Universal Transitions between Growth and Dormancy via Intermediate Complex Formation.

A simple cell model consisting of a catalytic reaction network with intermediate complex formation is numerically studied. As nutrients are depleted, the transition from the exponential growth phase to the growth-arrested dormant phase occurs along with hysteresis and a lag time for growth recovery. This transition is caused by the accumulation of intermediate complexes, leading to the jamming of reactions and the diversification of components.

Structural characterisation of α-synuclein-membrane interactions and the resulting aggregation using small angle scattering.

The presence of amyloid fibrils is a hallmark of several neurodegenerative diseases. Some amyloidogenic proteins, such as α-synuclein and amyloid β, interact with lipids, and this interaction can strongly favour the formation of amyloid fibrils. In particular the primary nucleation step, the formation of amyloid fibrils, has been shown to be accelerated by lipids.

Genetic mixing and demixing on expanding spherical frontiers.

Genetic fluctuation during range expansion is a key process driving evolution. When a bacterial population is expanding on a 2D surface, random fluctuations in the growth of the pioneers at the front line cause a strong demixing of genotypes. Even when there is no selective advantage, sectors of low genetic diversity are formed.

Long-lived and Efficient Optomechanical Memory for Light.

We demonstrate a memory for light based on optomechanically induced transparency. We achieve a long storage time by leveraging the ultralow dissipation of a soft-clamped mechanical membrane resonator, which oscillates at MHz frequencies. At room temperature, we demonstrate a lifetime T_{1}≈23  ms and a retrieval efficiency η≈40% for classical coherent pulses.

Multimessenger Constraints on Radiatively Decaying Axions from GW170817.

The metastable hypermassive neutron star produced in the coalescence of two neutron stars can copiously produce axions that radiatively decay into O(100)  MeV photons. These photons can form a fireball with characteristic temperature smaller than 1 MeV. By relying on x-ray observations of GW170817/GRB 170817A with CALET CGBM, Konus-Wind, and Insight-HXMT/HE, we present new bounds on the axion-photon coupling for axion masses in the range 1-400 MeV.

Measurement of the Centrality Dependence of the Dijet Yield in p+Pb Collisions at sqrt[s_{NN}]=8.16 TeV with the ATLAS Detector.

ATLAS measured the centrality dependence of the dijet yield using 165  nb^{-1} of p+Pb data collected at sqrt[s_{NN}]=8.16  TeV in 2016. The event centrality, which reflects the p+Pb impact parameter, is characterized by the total transverse energy registered in the Pb-going side of the forward calorimeter.

Unveiling the Merger Structure of Black Hole Binaries in Generic Planar Orbits.

The precise modeling of binary black hole coalescences in generic planar orbits is a crucial step to disentangle dynamical and isolated binary formation channels through gravitational-wave observations. The merger regime of such coalescences exhibits a significantly higher complexity compared to the quasicircular case, and cannot be readily described through standard parametrizations in terms of eccentricity and anomaly. In the spirit of the effective one body formalism, we build on the study of the test-mass limit, and introduce a new modeling strategy to describe the general-relativistic dynamics of two-body systems in generic orbits.

Multistability and intermediate tipping of the Atlantic Ocean circulation.

Tipping points (TP) in climate subsystems are usually thought to occur at a well-defined, critical forcing parameter threshold, via destabilization of the system state by a single, dominant positive feedback. However, coupling to other subsystems, additional feedbacks, and spatial heterogeneity may promote further small-amplitude, abrupt reorganizations of geophysical flows at forcing levels lower than the critical threshold. Using a primitive-equation ocean model, we simulate a collapse of the Atlantic Meridional Overturning Circulation (AMOC) due to increasing glacial melt.

Diversity and ecotones in a model ecosystems of sessile species.

Sessile species compete for space and accessible light, with directed interactions evident in one species overgrowing another and with multispecies systems characterized by nontransitive relationships. Such patterns are observed in coral reefs or lichens on rock surfaces. Open systems with episodic invasions of such species have been predicted to exhibit a stable high-diversity state when the interaction probability is below a certain critical threshold.

Bending of a lipid membrane edge by annexin A5 trimers.

Plasma membrane damage occurs in healthy cells and more frequently in cancer cells where high growth rates and metastasis result in frequent membrane damage. The annexin family of proteins plays a key role in membrane repair. Annexins are recruited at the membrane injury site by Ca and repair the damaged membrane in concert with several other proteins.

Bayesian inference is facilitated by modular neural networks with different time scales.

Various animals, including humans, have been suggested to perform Bayesian inferences to handle noisy, time-varying external information. In performing Bayesian inference by the brain, the prior distribution must be acquired and represented by sampling noisy external inputs. However, the mechanism by which neural activities represent such distributions has not yet been elucidated.

Composite material in the sea urchin : ordered and disordered micrometre-scale bicontinuous geometries.

The sponge-like biomineralized calcite materials found in echinoderm skeletons are of interest in terms of both structure formation and biological function. Despite their crystalline atomic structure, they exhibit curved interfaces that have been related to known triply periodic minimal surfaces. Here, we investigate the endoskeleton of the sea urchin that has long been known to form a microstructure related to the Primitive surface.

A recently quenched galaxy 700 million years after the Big Bang.

