator was created to study the zebrafish's hydrodynamic responses while being exposed to food additives.
  • By analyzing the zebrafish's behavior during early development, this research offers valuable insights for using zebrafish in drug discovery and understanding human health responses.
View Article and Find Full Text PDF

In-Situ Investigation on Nanoscopic Biomechanics of at Low pH Citric Acid Environments Using an AFM Fluid Cell.

Int J Mol Sci

December 2020

Department of Materials Science and Engineering, National Cheng Kung University, Taiwan No.1 University Road, East District, Tainan 701, Taiwan.

() is widely regarded as the main cause of human dental caries via three main virulence factors: adhesion, acidogenicity, and aciduricity. Citric acid is one of the antibiotic agents that can inhibit the virulence capabilities of . A full understanding of the acidic resistance mechanisms (ARMs) causing bacteria to thrive in citrate transport is still elusive.

View Article and Find Full Text PDF

Human HLTF participates in the lesion-bypass mechanism through the fork reversal structure, known as template switching of post-replication repair. However, the mechanism by which HLTF promotes the replication progression and fork stability of damaged forks remains unclear. Here, we identify a novel protein-protein interaction between HLTF and PARP1.

View Article and Find Full Text PDF

Effects of Overlap Length on Flammability and Fire Hazard of Vertical Polymethyl Methacrylate (PMMA) Plate Array.

Polymers (Basel)

November 2020

Key Laboratory of Mining Disaster Prevention and Control, Qingdao 266590, China.

Polymethyl methacrylate (PMMA) plates are widely used in buildings or factories for natural lighting. Commonly PMMA plates are installed as a discrete array. However, PMMA plates are very susceptible to fire.

View Article and Find Full Text PDF

Experimental Study on Flammability and Flame Spread Characteristics of Polyvinyl Chloride (PVC) Cable.

Polymers (Basel)

November 2020

Key Laboratory of Mining Disaster Prevention and Control, Qingdao 266590, China.

Polyvinyl chloride (PVC) is widely applied in cables as insulation materials, which are vital for operation and control of industrial processes. However, PVC cables fires frequently occur, arousing public concern. Therefore, experimental methods are used to study flammability and flame-spread characteristics of PVC cable in this paper.

View Article and Find Full Text PDF

Gas sensing to recognize volatile liquids is successfully conducted through pipe-guided terahertz (THz) radiation in a reflective and label-free manner. The hollow core of a pipe waveguide can efficiently deliver the sensing probe of the THz confined waveguide fields to any place where dangerous vapors exist. Target vapors that naturally diffuse from a sample site into the pipe core can be detected based on strong interaction between the probe and analyte.

View Article and Find Full Text PDF

Tunable Optical Property of Plasmonic-Polymer Nanocomposites Composed of Multilayer Nanocrystal Arrays Stacked in a Homogeneous Polymer Matrix.

ACS Appl Mater Interfaces

November 2020

Department of Chemical Engineering, National Cheng Kung University, No. 1 University Road, East Dist., Tainan City 70101, Taiwan, R.O.C.

Layer-by-layer (LbL) synthetic technique has been used to deposit multilayers composed of a wide range of materials including polymers, colloidal particles, and biomolecules. A more complex organization of nanocomponents-within layers (intralayer) and across layers (interlayer)-beyond simple deposition is required for manufacturing next-generation materials and devices. Recently, LbL was used to fabricate multilayer stacked polymer-nanocrystal nanocomposites composed of a stacking sequence of two immiscible polymer thin films.

View Article and Find Full Text PDF

One-Step Hot Microembossing for Fabrication of Paper-Based Microfluidic Chips in 10 Seconds.

Polymers (Basel)

October 2020

Department of Chemical Engineering, National Cheng Kung University, No.1 University Road, Tainan 70101, Taiwan.

In recent years, microfluidic paper-based analytical devices (µPADs) have been developed because they are simple, inexpensive and power-free for low-cost chemical, biological and environmental detection. Moreover, paper is lightweight; easy to stack, store and transport; biodegradable; biocompatible; good for colorimetric tests; flammable for easy disposal of used paper-based diagnostic devices by incineration; and can be chemically modified. Different methods have been demonstrated to fabricate µPADs such as solid wax printing, craft cutting, photolithography, etc.

View Article and Find Full Text PDF

Food coloring is often used as a coloring agent in foods, medicines and cosmetics, and it was reported to have certain carcinogenic and mutagenic effects in living organisms. Investigation of physiological parameters using zebrafish is a promising methodology to understand disease biology and drug toxicity for various drug discovery on humans. Zebrafish (Danio rerio) is a well-acknowledged model organism with combining assets such as body transparency, small size, low cost of cultivation, and high genetic homology with humans and is used as a specimen tool for the in-vivo throughput screening approach.

