360 results match your criteria: "Nippon Dental University School of Life Dentistry at Niigata[Affiliation]"

The purpose of this study was to examine the effects of combining specific adhesive materials and various surface treatments on bonding durability and microleakage of vertically fractured roots. Adhesive models were prepared using bovine lower incisors. The experiment included the following five groups: SB-G group (control) (10% citric acid with 3% ferric chloride solution (10-3 solution) + an adhesive resin cement (4-META/MMA-TBB; Super-Bond)), EC group (self-cure bonding agent (UB) + core composite resin (EC)), EC-G group (10-3 solution + UB + EC), EC-P group (40% phosphate solution + UB + EC), and EC-E group (18% ethylenediaminetetraacetic acid (EDTA) solution + UB + EC).

View Article and Find Full Text PDF

Background/aim: Root length is a critical factor for dental pulp regeneration following tooth replantation. The aim of this study was to analyze the effects of reducing the root length by apicoectomy on the pulp healing process using a model for tooth replantation.

Material And Methods: After extraction of the upper first molars (M1) of 3-week-old mice, the roots from the experimental group (EG) were shortened to half to two-thirds of their length before replantation, whereas in the control group (CG) the extracted teeth were immediately repositioned into their alveolar sockets.

View Article and Find Full Text PDF

Photocatalysts have attracted attention in the medical field for their antibacterial effects. However, typical photocatalysts are activated by ultraviolet rays, which may have adverse effects. Therefore, we focused on a new photocatalyst that is activated by visible light, hydroxyapatite (HAp), and amino acid complex with gray titania, and evaluated its antibacterial effects against Porphyromonas gingivalis and effect by toothbrushing.

View Article and Find Full Text PDF

Purpose: The purpose of this study was to evaluate the cone-beam computed tomographic (CBCT) imaging and histopathological characteristics of osteoradionecrosis (ORN) and medication-related osteonecrosis of the jaw (MRONJ).

Materials And Methods: Ten surgical specimens from segmental mandibulectomy (3 ORN and 7 MRONJ) were analyzed using CBCT. The CBCT parameters were as follows: high-resolution mode (tube voltage, 90.

View Article and Find Full Text PDF

Pulp tissue reaction to a self-adhesive, resin-based direct pulp capping material containing surface pre-reacted glass-ionomer filler.

Dent Mater

June 2021

Advanced Operative Dentistry-Endodontics, The Nippon Dental University Graduate School of Life Dentistry at Niigata, Japan; Department of Operative Dentistry, The Nippon Dental University School of Life Dentistry at Niigata, Japan. Electronic address:

Objective: This study aimed to evaluate the effect of direct pulp capping using an experimental self-adhesive resin for direct pulp capping (SRD) containing silica and surface pre-reacted glass-ionomer (S-PRG) filler on pulpal healing and to monitor the dentin bridge formation in rat pulp 2-4 weeks after operation.

Methods: Five types of SRDs (SRD-0: S-PRG fillers 0 wt%; SRD-1: S-PRG fillers 9.1 wt%; SRD-2: S-PRG fillers 18.

View Article and Find Full Text PDF
Article Synopsis
  • A study explored the effectiveness of combining the anticancer drug paclitaxel (PTX) with cetuximab (cMab) for treating head and neck cancer, while highlighting the need for personalized treatment to avoid serious side effects.
  • Researchers utilized a culture drug sensitivity test (CD-DST) to determine the optimal concentration of PTX for cancer cell lines, finding that 0.1 μg/mL resulted in dose-dependent sensitivity and correlated well with results in mice.
  • The findings suggest that CD-DST can help predict the effectiveness of PTX alone and when combined with cMab, potentially improving treatment outcomes for patients with oral squamous cell carcinoma.
View Article and Find Full Text PDF

Collagen-Based Matrices for Osteoconduction: A Preclinical In Vivo Study.

Biomedicines

February 2021

Department of Cranio-Maxillofacial Surgery, Inselspital, Bern University Hospital, Faculty of Medicine, University of Berne, CH-3010 Berne, Switzerland.

