361 results match your criteria: "Nippon Dental University School of Life Dentistry at Niigata[Affiliation]"

Background/aim: The thermal shrinkage that occurs when the extrusion molding sheet is heated affects the mouthguard thickness. The aim of this study was to investigate the effect of sheet extrusion direction on laminated mouthguard thickness.

Materials And Methods: Mouthguards were pressure formed using the extruded sheet and a plaster model.

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Introduction: Parapharyngeal space infection may lead to severe and potentially life-threatening complications. The aim of this study was to assess the odontogenic infection pathway to the parapharyngeal space using CT imaging.

Materials And Methods: Nineteen patients in mandibular odontogenic infections with abscess who underwent contrast-enhanced CT were evaluated in this study.

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The purpose of this study was to investigate the characteristics and the detection ability of vertical root fractures in endodontically treated teeth by intraoral radiography and cone-beam computed tomography (CBCT). CBCT images of 50 patients with root fractures in endodontically treated teeth were reviewed, and 36 vertical root fractures were taken in this study. The cause of fracture, core construction, kind of teeth, and fracture direction (bucco-lingual and mesio-distal fractures) were investigated.

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Background/aim: Mouthguard thickness is important to prevent oral and facial trauma during sports. The aim of this study was to establish an effective thermoforming method for maintaining mouthguard thickness with a circular sheet using a circular frame.

Materials And Methods: Mouthguards were thermoformed using 4.

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Background/aim: Mouthguards must have an appropriate thickness to prevent oral trauma during sports. The aim of this study was to establish a thermoforming technique to secure the labial and buccal thicknesses of the mouthguard with a single sheet.

Materials And Methods: Mouthguards were thermoformed using 4.

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Background/aim: Mouthguard thickness influences the protection ability from orofacial trauma. The aim of this study was to propose a new design for mouthguards and to evaluate the effect of the lamination order on the thicknesses of mouthguards.

Materials And Methods: Mouthguard sheets of 2.

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Objective data mainly from the comparative anatomy of various organs related to human speech and language is considered to unearth clues about the mechanisms behind language development. The two organs of the larynx and hyoid bone are considered to have evolved towards suitable positions and forms in preparation for the occurrence of the large repertoire of vocalization necessary for human speech. However, some researchers have asserted that there is no significant difference of these organs between humans and non-human primates.

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Objectives: Original odontoblasts and regenerated odontoblast-like cells (OBLCs) may differently regulate Nestin expression. This study aimed to investigate the role of the subodontoblastic layer (SOBL) using green fluorescent protein (GFP) reactivity in the process of OBLC differentiation after tooth drilling in Nestin-enhanced GFP transgenic mice.

Methods: A groove-shaped cavity was prepared on the mesial surface of the maxillary first molars of 5- or 6-week-old mice under deep anesthesia.

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Introduction: The quantitative parameter was successfully derived from the quantitative bone SPECT/CT images. The aim of this study was to evaluate maximum standardized uptake value (SUV) of normal structures in the head and neck with bone SPECT/CT.

Methods: Fifty-three patients with jaw lesions (11 chronic osteomyelitis, eight osteoradionecrosis and 34 medication-related osteonecrosis of the jaw) who had bone SPECT/CT were prospectively included.

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Background/aim: Polyolefin sheet mouthguards are usually formed in the same manner as ethylene-vinyl acetate sheet mouthguards. However, the heating condition of the polyolefin sheet for the pressure-forming process has not been determined. The aim of this study was to examine the appropriate heating condition for polyolefin sheet mouthguards when fabricated with the pressure-formed technique.

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Oral disabilities occur due to tooth loss. This study aimed to investigate oral and systemic factors related to diet in elderly residents receiving domiciliary dental care. The subjects were 74 consenting residents.

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Genetically-encoded calcium indicators such as G-GECO are useful for studying Ca responses during long-term processes. In this study, we employed a lentiviral vector and established a rat dental epithelial cell line that stably expressed G-GECO (SF2-G-GECO). Ca imaging analysis under cell culture conditions revealed that SF2-G-GECO cells exhibited spontaneous Ca responses, which could be classified into the following three major patterns depending on the cell density: localized Ca responses at cell protrusions at a low density, a cell-wide spread of Ca responses at a medium density, and Ca responses in clusters of 3-20 cells at a high density.

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Multiple myeloma is characterized by a neoplastic proliferation of plasma cells primarily in the bone marrow. Neoplastic plasma cells stimulated osteoclasts, and destroy bone tissue, causing bone pain, pathological fractures, paralysis due to spinal cord compression, and hypercalcemia. Bisphosphonates are used as supportive therapy in the management of multiple myeloma.

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Detection and quantification of human-specific mRNA from hepatocyte-like cells derived from dental pulp using real-time polymerase chain reaction.

J Oral Biosci

September 2021

Clinical Examination, The Nippon Dental University Graduate School of Life Dentistry at Niigata, Niigata, Japan; Department of Internal Medicine, The Nippon Dental University School of Life Dentistry at Niigata, Niigata, Japan. Electronic address:

Article Synopsis
  • The study aimed to measure the presence of human hepatocyte-like cells (HLCs) in the livers and lungs of immunodeficient rats after they were administered through different routes (portal or tail veins) using real-time PCR.
  • Results showed that HLCs significantly reduced in the liver and mostly got trapped in the lungs, with a notable decrease in detectable human mRNA soon after infusion, regardless of liver injury.
  • The study concluded that real-time RT-PCR can effectively estimate the quantity of viable human cells in an animal model, providing insights into the fate of HLCs after administration.
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Background: Obstructive sleep apnea (OSA) has been suggested as an independent risk factor for nonalcoholic fatty liver disease (NAFLD), and continuous positive airway pressure (CPAP) is the first-line therapy for OSA.

