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Aims: To investigate the long-term effects of efavirenz on cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein (LDL-C) and triglycerides (TG).

Methods: Thirty-four HIV-infected patients who commenced efavirenz therapy were monitored for 36 months.

Results: In patients with baseline HDL-C<40 mg.

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