The aim of this study was to evaluate the influence of additional hydroxyapatite (HA) in collagen-based matrices (CM) and membrane placement on bone formation in calvarial defects. Critical size defects in the calvaria of 16 New Zealand White Rabbits were randomly treated with CM or mineralized collagen-based matrices (mCM). Half of the sites were covered with a collagen membrane.

View Article and Find Full Text PDF

Background/aim: Wearing a mouthguard reduces the risk of sport-related injuries, but the thickness has a large effect on its efficacy and safety. The aim of this study was to investigate the effect on the thickness of a single-layer mouthguard of the positional relationship between the suction port of the vacuum forming device and the model.

Materials And Methods: Ethylene-vinyl-acetate sheets of 4.

View Article and Find Full Text PDF

Background: Mouthguard should be worn to decrease orofacial trauma. Custom-made mouthguards are usually fabricated using ethylene vinyl acetate sheet or polyolefin sheet. However, the difference of the characteristics of the mouthguard formed by polyolefin sheet has not been cleared enough.

View Article and Find Full Text PDF

Purpose: The present study aimed to investigate the relationships between the crown form of the upper central incisor and their labial inclination, overbite, and overjet.

Materials And Methods: Maxillary and mandibular casts of 169 healthy dentitions were subjected to 3D dental scanning, and analyzed using CAD software. The crown forms were divided into tapered, square, and ovoid based on the mesiodistal dimensions at 20% of the crown height to that at 40%.

View Article and Find Full Text PDF

In vitro Activity of Oral Health Care Products on Candida Biofilm Formation.

Monogr Oral Sci

January 2021

Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland,

The activity of mouthwash ingredients used in daily oral care (chlorhexidine digluconate, benzalkonium chloride, povidone iodine solution, tea tree oil) and of nystatin was evaluated not only on planktonic Candida albicans or C. glabrata, but also on the inhibition of biofilm formation. A microbroth dilution technique was used to determine the minimum inhibitory concentration of the substances against two laboratory strains and seven clinical isolates.

View Article and Find Full Text PDF

Effects of plastic bracket primer on the shear bond strengths of orthodontic brackets.

J Dent Sci

January 2021

Orthodontics and Dentofacial Orthopedics, Field of Oral and Maxillofacial Growth and Development, Course of Clinical Science, The Nippon Dental University Graduate School of Life Dentistry at Niigata, Niigata, Japan.

Background/purpose: To assess the usefulness of plastic bracket primer (PBP) for improving the bond strength of plastic brackets (PBs) using three types of orthodontic brackets, including PBs, metal brackets (MBs), and ceramic brackets (CBs).

Materials And Methods: A total of 162 premolars were gathered and divided equally into six groups of 27. Three groups were tested with the application of PBP (PB+, MB+, and CB+), and three groups were tested without primer (groups PB-, MB-, and CB-).

View Article and Find Full Text PDF

Background/aim: Mouthguard thickness should be maintained to prevent oral trauma by protecting the teeth and the surrounding soft tissue. The aim of this study was to examine the difference in laminated mouthguard thickness according to the laminate order.

Materials And Methods: The mouthguard sheets used in this study were 2.

View Article and Find Full Text PDF

Few prospective studies have reported the effects of periodontal therapy on patients who attempted to quit smoking. This study aimed to assess how smoking cessation affects periodontal therapy. Twenty-five smokers with periodontitis were investigated by dividing them into two groups, a smoking cessation support group and a continued smoking group.

View Article and Find Full Text PDF

Background: Self-care and professional care of implants may prove difficult for elderly people who require nursing care. However, the actual state of care and problems remains unknown. In this study, we investigated the actual state of implant problems in elderly people living in their own home or in a nursing home who received visiting dental treatment.

View Article and Find Full Text PDF

Bone single-photon emission computed tomography-CT peak standardized uptake value for chronic osteomyelitis, osteoradionecrosis and medication-related osteonecrosis of the jaw.

J Med Imaging Radiat Oncol

April 2021

Quantitative Diagnostic Imaging, Field of Oral and Maxillofacial Imaging and Histopathological Diagnostics, Course of Applied Science, The Nippon Dental University Graduate School of Life Dentistry at Niigata, Niigata, Japan.