Aim: To clarify the efficacy of effective CPAP therapy on NAFLD of OSA patients by serum markers and transient elastography (TE) using FibroScan (Echosens, Paris, France).

Methods: We prospectively enrolled 123 consecutive patients with OSA who met the indications for CPAP.

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A clinical pilot study of salivary gland secretion for xerostomia patients with Sjögren's syndrome using SPECT/CT.

Gerodontology

September 2022

Quantitative Diagnostic Imaging, Field of Oral and Maxillofacial Imaging and Histopathological Diagnostics, Course of Applied Science, The Nippon Dental University Graduate School of Life Dentistry at Niigata, Niigata, Japan.

Introduction: This study examined whether time-activity curves (TAC) can be used to differentiate between patients with and without Sjögren's syndrome using SPECT/CT.

Methods: Thirteen xerostomia patients (5 with Sjögren's syndrome and 8 without Sjögren's syndrome) underwent SPECT/CT. Salivary gland secretion data were digitally observed, producing separate time-activity curves (TAC) for the submandibular glands and parotid glands using SPECT/CT.

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The aim of this study was to investigate histologically the amount of peri-implant tissue augmentation after volume-stable porcine collagen matrix transplantation. Six male beagle dogs were used in the experiment. P2, P4, and M1 distal roots were extracted under general anesthesia.

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Coronavirus disease 2019 (COVID-19) is a highly transmissible pandemic disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The characteristics of the disease include a broad range of symptoms from mild to serious to death, with mild pneumonia to acute respiratory distress syndrome and complications in extrapulmonary organs. Taste impairment and salivary dysfunction are common early symptoms in COVID-19 patients.

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PTEN Is Activated by the Addition of Cetuximab to Paclitaxel in Oral Squamous Cell Carcinoma.

Anticancer Res

July 2021

Course of Clinical Science, Field of Oral and Maxillofacial Surgery and Systemic Medicine, Oral and Maxillofacial Surgery, Nippon Dental University Graduate School of Life Dentistry at Niigata, Niigata, Japan.

Background/aim: The mechanisms through which cetuximab (cMab) coadministration with paclitaxel (PTX) enhances antitumor efficacy remain unclear. We examined the mechanism of the antitumor enhancing effect of cMab by determining changes in gene expression in the PI3K-AKT pathway.

Materials And Methods: Eight human oral squamous cell carcinoma (OSCC) cell lines were cultured three-dimensionally and exposed to PTX + cMab.

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The purpose of this study was to determine whether a system using a resin coating material (PRG Barrier Coat) with anticariogenic ability can effectively bond orthodontic brackets to human teeth. Resin-modified glass-ionomer cement system (Fuji Ortho LC, group 1) and resin composite cement systems (BeautyOrtho Bond) combined with a self-etching primer (group 2), with the resin coating material (group 3), and with the resin coating material after an organic acid etching agent (group 4) were used for bracket bonding. The mean shear bond strength (SBS) was significantly higher in group 1 than in groups 2, 3 and 4.

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The purpose of this multicenter clinical study was to compare the mid-term clinical effectiveness of direct resin composite restorations using one-step or two-step self-etch adhesives (1-SEAs or 2-SEAs). In total, 352 restorations of class I-V cavities and non-carious cervical lesions in vital teeth (1-SEAs; 52 cases, 2-SEAs; 300 cases) were placed at nine university hospitals and evaluated according to the modified USPHS criteria at baseline, and after 1, 2, and 3 years. The recall rates were 86.

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This study aimed to investigate the effect of the multi-ion releasing paste (MP) on the acid resistance of the enamel surface of an extracted human tooth. Five kinds of MP were prepared according to the content (wt%) of S-PRG fillers: 0 wt% (MP0, control), 1 wt% (MP1), 5 wt% (MP5), 20 wt% (MP20), and 30 wt% (MP30). The buccal coronal surfaces of the extracted anterior teeth were polished with each kind of MP for 1 min.

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Analysis of medication-related osteonecrosis of the jaw with bone SPECT/CT: relationship between patient characteristics and maximum standardized uptake value.

Dentomaxillofac Radiol

December 2021

Quantitative Diagnostic Imaging, Field of Oral and Maxillofacial Imaging and Histopathological Diagnostics, Course of Applied Science, The Nippon Dental University Graduate School of Life Dentistry at Niigata, Niigata, Japan.

Objective: To analyze medication-related osteonecrosis of the jaw (MRONJ) with bone single photon emission computed tomography (SPECT)/CT, especially relationship between patient characteristics and maximum standardized uptake value (SUV).

Methods: 48 patients with MRONJ who underwent bone SPECT/CT were prospectively included. MRONJ patients were included 34 osteoporosis and 14 bone metastases from 6 lung cancer, 6 breast cancer and 2 rectal cancer.

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The present study aimed to evaluate the dentin bond strengths of all-in-one adhesives in combination with flowable-resin-composites of different manufacturers. The materials used in this study were two all-in-one adhesives (BeautiBond Multi, BM, and Clearfil Bond SE ONE, SE) and four flowable resin composites (Clearfil Majesty ES Flow, CME; Estelite Flow Quick, EFQ; MI Flow II, MIF; and Beautifil Flow Plus F03, BFP). By combining each all-in-one adhesive and flowable resin composite, eight experimental groups were established.

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