4 results match your criteria: "Nigeria. afukonyoshidoiku@tsuniversity.edu.ng.[Affiliation]"

Background: Atrial fibrillation (AF) is the most prevalent form of sustained cardiac arrhythmia, with vascular endothelial growth factor (VEGF) increasingly recognized for its potential role in the pathogenesis of AF through mechanisms involving atrial remodeling, inflammation, and fibrosis. This systematic review aims to synthesize available evidence on the association between VEGF and AF, exploring the implications of VEGF as a biomarker and therapeutic target.

Methods: We conducted a comprehensive search across PubMed, Embase, and Web of Science until November 10 2024, selecting studies based on pre-defined criteria that involve adults with AF and measurements of VEGF levels.

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Article Synopsis
  • People living with HIV (PLWH) face increased mortality risks from air pollution due to chronic inflammation and immune dysfunction, a link that has not been widely studied.
  • A systematic review analyzed nine studies, primarily from China, revealing that long-term exposure to pollutants like particulate matter significantly correlates with higher AIDS-related and overall mortality rates in PLWH, with certain populations being more susceptible.
  • The findings indicate that targeted interventions to lessen air pollution exposure could benefit vulnerable groups, emphasizing the need for further research in this area.
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Association of celiac disease and myocardial infarction: a systematic review and meta-analysis.

BMC Cardiovasc Disord

November 2024

Global Health and Infectious Diseases Control Institute, Nasarawa State University, Keffi, Nigeria.

Article Synopsis
  • Celiac disease (CD) is an autoimmune disorder linked to gluten intolerance that may affect cardiovascular health, with some studies suggesting a connection to myocardial infarction (MI), although results have been inconsistent.* -
  • A systematic review and meta-analysis of 8 studies were conducted to evaluate the risk of MI in adults with CD, using data from databases like PubMed and Web of Science, analyzed with R software.* -
  • The analysis found no significant association between CD and MI, but indicated high variability in study results, suggesting a need for more research on larger, more uniform samples to clarify potential cardiovascular risks for CD patients.*
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Risk of Hepatocellular Carcinoma with Glucagon-like Peptide-1 receptor agonist treatment in patients: a systematic review and meta-analysis.

BMC Endocr Disord

November 2024

Center for Global Health Research, Saveetha Institute of Medical and Technical Sciences, Saveetha Medical College and Hospital, Saveetha University, Chennai, India.

Background: Hepatocellular carcinoma (HCC) is a major cause of cancer-related mortality worldwide, with increased prevalence in individuals with chronic liver conditions and type 2 diabetes mellitus (T2DM). Glucagon-Like Peptide-1 Receptor Agonists (GLP-1 RAs) have shown promise in diabetes management and may influence liver disease progression. This systematic review and meta-analysis aimed to assess the efficacy of GLP-1 RAs in reducing the risk of HCC in patients with T2DM.

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