Article Synopsis
  • This study examined the peak standardized uptake value (SUV) in SPECT-CT imaging to differentiate between chronic osteomyelitis, osteoradionecrosis, and medication-related osteonecrosis of the jaw (MRONJ).
  • A total of 65 patients were assessed, revealing that chronic osteomyelitis had a significantly higher peak SUV compared to the other conditions.
  • The findings suggest that peak SUV measurement can effectively aid in the evaluation and diagnosis of these jaw lesions.
View Article and Find Full Text PDF

Tooth plates of the chimaeroids, holocephalian fishes, are unique dental hard tissues. Unlike the teeth of other animals, the tooth plates are located on the roof of the mouth and in the lower jaw. Their tooth plates consist, to a large extent, of lightly mineralized tissue (osteodentin) and hypermineralized tissue (pleromin).

View Article and Find Full Text PDF

Oral dryness as a side effect of certain drugs is increasing. The aim of this study was to examine the change of the protein ingredient in saliva of oral dryness patients caused by calcium blocker. Six patients taking calcium blocker and six healthy elderly were enrolled.

View Article and Find Full Text PDF

A previous study indicated that the swallowing reflex is inhibited during rhythmic jaw movements induced by electrical stimulation of the anterior cortical masticatory area. Rhythmic jaw movements were induced by electrical stimulation of the central amygdaloid nucleus (CeA). The swallowing central pattern generator is the nucleus of the solitary tract (NTS) and the lateral reticular formation in the medulla.

View Article and Find Full Text PDF

Purpose: Prevention of xerostomia and stress is important to prolong healthy life expectancy and improve the quality of life. We aimed to investigate the effects of tongue rotation exercise for increasing salivary secretions and stabilizing salivary stress hormone levels.

Materials And Methods: Twenty four participants without subjective oral dryness were enrolled.

View Article and Find Full Text PDF

Capsaicin powerfully evokes the swallowing reflex and is a known therapeutic agent for improving dysphagia and preventing aspiration pneumonia. However, the role of capsaicin-sensitive nerves in the initiation of swallowing evoked by various natural stimuli remains unclear. To explore this question, we blocked laryngeal capsaicin-sensitive nerves following the coapplication of QX-314 and capsaicin (QX/Cap), and investigated the effects on swallowing evoked by mechanical and chemical stimulation in anesthetized rats.

View Article and Find Full Text PDF

The sequential oral functions of mastication and swallowing are well tuned in humans. To prevent oral hypofunction as a risk factor for systemic frailty by oral motor training, semi-powered exoskeleton was developed and evaluated its loading/assist effects by monitoring electromyography signals and saliva secretion in healthy persons. The actuator of the driving unit combined mechanical and powered mechanics and was driven alternatively by an unpowered stainless-steel spring system for jaw-opening training by loading and a powered shape-memory alloy spring system to assist jaw closing.

View Article and Find Full Text PDF

Background/aim: The effectiveness and safety of mouthguards are affected by their thickness. The aim of this study was to investigate the effect of an acute angle model on the mouthguard thickness with the thermoforming method in which the model position was moved just before fabrication.

Materials And Methods: Mouthguards were thermoformed using 4.

View Article and Find Full Text PDF

The aim of this study was to examine the effect of various surface treatments on the bond strength of a resin luting agent and the surface roughness and surface energy of computer-aided design and computer-aided manufacturing (CAD/CAM) materials. Four types of CAD/CAM blocks (Shofu Block HC: BHC; GC Cerasmart: CER; VITA Enamic: ENA; and Lava Ultimate: LAV) were used. All blocks were randomly divided into eight groups based on the surface treatment as follows: no surface treatment (C), airborne-particle abrasion (AA), hydrofluoric acid etching (HA), silane coupling agent application (SL), AA/SL, HA/SL, AA/HA, and AA/HA/SL.

View Article and Find Full Text PDF

Currently, it is difficult to extract exosomes with stable physicochemical properties from saliva. Furthermore, due to inadequate availability of basic data, the application of salivary exosomes as a diagnostic material is limited. In this study, we aimed to investigate an easier method for extraction of exosomes from whole saliva and compared proteins in salivary exosomes derived from subjects of two age groups.

View Article and Find Full Text PDF