3 results match your criteria: "Ningbo Diagnostic Pathology Center (Shanghai Cancer Center Ningbo Pathology Center)[Affiliation]"
Ezetimibe Prevents IL-1β-induced Inflammatory Reaction in Mouse Chondrocytes Modulating NF-κB and Nrf2/HO-1 Signaling Crosstalk.
Curr Pharm Biotechnol
October 2022
Department of Trauma Orthopedics, Ningbo No. 6 Hospital, Ningbo, China.
Background: Osteoarthritis is a type of age-related, chronic, and degenerative joint disease. Ezetimibe, a cholesterol absorption inhibitor, is widely used for the treatment of various diseases. However, the role of ezetimibe in osteoarthritis remains unclear.
View Article and Find Full Text PDFOverexpression of gene DEP domain containing 1 and its clinical prognostic significance in colorectal cancer.
J Clin Lab Anal
December 2020
Ningbo NO. 6 Hospital, Ningbo, China.
Background: Colorectal cancer (CRC) is one of the most commonly seen malignancies worldwide, yet its regulatory mechanisms still need to be further illuminated. Abundant evidence revealed that aberrant expression of cancer-related genes contributes to CRC progression. DEP domain containing 1 (DEPDC1) has been found to play a crucial role in the carcinogenesis and development of malignancies.
View Article and Find Full Text PDFLong noncoding RNAs in osteosarcoma via various signaling pathways.
J Clin Lab Anal
June 2020
Ningbo Diagnostic Pathology Center (Shanghai Cancer Center Ningbo Pathology Center), Ningbo, China.
Article Synopsis
- - Osteosarcoma is a common bone cancer affecting both kids and adults, but its development mechanisms remain largely unknown despite extensive research.
- - Recent studies have highlighted the significant role of long noncoding RNAs (lncRNAs) in osteosarcoma, influencing its progression and invasion through various molecular signaling pathways.
- - The review discusses specific lncRNAs, such as MALAT1 and CCAT2, that impact key signaling pathways like PI3K/Akt, Wnt/β-catenin, NF-κB, and others, suggesting potential avenues for therapeutic intervention.