1 results match your criteria: "Nihon University School of Medicine Division of Respiratory Disease[Affiliation]"
Protocadherin-1 is a glucocorticoid-responsive critical regulator of airway epithelial barrier function.
BMC Pulm Med
July 2015
Nihon University School of Medicine Division of Respiratory Disease, 30-1 Ohyaguchi-Kamicho, Itabashiku, Tokyo, 173-8610, Japan.
Background: Impaired epithelial barrier function renders the airway vulnerable to environmental triggers associated with the pathogenesis of bronchial asthma. We investigated the influence of protocadherin-1 (PCDH1), a susceptibility gene for bronchial hyperresponsiveness, on airway epithelial barrier function.
Methods: We applied transepithelial electric resistance and dextran permeability testing to evaluate the barrier function of cultured airway epithelial cells.