View Article and Find Full Text PDF

Evaluating nitrite oxidizing organism survival under different nitrite concentrations.

Water Sci Technol

July 2020

Faculty of Environmental Engineering, University of Kitakyushu, 1-1, Hibikino, Wakamatsu, Kitakyushu, 808-0135, Japan.

The objective of this study is to explore the optimal pre-treatment procedures and statistics methods for live/dead bacterial staining using nitrite oxidizing organism (NOO) as the research aim. This staining method was developed and widely utilized to evaluate activated bacterial survival situation, because it is direct and convenience to count live and dead bacteria amount by colour distinguishes (green/red) from pictures taken by microscope. The living cell (green colour) percentage and initial bacterial chemical oxygen demand (COD) could be used for accurate reaction rate calculation at the beginning of tests.

View Article and Find Full Text PDF

Ester-mediated peptide formation promoted by deep eutectic solvents: a facile pathway to proto-peptides.

Chem Commun (Camb)

October 2020

Department of Chemical Engineering, National Cheng Kung University, No. 1 University Road, Tainan City, 70101, Taiwan, Republic of China.

The ester-amide exchange reaction enables spontaneous formation of prebiotic proto-peptides under mild conditions. However, this reaction also leads to oligomers with a vast sequence diversity of ester and amide linkages. Here, we demonstrate using deep eutectic solvents as a universal strategy to regulate the reaction pathways and promote the formation of amino acid-enriched oligomers with peptide backbones.

View Article and Find Full Text PDF

Thin gold (Au) films (10 nm) are deposited on different substrates by using a e-beam deposition system. Compared with sapphire and SiO surfaces, longer migration length of the Au adatoms is observed on MoS surfaces, which helps in the formation of a single-crystal Au film on the MoS surface at 200 °C. The results have demonstrated that with the assistance of van der Waals epitaxy growth mode, single-crystal 3D metals can be grown on 2D material surfaces.

View Article and Find Full Text PDF

Cancer metastasis is a central oncology concern that worsens patient conditions and increases mortality in a short period of time. During metastatic events, mitochondria undergo specific physiological alterations that have emerged as notable therapeutic targets to counter cancer progression. In this study, we use drug-free, cationic peptide fibrillar assemblies (PFAs) formed by poly(L-Lysine)--poly(L-Threonine) (Lys--Thr) to target mitochondria.

View Article and Find Full Text PDF

Enhancement of Hippocampal Spatial Decoding Using a Dynamic Q-Learning Method With a Relative Reward Using Theta Phase Precession.

Int J Neural Syst

September 2020

Department of Neurology of the Second Affiliated Hospital, Interdisciplinary Institute of Neuroscience and Technology, Key Laboratory of Medical Neurobiology of Zhejiang Province, Zhejiang University School of Medicine, Hangzhou 310029, P. R. China.

Hippocampal place cells and interneurons in mammals have stable place fields and theta phase precession profiles that encode spatial environmental information. Hippocampal CA1 neurons can represent the animal's location and prospective information about the goal location. Reinforcement learning (RL) algorithms such as Q-learning have been used to build the navigation models.

View Article and Find Full Text PDF

Nickel-based catalysts play an important role in the hydrogen-free deoxygenation for the production of biofuel. The yield and quality of the biofuel are critically affected by the physicochemical properties of NiO supported on nanosized zeolite Y (Y65, crystal size of 65 nm). Therefore, 10 wt% NiO supported on Y65 synthesized by using impregnation (IM) and deposition-precipitation (DP) methods were investigated.

View Article and Find Full Text PDF

Cloning and promoter analysis of palladin 90-kDa, 140-kDa, and 200-kDa isoforms involved in skeletal muscle cell maturation.

BMC Res Notes

July 2020

Department of Life Sciences, College of Biosciences and Biotechnology, National Cheng Kung University, No. 1 University Road, East Dist.,, Tainan City, 701, Taiwan (R.O.C.).

Objective: Palladin is a ubiquitous phosphoprotein expressed in vertebrate cells that works as a scaffolding protein. Several isoforms deriving from alternative splicing are originated from the palladin gene and involved in mesenchymal and muscle cells formation, maturation, migration, and contraction. Recent studies have linked palladin to the invasive spread of cancer and myogenesis.

View Article and Find Full Text PDF

Lamellar assembly in unusual sector-face PLLA spherulites from crystallization of poly(L-lactic acid) (PLLA) diluted with amorphous poly(methyl methacrylate) (PMMA). The growth and morphology of the crystalline structures is studied using polarized optical microscopy (POM), atomic-force and scanning electron microscopies (AFM, SEM). Crystals are also analyzed using differential scanning calorimetry (DSC) and small-angle X-ray scattering (SAXS).

View Article and Find Full Text PDF