Local and low-redshift (z < 3) galaxies are known to broadly follow a bimodal distribution: actively star-forming galaxies with relatively stable star-formation rates and passive systems. These two populations are connected by galaxies in relatively slow transition. By contrast, theory predicts that star formation was stochastic at early cosmic times and in low-mass systems.

Developmental hourglass: Verification by numerical evolution and elucidation by dynamical-systems theory.

Determining the general laws between evolution and development is a fundamental biological challenge. Developmental hourglasses have attracted increased attention as candidates for such laws, but the necessity of their emergence remains elusive. We conducted evolutionary simulations of developmental processes to confirm the emergence of the developmental hourglass and unveiled its establishment.

Most of the photons that reionized the Universe came from dwarf galaxies.

The identification of sources driving cosmic reionization, a major phase transition from neutral hydrogen to ionized plasma around 600-800 Myr after the Big Bang, has been a matter of debate. Some models suggest that high ionizing emissivity and escape fractions (f) from quasars support their role in driving cosmic reionization. Others propose that the high f values from bright galaxies generate sufficient ionizing radiation to drive this process.

Robustness and dosimetric verification of hippocampal-sparing craniospinal pencil beam scanning proton plans for pediatric medulloblastoma.

Background And Purpose: Hippocampal-sparing (HS) is a method that can potentially reduce late cognitive complications for pediatric medulloblastoma (MB) patients treated with craniospinal proton therapy (PT). The aim of this study was to investigate robustness and dosimetric plan verification of pencil beam scanning HS PT.

Materials And Methods: HS and non-HS PT plans for the whole brain part of craniospinal treatment were created for 15 pediatric MB patients.

Real-time two-axis control of a spin qubit.

Optimal control of qubits requires the ability to adapt continuously to their ever-changing environment. We demonstrate a real-time control protocol for a two-electron singlet-triplet qubit with two fluctuating Hamiltonian parameters. Our approach leverages single-shot readout classification and dynamic waveform generation, allowing full Hamiltonian estimation to dynamically stabilize and optimize the qubit performance.

Emission lines due to ionizing radiation from a compact object in the remnant of Supernova 1987A.

The nearby Supernova 1987A was accompanied by a burst of neutrino emission, which indicates that a compact object (a neutron star or black hole) was formed in the explosion. There has been no direct observation of this compact object. In this work, we observe the supernova remnant with JWST spectroscopy, finding narrow infrared emission lines of argon and sulfur.

A population of faint, old, and massive quiescent galaxies at [Formula: see text] revealed by JWST NIRSpec Spectroscopy.

Here we present a sample of 12 massive quiescent galaxy candidates at [Formula: see text] observed with the James Webb Space Telescope (JWST) Near Infrared Spectrograph (NIRSpec). These galaxies were pre-selected from the Hubble Space Telescope imaging and 10 of our sources were unable to be spectroscopically confirmed by ground based spectroscopy. By combining spectroscopic data from NIRSpec with multi-wavelength imaging data from the JWST Near Infrared Camera (NIRCam), we analyse their stellar populations and their formation histories.

A high black-hole-to-host mass ratio in a lensed AGN in the early Universe.

Early JWST observations have uncovered a population of red sources that might represent a previously overlooked phase of supermassive black hole growth. One of the most intriguing examples is an extremely red, point-like object that was found to be triply imaged by the strong lensing cluster Abell 2744 (ref. ).

A massive galaxy that formed its stars at z ≈ 11.

The formation of galaxies by gradual hierarchical co-assembly of baryons and cold dark matter halos is a fundamental paradigm underpinning modern astrophysics and predicts a strong decline in the number of massive galaxies at early cosmic times. Extremely massive quiescent galaxies (stellar masses of more than 10 M) have now been observed as early as 1-2 billion years after the Big Bang. These galaxies are extremely constraining on theoretical models, as they had formed 300-500 Myr earlier, and only some models can form massive galaxies this early.

ψ(2S) Suppression in Pb-Pb Collisions at the LHC.

The production of the ψ(2S) charmonium state was measured with ALICE in Pb-Pb collisions at sqrt[s_{NN}]=5.02  TeV, in the dimuon decay channel. A significant signal was observed for the first time at LHC energies down to zero transverse momentum, at forward rapidity (2.

Shear margins in upper half of Northeast Greenland Ice Stream were established two millennia ago.

Only a few localised ice streams drain most of the ice from the Greenland Ice Sheet. Thus, understanding ice stream behaviour and its temporal variability is crucially important to predict future sea-level change. The interior trunk of the 700 km-long North-East Greenland Ice Stream (NEGIS) is remarkable due to the lack of any clear bedrock channel to explain its presence.

Collectively enhanced Ramsey readout by cavity sub- to superradiant transition.

When an inverted ensemble of atoms is tightly packed on the scale of its emission wavelength or when the atoms are collectively strongly coupled to a single cavity mode, their dipoles will align and decay rapidly via a superradiant burst. However, a spread-out dipole phase distribution theory predicts a required minimum threshold of atomic excitation for superradiance to occur. Here we experimentally confirm this predicted threshold for superradiant emission on a narrow optical transition when exciting the atoms transversely and show how to take advantage of the resulting sub- to superradiant transition.