Bilateral spontaneous pneumothorax in a patient with rheumatoid arthritis and accelerated nodulosis.

https://bit.ly/3WBhgOe.

An optimized and validated protocol for inducing chronic experimental autoimmune encephalomyelitis in C57BL/6J mice.

Background: Myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis (EAE) is the most commonly used animal model of multiple sclerosis. However, variations in the induction protocol can affect EAE progression, and may reduce the comparability of data.

Optimized Method: In the present study, we investigated the influence of the different components used for EAE induction in C57BL/6J mice on disease progression.

Platelet Inhibition by Low-Dose Acetylsalicylic Acid Reduces Neuroinflammation in an Animal Model of Multiple Sclerosis.

Aside from the established immune-mediated etiology of multiple sclerosis (MS), compelling evidence implicates platelets as important players in disease pathogenesis. Specifically, numerous studies have highlighted that activated platelets promote the central nervous system (CNS)-directed adaptive immune response early in the disease course. Platelets, therefore, present a novel opportunity for modulating the neuroinflammatory process that characterizes MS.

Acute otitis externa: Consensus definition, diagnostic criteria and core outcome set development.

Objective: Evidence for the management of acute otitis externa (AOE) is limited, with unclear diagnostic criteria and variably reported outcome measures that may not reflect key stakeholder priorities. We aimed to develop 1) a definition, 2) diagnostic criteria and 3) a core outcome set (COS) for AOE.

Study Design: COS development according to Core Outcome Measures in Effectiveness Trials (COMET) methodology and parallel consensus selection of diagnostic criteria/definition.

Venous thromboembolism in orthopaedic oncology.

Aims: Malignancy and surgery are risk factors for venous thromboembolism (VTE). We undertook a systematic review of the literature concerning the prophylactic management of VTE in orthopaedic oncology patients.

Methods: MEDLINE (PubMed), EMBASE (Ovid), Cochrane, and CINAHL databases were searched focusing on VTE, deep vein thrombosis (DVT), pulmonary embolism (PE), bleeding, or wound complication rates.

A scoping review of trials for cell-based therapies in human spinal cord injury.

Introduction: Spinal cord injury (SCI) is associated with significant and life-long disability. Yet, despite decades of research, no regenerative treatment has reached clinical practice. Cell-based therapies are one possible regenerative strategy beginning to transfer to human trials from a more extensive pre-clinical basis.

Gait analysis with wearables predicts conversion to parkinson disease.

Objective: Quantification of gait with wearable technology is promising; recent cross-sectional studies showed that gait characteristics are potential prodromal markers for Parkinson disease (PD). The aim of this longitudinal prospective observational study was to establish gait impairments and trajectories in the prodromal phase of PD, identifying which gait characteristics are potentially early diagnostic markers of PD.

Methods: The 696 healthy controls (mean age = 63 ± 7 years) recruited in the Tubingen Evaluation of Risk Factors for Early Detection of Neurodegeneration study were included.

Is sharing speaker's slides from conference presentations on social media a breach of intellectual property or a delegate's right? Depends who you ask.

Background: The contemporary practice of the sharing of speaker's slides from medical conference presentations is common but raises a number of complex ethical and legal questions. We investigated the views of a large group of international hernia surgeons to evaluate the comtemporary view on this topic.

Methods: A questionnaire was widely promoted on Twitter and distributed by email to target the membership of the British and European Hernia Societies.

Social Media in Surgical Training: Opportunities and Risks.

Background: Surgeon engagement with social media is growing rapidly. Innovative applications in diverse fields of health care are increasingly available.

Objective: The aim of this review is to explore the current and future applications of social media in surgical training.

Correction to: The WOMAC score can be reliably used to classify patient satisfaction after total knee arthroplasty.

Unfortunately, Fig. 1 in the original article contained incorrect information. Hereby, the correct figure is published and we apologise for the inconvenience.

The WOMAC score can be reliably used to classify patient satisfaction after total knee arthroplasty.

Purpose: The primary aim of this study was to define a classification in the WOMAC score after total knee arthroplasty (TKA) according to patient satisfaction. The secondary aims were to describe patient demographics for each level of satisfaction.

Methods: A retrospective cohort consisting of 2589 patients undergoing a primary TKA were identified from an established arthroplasty database.

Social media use in German visceral surgeons: a cross-sectional study of a national cohort.

Aim: Engagement in social media is increasing. Medical professionals have been adapting LinkedIn, a professional networking site, and Twitter, a microblogging service, for a number of uses. This development has been described for a number of medical specialties, but there remains a paucity of European data.

Refining the head and neck cancer referral guidelines: a two centre analysis of 4715 referrals.

Our aim was to identify the set of referral criteria that will offer optimal diagnostic efficacy in patients suspected to have head and neck cancer (HNC) in the primary care setting. We analysed the referral criteria and outcomes from two tertiary care cancer centres in the United Kingdom. Between 2007 and 2010, 4715 patients were referred via the fast track system with a suspected HNC.

Refining the head and neck cancer referral guidelines: a two-centre analysis of 4715 referrals.

Objectives: To identify the set of referral criteria that will offer optimal diagnostic efficacy in patients suspected to have head and neck cancer (HNC) in the primary care setting.

Design: Statistical analysis of referral criteria and outcomes.

Setting: Two tertiary care cancer centres in the United Kingdom.

The risk of cardiorespiratory deaths persists beyond 30 days after proximal femoral fracture surgery.

Introduction: 30-day mortality is routinely used to assess proximal femoral fracture care, though patients might remain at risk for poor outcome for longer. This work has examined the survivorship out to one year of a consecutive series of patients admitted for proximal femoral fracture to a single institution. We wished to quantify the temporal impact of fracture upon mortality, and also the influence of patient age, gender, surgical delay and length of stay on mortality from both cardiorespiratory and non-cardiorespiratory causes.

Is undergraduate medical education working for ENT surgery? A survey of UK medical school graduates.

Background: Despite the patient numbers and scope of ENT surgery, it is under-represented in most undergraduate medical curricula.

Method: An online questionnaire was e-mailed, at National Health Service trust level, to 3,544 newly qualified doctors from 30 UK medical schools. Undergraduate ENT exposure, confidence and educational value were measured on a Likert scale.

Polymorphous low-grade adenocarcinoma of the head and neck.

Purpose Of Review: Polymorphous low-grade adenocarcinoma is an entity described in 1984. An increasing number of reports in the pathology literature since then have identified this as the second or the third most common minor salivary gland malignancy. The natural history of polymorphous low-grade adenocarcinoma is distinct from other malignant salivary tumours.