3 results match your criteria: "Ninth of July University (UNINOVE)[Affiliation]"
Impact on Survival with Immunotherapy and Evaluation of Biomarkers in Peruvian Patients with Advanced Melanoma.
Onco Targets Ther
November 2024
Medical Oncology Department, Instituto Nacional de Enfermedades Neoplásicas (INEN), Lima, Peru.
Introduction: Advanced malignant melanoma is a very aggressive disease, historically with poor prognosis before the new advances with immunotherapy and targeted therapies that have changed the standard of care, especially in cutaneous melanoma. Peru has aggressive features such as higher rates of acral lentiginous melanoma (ALM) subtype with historically shorter survival.
Methods: This study describes Peruvian patients with advanced melanoma treated with immunotherapy (nivolumab) in two oncological institutions (public and private), including the discussion of the impact on overall survival (OS) divided by subtype (with incidence in ALM histology) and potential biomarkers that could be related to prognosis.
PCNL vs. two staged RIRS for kidney stones greater than 20 mm: systematic review, meta-analysis, and trial sequential analysis.
Minerva Urol Nephrol
February 2024
Ninth of July University (UNINOVE), São Paulo, Brazil -
Introduction: Percutaneous nephrolithotomy (PCNL) is considered the gold standard treatment for kidney stones greater than 20 mm. However, retrograde intrarenal surgery (RIRS) may achieve the same stone-free rate with repeated procedures, and potentially fewer complications. This study aimed to compare the efficacy and safety of PCNL and two-staged RIRS.
View Article and Find Full Text PDFIntegrative microRNAome analysis of skeletal muscle of Colossoma macropomum (tambaqui), Piaractus mesopotamicus (pacu), and the hybrid tambacu, based on next-generation sequencing data.
BMC Genomics
April 2021
Department of Structural and Functional Biology, Institute of Biosciences, São Paulo State University - UNESP, Botucatu, Sao Paulo, 18618-970, Brazil.
Article Synopsis
- Colossoma macropomum (tambaqui) and Piaractus mesopotamicus (pacu) are valuable fish species for aquaculture, particularly the hybrid tambacu, which shows significant growth and strength, making it popular in Brazil.
- Small RNA sequencing was utilized to analyze miRNA expression across three fish genotypes: pacu, tambaqui, and hybrid tambacu, aiming to understand the muscle growth mechanisms in the hybrid.
- The study identified several differentially expressed miRNAs specific to genotype comparisons, with particular miRNAs linked to pathways involving oxygen regulation and muscle metabolism, highlighting their potential for enhancing fish farming efficiency.